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Uterine Hemorrhage clinical trials

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NCT ID: NCT06369012 Recruiting - Clinical trials for Abnormal Uterine Bleeding

Management of Abnormal Uterine Bleeding

Start date: March 1, 2024
Phase: N/A
Study type: Interventional

Abnormal uterine bleeding "AUB" describes all abnormal forms of menstrual bleeding which may result from several causes including anovulation, problems related to pregnancy, infections, vaginal and cervical abnormalities, uterine pathologies including benign and malignant tumors, coagulopathies, endocrine disorders, trauma, foreign bodies, systemic diseases and iatrogenic causes. AUB may be clinically presented by menorrhagia, metrorrhagia or menometrorrhagia. It's the most common complaint for the reproductive age females and accounts for 33% of female patients referred to gynecologists

NCT ID: NCT06308172 Recruiting - Clinical trials for Cesarean Section Complications

Impact of Single- Versus Double-layer Hysterotomy Closure on Cesarean Niche Development: a Randomized Controlled Trial

Start date: December 1, 2021
Phase: N/A
Study type: Interventional

The objective of this randomized monocentric study is to assess potential variations in the incidence and severity of isthmocele morbidity among women undergoing cesarean section with either single or double-layer closure of the hysterotomy. Our primary outcome aims to investigate whether there is a reduction in the median duration of intermenstrual spotting in patients belonging to the two respective closure groups

NCT ID: NCT06219538 Recruiting - Clinical trials for Cesarean Section Complications

DAISY Uterine Drain Device Evaluation

Start date: May 22, 2024
Phase: N/A
Study type: Interventional

The goal of this study is to obtain user feedback while placing and observing the DAISY uterine drain with wall suction. This study defines the obstetrical surgeons as "users" and the patients in whom the drain is placed as "participants." Participants are pregnant women who are undergoing cesarean delivery (CD), who have not entered active labor, who have consented to drain placement and who have met all the inclusion/exclusion criteria. Users are staff or fellow obstetrical surgeons who will use the drain and provide the evaluation.

NCT ID: NCT06193590 Recruiting - Clinical trials for Abnormal Uterine Bleeding

Suction Cervical Stabilizer Compared to Standard Tenaculum for Intrauterine Procedures

Start date: November 9, 2023
Phase: N/A
Study type: Interventional

To evaluate patient-reported pain, bleeding, and device efficiency along with provider satisfaction and ease of use between intrauterine procedures employing a suction cervical stabilizer (new device, FDA approved, atraumatic) or single-tooth tenaculum (standard, traumatic). This device, cleared by the FDA in 2023, was studied in Europe and showed pain reduced by up to 73% and bleeding reduced by 78% compared to the single-tooth tenaculum for intrauterine contraceptive device insertion. The investigators seek to study this device in the United States, and trial it among all intrauterine procedures.

NCT ID: NCT06106633 Recruiting - Uterine Fibroid Clinical Trials

Pain Reduction and Ovarian Perfusion Following Uterine Fibroid Embolization

PEDD-UFE
Start date: February 9, 2023
Phase: N/A
Study type: Interventional

The goal of this study is to assess of Pressure-Enabled Drug Delivery on fibroid treatment in patients undergoing UFE.

NCT ID: NCT06067217 Recruiting - Clinical trials for Abnormal Uterine Bleeding

Comparative Study of Tranexamic Acid, Estrogen for Treatment AUB in DMPA Users

Start date: September 30, 2023
Phase: N/A
Study type: Interventional

Abnormal uterine bleeding is the most common problems to discontinue Depo-medroxyprogesterone acetate (DMPA) in Thailand. This clinical trial use to provide drug to stop abnormal uterine bleeding from DMPA

NCT ID: NCT06024109 Recruiting - Ovarian Cancer Clinical Trials

Performance of SYMMCORA® vs. V-Loc® Suture Material in Patients Undergoing Laparoscopic Total Hysterectomy

BARHYSTER
Start date: March 19, 2024
Phase:
Study type: Observational

The aim of this study is to show the superiority of the new unidirectional barbed suture (SYMMCORA® mid-term, unidirectional) to conventional suture material in terms of time to perform the vaginal cuff closure during gynecologic surgeries without an increase in the complication rate. Secondly, the superiority of SYMMCORA®, mid-term unidirectional compared to the V-Loc®, unidirectional will be assessed regarding the mean time to close the vaginal cuff. The study will be performed in routine clinical setting, the only difference will be the randomization into two different suture groups. Both suture materials which will be applied to approximate the vaginal cuff are approved and carrying the CE-marks. Additionally, both sutures will be applied in their intended use. Neither additional invasive measures nor additional burden in regard to the patient will be performed.

NCT ID: NCT05922657 Recruiting - Menorrhagia Clinical Trials

A Registry to Gather Real World Use Data on the Cerene® Cryotherapy Device

Progress
Start date: June 9, 2023
Phase:
Study type: Observational [Patient Registry]

Channel Medsystems, Inc., the manufacturer of the Cerene® Cryotherapy Device (Cerene), is initiating a prospective, observational registry, the Progress registry, to gather data during real world utilization of the Cerene® Cryotherapy Device (Cerene). The primary objective of this registry is to bridge the gap between clinical results and outcomes achieved and reported during the pivotal study of Cerene and those obtained during its real-world use.

NCT ID: NCT05304442 Recruiting - Clinical trials for Anemia, Iron Deficiency

IV Iron Trial for Anemia Related to Uterine Bleeding in Female Patients Presenting to the Emergency Department

Start date: September 15, 2022
Phase: Phase 3
Study type: Interventional

The primary aim of this randomized trial is to assess the efficacy of IV Ferric Derisomaltose vs Oral Iron in the management of women with severe Iron Deficiency Anemia due to Uterine Bleeding in the emergency department.

NCT ID: NCT05153928 Recruiting - Clinical trials for Abnormal Uterine Bleeding

Management of Uterine Leiomyomata and Adenomyosis

Start date: April 10, 2021
Phase:
Study type: Observational

1. to determine the role of hysteroscopy and guided biopsy to differentiate between submucosal fibroids and adenomyosis confirmed by histopathological examination 2. to evaluate the efficacy of norethisterone in the treatment of symptomatic adenomyosis and leiomyoma