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Abnormal Uterine Bleeding clinical trials

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NCT ID: NCT04475497 Recruiting - Clinical trials for Abnormal Uterine Bleeding

Role of Blood Management in Perioperative Outcomes

Start date: July 24, 2020
Phase: N/A
Study type: Interventional

There is currently limited information regarding the role of blood management in the benign gynecologic population and specifically, in patients who are scheduled to undergo surgery for fibroids and/or abnormal uterine bleeding. A thorough search through PubMed and clinicaltrials.gov did not reveal any studies on this issue. In 2019 at CCF only 2% of gyn patients at Main Campus were referred to blood management, but 12.6% of the main campus gyn population had a Hb of <10.0 g/dL. The overall goal of this study is to evaluate the role of preoperative blood management in optimizing surgical outcomes by reducing the co-morbidities associated with postoperative blood transfusion.

NCT ID: NCT04434066 Recruiting - Surgery Clinical Trials

Outcomes on Abdominal Versus Vaginal Morcellation At Time of Hysterectomy

Start date: January 8, 2020
Phase: N/A
Study type: Interventional

The purpose of the study is to investigate differences in perioperative and postoperative outcomes between the abdominal (AM) versus vaginal (VM) routes of contained morcellation in participants undergoing laparoscopic total hysterectomies in a randomized controlled trial.

NCT ID: NCT04381416 Recruiting - Clinical trials for Abnormal Uterine Bleeding

Study to Assess the Safety and Efficacy of the IUB SEADâ„¢ Device

AUB
Start date: September 1, 2019
Phase: N/A
Study type: Interventional

Pre-pivotal, randomized study to assess the safety and efficacy of the IUB SEADâ„¢ device in women suffering from abnormal uterine bleeding.

NCT ID: NCT04311073 Recruiting - Clinical trials for Abnormal Uterine Bleeding

Prophylactic Tranexamic Acid During Minimally Invasive Myomectomies

Start date: June 20, 2020
Phase: Phase 3
Study type: Interventional

This is a Double-blinded randomized placebo-controlled trial based at Eastern Virginia Medical School. Subjects who are identified in clinic having menorrhagia or abnormal Uterine bleeding (AUB) due to uterine fibroids and meet inclusion criteria based on the ultrasound (US) or Magnetic Resonance Imaging (MRI), aged 18-45 undergoing laparoscopic or Robotic assisted myomectomies. A total of 50 women in each arm of the study with symptomatic fibroids. Patients will be randomized to receive a single IV bolus injection of TXA 30mg/kg in 50ml of normal saline (intervention group) versus an IV bolus injection of normal saline of equivalent volume (placebo group) 15 minutes prior to initial surgical incision.

NCT ID: NCT04172272 Recruiting - Chronic Pain Clinical Trials

The Influence of TAP Block in the Control of Postoperative Pain After Laparotomy for Gynecological Procedures

TAP
Start date: September 24, 2019
Phase: N/A
Study type: Interventional

This study evaluates the influence of the transversus abdominis plane block on the intensity of postoperative pain and the concentration of proinflammatory and pain factors after hysterectomy by laparotomy. The patients will be randomized in three groups.In the first group, patients will receive intravenous, systemic, multimodal analgesia.In the second group there will be patients in who will be given the TAP block. The TAP block will be given postoperatively before waking. It will be given bilaterally in the before mentioned anatomic region (the so-called lateral TAP block). In the third group there will be patients who will be treated with TAP block in addition to systemic, mutimodal analgesia. The research will be based on completing a questionnaire (VAS scale and QoR questionnaire) and taking peripheral blood out. We expect that the concentration of proinflammatory and pain factors in patients treated with a TAP block will be lower and the quality of recovery will be better than that of patients receiving standard analgesic therapy (systemic multimodal analgesia).

NCT ID: NCT03930303 Completed - Anxiety Clinical Trials

Anxiety Scores With Media Based Patient Education Before Dilatation and Curettage

Start date: August 23, 2019
Phase: N/A
Study type: Interventional

Subjects with abnormal uterine bleeding and scheduled for dilatation and curettage (D&C) will be randomized to a multimedia-based education (MME group) or verbal information (Control group ) before (D&C). State-Trait Anxiety Inventory will be asked by the nursing staff before and after multimedia-based education or verbal information to all patients. Then the patients will undergo (D&C) at an office setting. The impact of MME on patient anxiety will be evaluated by statistical analysis.

NCT ID: NCT03809468 Completed - Clinical trials for Abnormal Uterine Bleeding

Patient Satisfaction With Initial Phone Call Versus Office Visit Following Minimally Invasive Hysterectomy, a Randomized Controlled Trial.

Start date: January 16, 2019
Phase: N/A
Study type: Interventional

Patients will be randomized to clinic or telephone follow up after outpatient TLH. surveys will document patient satisfaction.

NCT ID: NCT03697733 Completed - Clinical trials for Abnormal Uterine Bleeding

Comparison Efficiency of Oral Etoricoxib Versus Intravenous Fentanyl on Post Operative Pain in Curettage Under TIVA

Start date: November 1, 2018
Phase: N/A
Study type: Interventional

Comparison of the efficiency of oral Etoricoxib versus intravenous Fentanyl on post operative Pain in curettage under TIVA: A randomized controlled trial

NCT ID: NCT03638856 Completed - Infertility, Female Clinical Trials

Comparing Effectiveness of Oral Misoprostal for Cervical Priming in Hysteroscopy

Start date: September 30, 2018
Phase: N/A
Study type: Interventional

Research objective To compare effectiveness of oral Misoprostal for cervical priming in premenopausal women underwent to diagnostic hysteroscopy Research hypothesis: Null hypothesis Effectiveness of oral misoprostal for cervical priming in premenopausal women underwent to diagnostic hysteroscopy is not different from placebo Alternative hypothesis: : Oral Misoprostal for cervical priming in Premenopausal women underwent to diagnostic hysteroscopy is better than placebo

NCT ID: NCT03441087 Completed - Clinical trials for Abnormal Uterine Bleeding

The Role of TVSG and HS in Determining Endometrial Pathologies

Start date: January 1, 2011
Phase: N/A
Study type: Interventional

Although hysteroscopy (HS) and transvaginal ultrasonography (TVSG) are methods in the diagnosis of AUB, there is some suspicion about their efficacy. The aim of this study was to determine the efficacy and safety of HS and TVSG on diagnosing abnormal uterine bleeding(AUB) .216 women admitted to the investigators clinic (Sisli Ethal Training and Research Hospital, Obstetrics and Gynecology Department Obstetrics Service ) between 21-51 years of age. These patients were divided into two groups; menopause (71women) and pre-menopause (145 women). HS and endometrial sampling were performed both groups after TVSG.The success of these methods was assessed by kappa analysis