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Uterine Hemorrhage clinical trials

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NCT ID: NCT01868308 Completed - Back Pain Clinical Trials

Screening To Obviate Preterm Birth

STOP
Start date: January 2013
Phase: N/A
Study type: Observational

Our objective is to investigate the predictive value of a panel of biomarkers associated with two biologically plausible pathways of preterm birth: membrane breakdown and cervical remodeling. The investigators will obtain cervical length, cervicovaginal fetal fibronectin, and a panel of novel cervicovaginal biomarkers associated with cervical remodeling in a prospective cohort of symptomatic women with a singleton pregnancy at high risk for preterm birth in an effort to better risk stratify this cohort.

NCT ID: NCT01817530 Completed - Uterine Fibroids Clinical Trials

Safety and Efficacy in Premenopausal Women With Heavy Menstrual Bleeding (HMB) Associated With Uterine Fibroids (UF)

Start date: April 8, 2013
Phase: Phase 2
Study type: Interventional

This is a Phase 2b randomized, double-blind, placebo-controlled study evaluating the safety and efficacy of elagolix alone and in combination with add-back therapy versus placebo on heavy menstrual bleeding in premenopausal women 18 to 51 years of age with uterine fibroids.

NCT ID: NCT01752725 Completed - Clinical trials for Focus: Comparison of Two Instruments

Comparison of BiCision® Versus UltraCision® During Laparoscopic Supracervical Hysterectomy (LASH)

Start date: October 2011
Phase: N/A
Study type: Interventional

The aim of the study is the evaluation of the efficiency and safety of the new, CE-certified thermofu-sion and dissection instrument BiCision® in comparison with the long established Ultracision® Har-monic Scalpel(Ethicon)during a laparoscopic supracervical hysterectomy (LASH).

NCT ID: NCT01726478 Completed - Uterine Hemorrhage Clinical Trials

Uterotonic Efficacy of Oxytocin 2.5 Versus 10 Units During Caesarean Section at Mulago Hospital

Start date: February 2011
Phase: N/A
Study type: Interventional

The purpose of the study was to determine whether 2.5 international units of oxytocin gives adequate uterine tone and is safe as compared to 10 international units of oxytocin following caesarean section delivery at Mulago hospital.

NCT ID: NCT01721304 Completed - Clinical trials for Abnormal Uterine Bleeding

Decisionmaking for Abnormal Uterine Bleeding (AUB)

Start date: May 2009
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if using a computer survey about preferences for treatment of abnormal uterine bleeding (AUB) is useful and if it will improve patient satisfaction with clinical care and decision making. This study is a two-part study. The first pilot tests the computerized tool to ensure it is understood by patients, then the second part is a randomized study (computerized tool versus usual care) to see if improvements are made in satisfaction and if there are reductions in decision regret.

NCT ID: NCT01709318 Completed - Contraception Clinical Trials

A Dose-Finding Study to Evaluate Ovarian Function and Vaginal Bleeding in Next Generation Rings (P06109/MK-8175A/MK-8342B-012)

Start date: December 12, 2012
Phase: Phase 2
Study type: Interventional

The primary objective of this trial was to identify at least one next generation ring (NGR) that demonstrates inhibition of ovulation (which was considered confirmed if in the subset of participants ovulation was observed in less than 15% of the participants at any time during the 3 treatment cycles of the study) and cycle control that was non-inferior to NuvaRing®, as judged by the incidence of breakthrough bleeding and/or spotting (BTB-S) during Cycle 3. The primary hypothesis was that at least 1 of the 6 NGRs would show inhibition of ovulation and cycle control during Treatment Cycle 3 that is non-inferior to NuvaRing®, as judged by the incidence of BTB-S.

NCT ID: NCT01628432 Completed - Cervical Dysplasia Clinical Trials

Effect of Salpingectomy During Conservative Hysterectomy

SALPINGOVA
Start date: July 2012
Phase: N/A
Study type: Interventional

The study compares the effect of bilateral salpingectomy associated with conservative hysterectomy on ovarian function to the standard hysterectomy with conservation of both ovaries and tubes in terms of hormone assays, ovarian ultrasound evaluation, complications, quality of life.

NCT ID: NCT01461824 Completed - Weight Gain Clinical Trials

Drug Exposure and Depot Medroxyprogesterone Acetate (DMPA) in Adolescent Subjects

Start date: September 2011
Phase: Phase 3
Study type: Interventional

The investigators are doing this study to look at how different doses of the Depot medroxyprogesterone acetate (DMPA) shot effect weight gain and bone mineral density in teens. The investigators hope that what the investigators learn from this study will be used to develop ways to keep girls from gaining weight or losing bone density when receiving DMPA.

NCT ID: NCT01441635 Completed - Uterine Fibroids Clinical Trials

Safety and Efficacy of Elagolix in Pre-Menopausal Women With Heavy Uterine Bleeding and Uterine Fibroids

Start date: September 8, 2011
Phase: Phase 2
Study type: Interventional

The purpose of this proof-of-concept study is to assess the safety and effectiveness of elagolix versus placebo to reduce uterine bleeding associated with uterine fibroids, and to reduce fibroid volume and uterine volume in premenopausal women 20 to 49 years of age with heavy uterine bleeding.

NCT ID: NCT01307007 Completed - Clinical trials for Iron Deficiency Anemia

Hypophosphatemia With Ferric Carboxymaltose Vs. Iron Dextran in Iron Deficiency Secondary to Heavy Uterine Bleeding

Start date: September 2010
Phase: Phase 2
Study type: Interventional

The primary objective of this study is to assess the safety of an investigational intravenous iron (ferric carboxymaltose [FCM]) or an equal dose of iron dextran and explore the mechanism of hypophosphatemia following administration of FCM or that of an equal dose of iron dextran when treating women with iron deficiency anemia due to heavy uterine bleeding (HUB).