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Urinary Calculi clinical trials

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NCT ID: NCT06331546 Recruiting - Healthy Clinical Trials

Gut Oxalate Absorption in Calcium Oxalate Stone Disease

Start date: April 1, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial study is to test if patients with idiopathic calcium oxalate kidney stones have an increased absorption of dietary oxalate, which would lead to increased urinary excretion of oxalate. The study will recruit adult patients with a history of calcium oxalate kidney stones and healthy volunteers without kidney stones. Participants will - ingest fixed diets containing low and moderately high amounts of oxalate for 5 days at a time - ingest a soluble form of oxalate and sugar preparations to test gut permeability - collect urine, blood, stool and breath sample during the fixed diets and the soluble oxalate test

NCT ID: NCT06330246 Recruiting - Urolithiasis Clinical Trials

O. Formigenes Colonization in Calcium Oxalate Kidney Stone Disease

Start date: April 1, 2024
Phase: N/A
Study type: Interventional

The goal of this trial is to test if colonization with the gut bacteria Oxalobacter formigenes leads to a reduction in urinary oxalate excretion in patients with calcium oxalate kidney stone disease. The study will recruit adult participants with a history of calcium oxalate kidney stones who are not colonized with Oxalobacter formigenes. Participants will - ingest fixed diets containing low and moderately high amounts of oxalate for 4 days at a time - collect urine, blood and stool samples during the fixed diets - ingest a preparation of live Oxalobacter formigenes to induce colonization with Oxalobacter formigenes

NCT ID: NCT06306222 Recruiting - Kidney Stone Clinical Trials

Thulium Fiber Laser vs. Holmium:YAG Laser for the Ureteroscopic Treatment of Patients With Urinary Stone Disease

Start date: November 23, 2023
Phase: N/A
Study type: Interventional

This is a randomized controlled trial which aims to compare the efficacy and safety of Thulium fiber laser (TFL) and holmium:yttrium-aluminum-garnet (Ho:YAG) laser ablation during the treatment of upper urinary tract stone disease with flexible ureteroscopy, demonstrating clinical superiority of TFL.

NCT ID: NCT06269783 Recruiting - Urolithiasis Clinical Trials

Dual-process Mechanisms of Action for sipIT Intervention Effects in Patients With Urolithiasis

Start date: January 10, 2024
Phase: N/A
Study type: Interventional

The purpose of this study is to clarify the fundamental processes underlying behavior change, maintenance, and adherence during and after a 3-month fluid intake intervention period.

NCT ID: NCT06176469 Recruiting - Urolithiasis Clinical Trials

Renal Colic and Urolithiasis in Poland

POLSTONE
Start date: December 1, 2023
Phase:
Study type: Observational

The aim of this study is to analyze the prevalence, effect on quality of life, and treatment-related behaviors for renal colic and urolithiasis in a population-representative sample of Poles. We will be using an Internet interview format for renal colic and urolithiasis evaluation. The study will include respondents representative for age and place of residence with adequate proportions of respondents from urban and rural areas.

NCT ID: NCT06032364 Recruiting - Urinary Lithiasis Clinical Trials

Stone Disease of the Urinary Tract in Children

Ped-Urolithia
Start date: August 23, 2023
Phase:
Study type: Observational

The incidence of stone disease of the urinary tract in children is increasingly increasing with a remarkable economic impact for its management. This incidence is variable according to race, geographic region, socio-economic status and dietary habits. Oxalo-calcium stones are the most common but the biochemical nature of urinary stones varies depending on the region where those of a phosphatic nature are characterized by a higher incidence in Europe. The diagnosis is confirmed by imaging. The unprepared abdomen (ASP) has low diagnostic accuracy. The scanner is the reference tool but remains an irradiating examination. Risk factors for disease recurrence include primarily the presence of an underlying urinary metabolic abnormality and young age. Urinary metabolic abnormalities vary from one study to another. The understanding of lithogenesis, its evaluation as well as the therapeutic options is essential for adequate and adapted management in the pediatric population.

NCT ID: NCT06022952 Recruiting - Urolithiasis Clinical Trials

The Impact of the "Stone MD" Mobile App on the Prevention of Forgotten Ureteral Stents

Start date: February 1, 2023
Phase: N/A
Study type: Interventional

The Impact of the "Stone MD" Mobile App on the Prevention of Forgotten Ureteral Stents

NCT ID: NCT06003348 Recruiting - Clinical trials for Calcium Phosphate Kidney Stones

Hydroxycitrate: A Novel Therapy for Calcium Phosphate Urinary Stones

Start date: October 11, 2023
Phase: Phase 4
Study type: Interventional

This study tests whether hydroxycitrate, a molecule closely related to citrate, can reduce calcium phosphate stone recurrence.

NCT ID: NCT05872230 Recruiting - Nephrolithiasis Clinical Trials

Massage Percussion for Passage of Urolithiasis Fragments After Ureteroscopy.

Start date: February 1, 2024
Phase: N/A
Study type: Interventional

Flexible ureteroscopy is characterized as first-line therapy for renal stones < 2 cm in size. Stones are commonly treated with dusting or fragmentation techniques which requires passage of stone fragments after surgery. Quoted stone free rate after flexible ureteroscopy is approximately 40-60% with a dusting technique. Residual fragments are often under 1mm in size and can layer in the lower pole of the kidney, complicating spontaneous stone passage. Improving the stone free rate after surgery decreases the need for secondary surgeries and decreases risk of future stone events. Numerous techniques have been proposed to increase stone passage including positional changes and percussion therapy. To date, there is overall limited data a lack of techniques that can be readily available in the outpatient setting, easily added to scheduled appointments, reproducible results and well tolerated by patients.

NCT ID: NCT05712785 Recruiting - Urinary Calculi Clinical Trials

Shuotongo Ureteroscopy for Upper Urinary Tract Stones

SFUUTS
Start date: January 1, 2020
Phase: N/A
Study type: Interventional

The purpose of this study is to use the Shuotong ureteroscopy for surgical treatment of patients with upper urinary tract stones, taking advantage of the fact that the Shuotong mirror can be used for simultaneous lithotripsy and stone removal, thus maximizing the discharge of stones from the body and improving the stone removal rate.