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Urinary Incontinence, Stress clinical trials

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NCT ID: NCT03474653 Active, not recruiting - Clinical trials for Urinary Incontinence

LATITUDE An Observational Study of Patient Choice and the Urethral Bulking Agent, Bulkamid®

Start date: June 12, 2017
Phase:
Study type: Observational

Latitude is an observational study exploring how effective Bulkamid ® is as a first line treatment for women with stress urinary incontinence. Women who choose to have Bulkamid as part of their standard clinical care will be asked to complete questionnaires before and after their surgery so that we can assess how their urinary symptoms change. As a second part of the study, we are asking all patients having any first line treatment for stress incontinence to complete a short questionnaire telling us how they decided what treatment to have. A small number of these women will be contacted via telephone and asked whether they would mind being interviewed to tell us more about this. We will also interview a number of doctors taking part in Latitude to find out how they counsel patients about different treatment options for stress urinary incontinence.

NCT ID: NCT03473041 Not yet recruiting - Clinical trials for Stress Urinary Incontinence

Autologous Rectus Sheath Fascia Versus Midurethral Transobturator Tension Free Vaginal

Start date: March 2018
Phase: Phase 3
Study type: Interventional

a hybrid sling formed of a central part of autologus rectus sheath (2×6 cm) and two arms of polypropylene mesh (2×10cm) versus transobturator tension free vaginal tape(TVT-O)

NCT ID: NCT03463863 Completed - Clinical trials for Stress Urinary Incontinence

Midurethral Sling With Autologus Rectus Sheath

Start date: August 10, 2016
Phase: Phase 3
Study type: Interventional

assessment of the safety and efficacy surgeon tailored rectus sheath midurethral sling

NCT ID: NCT03443687 Completed - Quality of Life Clinical Trials

Systematized Quality Exercise Alternatives for Stress Incontinence

SQEASI
Start date: June 1, 2018
Phase: N/A
Study type: Interventional

This randomized controlled study evaluates the effect of home biofeedback compared to pelvic floor physical therapy for the treatment of stress urinary incontinence. Half of the participants will use a home biofeedback device for 3 months and the other half will attend pelvic floor physical therapy appointments for 3 months.

NCT ID: NCT03439527 Completed - Clinical trials for Urinary Stress Incontinence

Multisystem Cell Therapy for Improvement of Urinary Continence

MUSIC
Start date: January 22, 2020
Phase: Phase 1
Study type: Interventional

The rising success of cell therapies places an increasing burden on health care costs. Consequently, the need to reduce production costs while maintaining quality has been widely acknowledged. In addition, the demand for high-quality products with an optimal safety profile is increasing. The proposed cell treatment is the first therapeutical option with the possibility to revert the underlying condition. The investigators expect that this healing response will be achieved with minimal side effects justifying the addional costs and complexity.

NCT ID: NCT03401983 Completed - Clinical trials for Stress Urinary Incontinence

Effectiveness of Pelvic Floor Muscle and Abdominal Training in Women With Stress Urinary Incontinence

Start date: September 1, 2016
Phase: N/A
Study type: Interventional

The aim of this study was to investigate the effectiveness of pelvic floor muscle and abdominal training in reproductive-age patients with stress urinary incontinence. This prospective randomized controlled design study included 64 female patients aged 18-49 years with stress urinary incontinence. The patients were divided into 2 groups (32 PFMT "Pelvic Floor Muscle Training" and 32 PFMT+AT "Abdominal Training") by computer-based randomization. The stress urinary incontinence type was assessed by a stress test, and the pelvic floor muscle strength was measured with a home biofeedback device. Voiding functions were assessed by a 3-day voiding diary and uroflowmetric test. The UDI-6 scale was used to assess the urinary symptoms, and the IIQ-7 scale was used to assess the quality of life. The follow-up measurements of both groups were obtained in the 0th, 4th, and 8th weeks.

NCT ID: NCT03397368 Recruiting - Clinical trials for Stress Incontinence, Female

Evaluation of Transperineal US in Stress Incontinence

Start date: January 16, 2018
Phase:
Study type: Observational [Patient Registry]

Stress urinary incontinence (SUI) has an observed prevalence of between 4%and 35%.Identified risk factors are aging, obesity and repeated pregnancies and deliveries. Urodynamic remains the gold standard for diagnosis in the past years. Trans labial ultrasound appears to have a good role in diagnosing stress incontinence

NCT ID: NCT03353714 Completed - Clinical trials for Stress Urinary Incontinence

The Effect of Pudendal Blocks on Voiding Dysfunction Following Slings

PUBS
Start date: October 1, 2017
Phase: N/A
Study type: Interventional

To determine the effect of a bilateral pudendal block on voiding dysfunction following midurethral slings.

NCT ID: NCT03332654 Completed - Multiple Sclerosis Clinical Trials

Stress Urinary Incontinence in Women With Multiple Sclerosis

UROSEP
Start date: February 1, 2015
Phase: N/A
Study type: Observational

Objective: To report the prevalence and risk factors of stress urinary incontinence (SUI) and the prevalence of intrinsic sphincter deficiency in women with multiple sclerosis (MS). Methods: A retrospective study was conducted among Female patients with MS, followed for lower urinary tract symptoms (LUTS) during a 15-year period. Demographic data, MS history, expanded disability status scale (EDSS) score at the urodynamic visit, obstetrical past, birth weight, LUTS, and urodynamic findings were collected. SUI was defined as incontinence during cough, or any effort. A maximum urethral closure pressure less than 30 cm H2O defined intrinsic sphincter deficiency. Results: In total 363 women with a mean age of 46.7±10.8 years and a mean disease duration of 12.9±8.7 years were included. The incidence of relapsing remitting MS, a secondary progressive form, and a primary progressive form was 60.6%, 32.8%, and 6.6%, respectively. The prevalence of SUI was 31.4%. The prevalence of intrinsic sphincter deficiency was 1.4% and 0.8% of these patients had a SUI (P=0.300). In a multivariate analysis, women with a SUI had significantly higher birth weight (P=0.030), a pelvic organ prolapse (P=0.021), urgent urinary incontinence (P=0.006), a lower EDSS score (P=0.019), and a weaker containing effort (P<0.001). Conclusions: The prevalence of SUI in women with MS was 31.4%. This symptom could affect the quality of life of women with MS.

NCT ID: NCT03325543 Not yet recruiting - Clinical trials for Urinary Incontinence

Can Women Correctly Contract Their Pelvic Floor Muscles After to Receive Verbal Instructions and Vaginal Palpation?

Start date: December 1, 2017
Phase: N/A
Study type: Interventional

The pelvic floor muscle training (PFMT) is a conservative treatment, currently considered as first line for women with stress urinary incontinence (SUI). However, in practice, about 30 to 50% of women are unable to perform the correct contraction of the pelvic floor muscles (PFMs). When requested to perform the muscle contraction, the contraction of the gluteal muscles, hip adductors, or abdominal muscles is observed initially, rather of contraction of the levator anus muscle. Some factors make it difficult to perform the contraction of the PFM, such as its location on the pelvic floor, and its small size, followed by a lack of knowledge of the pelvic region, as well as its functions. Associated with these factors is the use of the muscles adjacent to the PFM, as previously mentioned. In order for women to benefit from a PFMT program for the treatment of SUI, the awareness phase of PFM can't be omitted, since the literature is unanimous in stating that pelvic exercises improve the recruitment capacity of the musculature, its tone and reflex coordination during the effort activities.