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Placenta Previa clinical trials

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NCT ID: NCT06220760 Not yet recruiting - Placenta Accreta Clinical Trials

Outcomes of Placenta Accreta Spectrum Disorders Surgery in Relation to Placenta Accreta Scoring Index

Start date: February 20, 2024
Phase:
Study type: Observational

Using of Ultra sound in assessment of Placenta Accreta Index to predict the surgical outcomes of Placenta accreta

NCT ID: NCT06219564 Completed - Maternal; Procedure Clinical Trials

Total Placenta Previa Associated With the Placenta Accreta Spectrum.

PAS
Start date: November 1, 2017
Phase: N/A
Study type: Interventional

To assess the reliability of placental magnetic resonance imaging measurements in predicting peripartum hysterectomy and neonatal outcomes in patients with total placenta previa.

NCT ID: NCT06030492 Recruiting - Placenta Accreta Clinical Trials

Efficacy of Hydrogen Peroxide ( H2O2) in Controlling Placental Site Bleeding in Caesarian Delivery for Placenta Previa / Accreta Spectrum ( PAS)

Start date: January 1, 2023
Phase: N/A
Study type: Interventional

Placenta accreta spectrum (PAS), encompassing the terms placenta accreta, increta, and percreta; abnormally invasive placenta; morbidly adherent placenta; and invasive placentation, is a leading cause of life-threatening obstetric haemorrage (1) . Currently, more than 90% of women diagnosed with PAS also have a placenta praevia (2), and the combination of both conditions leads to high maternal morbidity and mortality due to massive haemorrhage at the time of birth . Maternal mortality of placenta praevia with percreta has been reported to be as high as 7% of cases . Hydrogen peroxide is well-known for its antimicrobial and antiseptic properties. It is used to clean surgical cuts for better localization of bleeding focus in surgery and orthopedics and burn excisions to induce hemostasis . Topical application of hydrogen peroxide was proven to induce hemostasis and reduce operative time in both tonsillectomy and adenoidectomy .

NCT ID: NCT06030479 Recruiting - Placenta Accreta Clinical Trials

Topical Adrenaline Versus Warm Saline Solution for Minimizing Intraperitoneal Bleeding During Caesarian Delivery for Placenta Previa / Accreta Spectrum ( PAS)

Start date: February 1, 2023
Phase: N/A
Study type: Interventional

Placenta accreta spectrum (PAS), encompassing the terms placenta accreta, increta, and percreta; abnormally invasive placenta; morbidly adherent placenta; and invasive placentation, is a leading cause of life-threatening obstetric haemorrage . Currently, more than 90% of women diagnosed with PAS also have a placenta praevia , and the combination of both conditions leads to high maternal morbidity and mortality due to massive haemorrhage at the time of birth . Maternal mortality of placenta praevia with percreta has been reported to be as high as 7% of cases . Adrenaline has also been demonstrated to be a reasonable hemostatic agent because of its low cost, low risk, powerful vasoconstrictor, and platelet aggregation. Topical use of adrenaline is an effective and reasonable hemostatic agent in tonsillectomy.

NCT ID: NCT06029985 Completed - Placenta Accreta Clinical Trials

Hysteroscopic Follow-up Following Conservative Stepwise Surgical Approach for Management of Placenta Previa Accreta

Start date: June 1, 2020
Phase:
Study type: Observational

Conservative management of placenta accreta spectrum can preserve future fertility but should only be done in hospitals with enough experience as it carries a high risk of maternal complications. Follow up after conservative management is crucial to detect complications early.

NCT ID: NCT05811676 Recruiting - Placenta Previa Clinical Trials

Tranexamic Acid for the Prevention of Postpartum Hemorrhage in Pregnant Women With Placenta Previa

TRAPP
Start date: July 12, 2023
Phase: Phase 3
Study type: Interventional

Many RCT(randomized controlled trial) studies reported that tranexamic acid reduced blood loss in women who had elective cesareans. However, most of these elective cesareans are without high-risk factors of postpartum hemorrhage, such as placenta previa. The prophylactic use of tranexamic acid in the placenta previa is not clear. studies had poor quality and lacked adequate power to assess severe adverse events.

NCT ID: NCT05802251 Recruiting - Placenta Previa Clinical Trials

Sonographic Parameters and Risk of Antepartum Hemorrhage in Asymptomatic Women With Placenta Previa: A Cohort Study

Start date: June 1, 2022
Phase:
Study type: Observational

The aim of this study is to evaluate the effectiveness of ultrasonographic parameters (cervical length, placental thickness and distance placental edge from internal os of the cervix) in predicting the risk of antepartum hemorrhage and emergency cesarean delivery in asymptomatic women with placenta previa.

NCT ID: NCT05688111 Completed - Clinical trials for Interventional Drug in Placenta Previa

Tranexamic Acid as an Intervention in Placenta Previa

Start date: January 10, 2022
Phase: N/A
Study type: Interventional

Antepartum hemorrhage (APH) due to placenta previa is an important cause of worldwide perinatal mortality and maternal morbidity in pregnant women

NCT ID: NCT05645848 Not yet recruiting - Placenta Previa Clinical Trials

The Rate and Predictors of Vaginal Bleeding Among Women With Placenta Previa

Start date: December 2022
Phase:
Study type: Observational

Placenta previa is usually diagnosed when the placenta implanted in the lower uterine segment, thus partially or totally overlying the internal os . It occurs with an incidence of 0.3-0.5%. It is associated mainly with prior caesarean delivery . The condition is frequently complicated by invasion of placental villi beyond the decidua basalis causing placenta accreta . Placenta previa is a major cause of massive haemorrhage during pregnancy and after delivery . The antepartum bleeding from placenta previa- can be life-threatening, thus, the prediction of this bleeding is of great importance . It is important to distinguish between women at high and low risk for antepartum haemorrhage with placenta previa especially at late pregnancy . However, the potential risk factors for antepartum haemorrhage in women with placenta previa have not been thoroughly examined.

NCT ID: NCT05560984 Not yet recruiting - Clinical trials for Cervical IO Plasty in Management of Placenta Previa

Cervical Internal os Plasty in Management of Placenta Previa and Focal Accreta

Start date: October 2022
Phase: N/A
Study type: Interventional

Aim of the work: Better management & reducing hemorrhage and complication in patients placenta previa and focal accreta .