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Uterine Hemorrhage clinical trials

View clinical trials related to Uterine Hemorrhage.

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NCT ID: NCT05645848 Not yet recruiting - Placenta Previa Clinical Trials

The Rate and Predictors of Vaginal Bleeding Among Women With Placenta Previa

Start date: December 2022
Phase:
Study type: Observational

Placenta previa is usually diagnosed when the placenta implanted in the lower uterine segment, thus partially or totally overlying the internal os . It occurs with an incidence of 0.3-0.5%. It is associated mainly with prior caesarean delivery . The condition is frequently complicated by invasion of placental villi beyond the decidua basalis causing placenta accreta . Placenta previa is a major cause of massive haemorrhage during pregnancy and after delivery . The antepartum bleeding from placenta previa- can be life-threatening, thus, the prediction of this bleeding is of great importance . It is important to distinguish between women at high and low risk for antepartum haemorrhage with placenta previa especially at late pregnancy . However, the potential risk factors for antepartum haemorrhage in women with placenta previa have not been thoroughly examined.

NCT ID: NCT05594186 Completed - Clinical trials for Intermenstrual Bleeding

Nonsurgical Management of Cesarean Scar Niche Related Abnormal Uterine Bleeding

Start date: March 1, 2019
Phase: N/A
Study type: Interventional

A study of the effect of three different nonsurgical methods for management of abnormal uterine bleeding caused by cesarean scar niche. The study was conducted at the Obstetrics and Gynaecology department of the Saudi German Hospital in Madinah- Saudi Arabia, during the period between March 2019 to October 2022. The study protocol was in accordance with the Helsinki declaration 1964 and the later amendments. A prospective approval was granted by the human research ethics committee of the hospital and the study participants have signed an informed consent.

NCT ID: NCT05483348 Completed - Uterine Bleeding Clinical Trials

Clinical Predictive Factors of Success of Hysteroscopic Endometrial Ablation/Resection

Start date: February 17, 2022
Phase:
Study type: Observational

To determine the predictive factors of endometrial ablation failure in the management of uterine bleeding.

NCT ID: NCT05474703 Active, not recruiting - Clinical trials for Abnormal Uterine Bleeding

Evaluation of the Effects of Levonorgestrel-releasing Intrauterine Device and Dydrogestreone on Quality of Life and Sexual Life in Patients With Abnormal Uterine Bleeding.

Start date: February 20, 2022
Phase:
Study type: Observational [Patient Registry]

This study was retrospectively collected from patients who were diagnosed with abnormal uterine bleeding and received oral dydrogesterone therapy for at least six months or who were administered an intrauterine device containing levonorgestrel at least six months ago, and prospectively Short form 36 (P-36); It covers the comparison of the Quality of Life Scale and the Female Sexual Function Scale (FSFI) by asking over the phone.

NCT ID: NCT05423067 Completed - Clinical trials for Other Abnormal Uterine and Vaginal Bleeding

Permanent Occlusion of Uteine Arteies in Management of Abnormal Uterine Bleeding

Start date: October 2011
Phase: Phase 1/Phase 2
Study type: Interventional

Prospective observational interventional study , The study done in two phases: 1. Phase one from October 2011to May 2012 pilot study including twenty nine (29) premenopausal patients followed up for six months 2. Phase two from October 2012 till May 2014. Including Eighty nine (89) premenopausal patients all of them needing to preserve their uteri.

NCT ID: NCT05406960 Completed - Hysterectomy Clinical Trials

Therapeutic Effect of Herbal Infusion on Menometrorrhagia

HERBALTREAT
Start date: May 10, 2019
Phase: N/A
Study type: Interventional

This is an interventional, non-randomized, controlled, pilot study that explores a new approach to treat, Abnormal uterine bleeding-menometrorrhagia in women, being candidates for hysterectomy, based on tea infusion consumption of a mixture of two plants.

NCT ID: NCT05378152 Completed - Endometrial Cancer Clinical Trials

Assessing the Benefit of Pipelle Biopsy in Patients With Postmenopausal Bleeding and an Atrophic-appearing Cavity

Start date: September 24, 2022
Phase: N/A
Study type: Interventional

Postmenopausal bleeding (PMB) is the occurrence of vaginal bleeding 12 months following a woman's last menstrual cycle. PMB represents one of the most common reasons for referral to gynaecology services. Approximately 10% of women with PMB will be found to have endometrial cancer. The gold standard of investigation of PMB is ambulatory gynaecology through the outpatient hysteroscopy clinic, which is often combined with Pipelle biopsy for endometrial sampling. Up to 60% of women that present with PMB will have an atrophic-appearing cavity at hysteroscopy. This provides a challenge in obtaining a histological sample through both dilatation & curretage (D&C) and Pipelle biopsy. Often, scant tissue that is insufficient for clinical diagnosis is obtained. Pipelle biopsy is associated with patient discomfort. It is also associated with costs related to the purchasing of equipment and the processing of samples in the laboratory to the sum of approximately 30 euro per sample. It is rare that a sample taken from an atrophic cavity will return any clinically meaningful result. A negative hysteroscopy reduces the probability of endometrial cancer to 0.6%. This study aims to compare patients with PMB and atrophic-appearing cavity that undergo pipelle biopsy to those that do not. Differences in pain scores, cost saving and differences in clinical follow up will be assessed to evaluate the benefit of Pipelle biopsy in patients with PMB and atrophic-appearing cavity.

NCT ID: NCT05304442 Recruiting - Clinical trials for Anemia, Iron Deficiency

IV Iron Trial for Anemia Related to Uterine Bleeding in Female Patients Presenting to the Emergency Department

Start date: September 15, 2022
Phase: Phase 3
Study type: Interventional

The primary aim of this randomized trial is to assess the efficacy of IV Ferric Derisomaltose vs Oral Iron in the management of women with severe Iron Deficiency Anemia due to Uterine Bleeding in the emergency department.

NCT ID: NCT05299801 Active, not recruiting - Clinical trials for Abnormal Uterine Bleeding

DAta MIning to Evaluate Novasure Treatment

DAMIEN
Start date: July 1, 2021
Phase:
Study type: Observational

Abnormal Uterine Bleeding (AUB) is a common health problem that affects approximately 30% of women of reproductive age and can have several underlying causes. It significantly affects quality of life, use of medical resources and health costs. Endometrial ablation is a commonly used minimally invasive surgical procedure for the treatment of AUB that destroys endometrial tissue. This procedure is an alternative treatment to hysterectomy because it is less invasive and has a shorter recovery period. Several ablation techniques are available to remove endometrial tissue, including bipolar radiofrequency (NovaSure treatment). While patient satisfaction with this form of endometrial ablation for the treatment of AUB is high, approximately 10-20% of women undergoing endometrial ablation require additional invasive surgery, primarily because of persistent blood loss or pain. There is therefore a need to identify and evaluate factors that can improve women's outcomes, or that can be building blocks for prognostic models that can be used to influence clinical practice. In this 10-year single-center retrospective cohort study, we aim to apply data mining and machine learning techniques to uncover hidden relationships/patterns between variables, and identify factors and patients at increased risk for Novasure treatment failure. With multiple time variables, this is not possible with a simple statistical analysis. Discovering these patterns and risk factors could help improve medical care, patient counseling and patient satisfaction.

NCT ID: NCT05270473 Completed - Clinical trials for Bleeding in Cesarean Section

Efficacy of Compression Sutures in Controlling Excessive Uterine Bleeding During Caesarean Section

Start date: March 20, 2022
Phase: N/A
Study type: Interventional

The investigators found that B- Lynch suture is more effective than Nausicca suture in controlling excessive uterine bleeding during cesarean section and avoiding the need of hysterectomy. Also, the investigators found that B- lynch suture needs shorter procedure time with less blood loss compared to Nausicca suture. Consequently the investigators recommend the use of B-Lynch suture as a compressive uterine suture to control excessive uterine bleeding during cesarean section and avoid the need of hysterectomy. As a result of this study the investigators recommend further studies to compare different uterine compressive suture to verify the most effective uterine compressive suture.