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Vaginitis clinical trials

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NCT ID: NCT00984399 Completed - Breast Cancer Clinical Trials

Serum Estradiol Levels In Postmenopausal Women With Breast Cancer Receiving Adjuvant Aromatase Inhibitors and Vaginal Estrogen

Start date: September 22, 2009
Phase: N/A
Study type: Interventional

The purpose of this study is to see if Vagifem® 10mcg is safe for women who have had breast cancer. Vagifem is an estrogen product. It is a tiny tablet that is inserted into the vagina. It relieves vaginal dryness. Women who have had breast cancer are usually told not to take estrogen. This is because estrogen use can lead to a breast cancer recurrence or a new primary breast cancer. It is unclear if the estrogen in Vagifem is only absorbed in the vagina. It may be absorbed into the blood stream for a short time and may cause a brief rise in your estrogen level. However, there is no clear evidence that this would cause any bad effects in patients with breast cancer. How much, if any, of these topical estrogens are absorbed through the vagina is not known. We also do not know what the impact is of low dose estrogen absorption on breast cancer outcomes. Also, the absorption should decrease as the mucus membranes are restored after estrogen exposure.

NCT ID: NCT00803127 Completed - Vaginitis Clinical Trials

VS-Sense Result Reading Clarity

Start date: January 2009
Phase: N/A
Study type: Observational

This study is designed to demonstrate the result reading clarity of the VS-SENSE is substantially equivalent to the result reading clarity of the Nitrazine pH Paper test for vaginal secretions.

NCT ID: NCT00634608 Completed - Obesity Clinical Trials

Integrating Targeted MedlinePlus Health Prescriptions Into Clinic Practice Workflow

Start date: February 2008
Phase: N/A
Study type: Interventional

The specific aim of this proposed project is to implement a standard process for integrating MedlinePlus health information prescriptions into the clinic workflow. Hypothesis 1: Individuals in the intervention group who receive tailored email health information with provider selected MedlinePlus links and added commentary for patient specific conditions will be more likely to seek information / use MedlinePlus compared with individuals in the control group. Hypothesis 2: Individuals in the intervention group who receive tailored email health information with provider selected MedlinePlus links and added commentary for patient specific conditions will be more satisfied with the information received compared with individuals in the control group.

NCT ID: NCT00616330 Completed - Vaginitis Clinical Trials

Vaginal Infection Study

Start date: January 2008
Phase: Phase 3
Study type: Interventional

This study will evaluate the efficacy and safety of a vaginal product compared with that of other vaginal products in the treatment of vaginal infections.

NCT ID: NCT00503542 Completed - Vaginitis Clinical Trials

Management of Vaginal Complaints: A Pilot Study Within a Practice-Based Research Network

VCAT
Start date: February 2007
Phase: Phase 0
Study type: Interventional

Many women present in primary care with vaginal complaints. The best way of managing these complaints is unclear. This trial will test two different methods of managing patients with vaginal complaints. This is a pilot trial.

NCT ID: NCT00465192 Completed - Menopause Clinical Trials

Efficacy and Safety of 17-Beta Estradiol in Treatment of Atrophic Vaginitis

Start date: August 31, 1994
Phase: Phase 3
Study type: Interventional

This trial was conducted in the United States of America (USA). This trial aimed for a comparison between the effect of two different doses of estradiol on parameters related to efficacy and safety.

NCT ID: NCT00464971 Completed - Menopause Clinical Trials

Evaluation of Safety and Efficacy of 17-Beta Estradiol in Treatment of Atrophic Vaginitis: An Extension Trial

Start date: January 31, 1995
Phase: Phase 3
Study type: Interventional

This trial was conducted in the United States of America (USA). This trial aimed to evaluate safety and efficacy of 17-beta Estradiol in the treatment of atrophic vaginitis.

NCT ID: NCT00313131 Completed - Bacterial Vaginosis Clinical Trials

Study of the Management of Vaginal Discharge in West African Using Single Dose Treatments

Start date: January 2004
Phase: Phase 3
Study type: Interventional

This randomised controlled trial aimed to verify whether directly observed single dose treatment (with tinidazole+fluconazole) would be as effective as the longer standard treatments (metronidazole for 7 days, plus vaginal clotrimazole for 3 days) in the syndromic management of women presenting with vaginal discharge in primary health care centers of Ghana, Togo, Guinea and Mali. It was designed as an effectiveness trial, i.e. it was done under conditions typical of routine work in these health centers

NCT ID: NCT00213057 Completed - HIV Infections Clinical Trials

Safety and Acceptability of Carraguard™ Among HIV-negative Couples in Thailand

Start date: June 2001
Phase: Phase 1
Study type: Interventional

The primary aims of the study were to assess the safety and acceptability of Carraguard applied vaginally prior to sexual intercourse for six months in both women and men; and to examine several dimensions of acceptability. Secondary aims were to gauge reactions to a non-contraceptive microbicide, to assess use dynamics among Thai couples and to observe preliminary indications of sexually transmitted infections and reproductive tract infections averted. The hypothesis was that Carraguard would cause little or no significant irritation, including lesions; and that women and men would find Carraguard acceptable.

NCT ID: NCT00213031 Completed - HIV Infections Clinical Trials

Safety, Acceptability and Preliminary Effectiveness of PC-515 for Vaginal Use as a Possible Microbicide

Start date: February 2000
Phase: Phase 2
Study type: Interventional

The primary aims of the study were to assess the safety and acceptability of PC-515 when applied vaginally at least three times weekly for 12 months. Secondary aims were to gather preliminary data on Carraguard's effectiveness in preventing male-to-female transmission of HIV, and other STIs. The hypothesis was that Carraguard would cause little or no significant irritation, including lesions; and that women would find Carraguard acceptable. The study was not powered to determine effectiveness, but based on safety, acceptability and feasibility parameters, the outcome of the Phase 2 trial would enable a decision whether or not to proceed to a Phase 3 trial.