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Urinary Calculi clinical trials

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NCT ID: NCT06007352 Not yet recruiting - Sepsis Clinical Trials

Use of Antibiotic Based Irrigation for Ureteroscopic Treatment of Urolithiasis

Start date: May 2024
Phase: Phase 2
Study type: Interventional

The purpose of the study is to investigate whether the use of gentamicin-based irrigation fluid during ureteroscopy decreases the risk of UTIs and other post-operative infections after surgery.

NCT ID: NCT06003348 Recruiting - Clinical trials for Calcium Phosphate Kidney Stones

Hydroxycitrate: A Novel Therapy for Calcium Phosphate Urinary Stones

Start date: December 13, 2023
Phase: Phase 4
Study type: Interventional

This study tests whether hydroxycitrate, a molecule closely related to citrate, can reduce calcium phosphate stone recurrence.

NCT ID: NCT05872230 Recruiting - Nephrolithiasis Clinical Trials

Massage Percussion for Passage of Urolithiasis Fragments After Ureteroscopy.

Start date: February 1, 2024
Phase: N/A
Study type: Interventional

Flexible ureteroscopy is characterized as first-line therapy for renal stones < 2 cm in size. Stones are commonly treated with dusting or fragmentation techniques which requires passage of stone fragments after surgery. Quoted stone free rate after flexible ureteroscopy is approximately 40-60% with a dusting technique. Residual fragments are often under 1mm in size and can layer in the lower pole of the kidney, complicating spontaneous stone passage. Improving the stone free rate after surgery decreases the need for secondary surgeries and decreases risk of future stone events. Numerous techniques have been proposed to increase stone passage including positional changes and percussion therapy. To date, there is overall limited data a lack of techniques that can be readily available in the outpatient setting, easily added to scheduled appointments, reproducible results and well tolerated by patients.

NCT ID: NCT05861024 Completed - Child, Only Clinical Trials

Urinary Calculi After Bladder Augmentation in Children

LITAVPED
Start date: November 20, 2022
Phase:
Study type: Observational

The goal of this observational study is to analyse the occurence of urinary calculi after bladder augmentation in children: - location of the calculi (kidney or bladder) - type of bladder augmentation with higher rate of urinary calculi and why - Find risk factors of urinary calculi in bladder augmentation (age, sex, other bladder procedures..)

NCT ID: NCT05759767 Active, not recruiting - Pediatric Disorder Clinical Trials

The Efficacy and Safety of Medical Expulsive Therapy After Extracorporeal Shock Wave Lithotripsy (ESWL) in Pediatric Urolithiasis

Start date: February 1, 2021
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the clinical efficacy and safety of MET after ESWL in pediatric urolithiasis.

NCT ID: NCT05712785 Recruiting - Urinary Calculi Clinical Trials

Shuotongo Ureteroscopy for Upper Urinary Tract Stones

SFUUTS
Start date: January 1, 2020
Phase: N/A
Study type: Interventional

The purpose of this study is to use the Shuotong ureteroscopy for surgical treatment of patients with upper urinary tract stones, taking advantage of the fact that the Shuotong mirror can be used for simultaneous lithotripsy and stone removal, thus maximizing the discharge of stones from the body and improving the stone removal rate.

NCT ID: NCT05707988 Not yet recruiting - Urolithiasis Clinical Trials

Kidney Stone Calculator

KSC
Start date: February 2023
Phase:
Study type: Observational

Urolithiasis is a frequent pathology, for which flexible ureteroscopy with endocorporeal laser lithotripsy has become the most frequently used surgical treatment. This procedure is limited to 90 minutes and will depend mainly on the total lithiasis volume. Knowing the duration of lithotripsy before the operation would allow to foresee situations of iterative procedures and to improve the patient's path (ambulatory or conventional surgery, work stoppage, optimization of operating times and operating room occupation times). "Kidney Stone Calculator" is a free tool capable of providing a calculi volumetry and predicting the duration of endocorporeal laser lithotripsy. The main objective of this study would be to evaluate the performance of the Kidney Stone Calculator in estimating the duration of laser lithotripsy during flexible ureteroscopy for renal calculi, by analyzing the agreement between the estimated and actual lithotripsy durations, evaluated by an intraclass correlation coefficient and its 95% confidence interval Eligible patients will be those scheduled for flexible ureteroscopy for renal calculi described on a non-injected abdominopelvic scan. A total of 240 patients over a 15-month inclusion period is planned, with a follow-up time of 3 months.

NCT ID: NCT05701098 Recruiting - Urolithiasis Clinical Trials

SOUND Pivotal Trial - (Sonomotion stOne comminUtion resoNance ultrasounD)

SOUND
Start date: October 9, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to test the Break Wave™ system in patients with upper urinary tract stones. The main question it aims to answer is whether the device is safe and effective in fragmenting (breaking) stones. Participants will a) undergo the Break Wave™ procedure, b) have a telehealth visit at 2 weeks, and c) return for an imaging study at approximately 10 weeks post-procedure.

NCT ID: NCT05634434 Recruiting - Renal Stone Clinical Trials

Uric Acid Based Renal Stones: Clinical, Metabolic and Genetic Characterization

Start date: October 1, 2021
Phase:
Study type: Observational

- Reporting prevalence of uric acid based renal stones among patients with nephrolithiasis admitted to Mansoura Urology and Nephrology center (MUNC). - Furthermore, identification of monogenic and polygenic uric acid stone formers. - Identification of factors associated uric acid stone recurrence as well as determinants of laterality in patients with uric acid based renal stones

NCT ID: NCT05627622 Recruiting - Urinary Tract Stone Clinical Trials

Effectiveness of WhatsApp Education and Support Messages for Urolithiasis Prevention

StoneApp
Start date: January 1, 2021
Phase: N/A
Study type: Interventional

Kidney and ureteral stones are a common problem in primary care practice with increasing prevalence over the last few decades. Prevention of recurrent stones (which are usually composed primarily of calcium oxalate) is aimed at decreasing the concentrations of the lithogenic factors. There are several metabolic and dietary treatable components. In all patients with urolithiasis, adequate fluid intake and lower body mass index are key components to reducing the risk of recurrent stones. For most patients, additional beneficial dietary modifications are increasing intake of fruits and vegetables which are rich in potassium, and reducing intake of candies and sweetened juices which are rich in sucrose and fructose. In addition, for patients who have been prescribed medications, adherence to medication may become an important issue over the long term. Mobile technology has the potential to optimize health care and patient's adherence, especially through personal education and dissemination of health information. One of the most common technologies available on mobile is the WhatsApp Messenger® application. WhatsApp is a freeware messaging service; it allows streamlining patient-provider communication via text and voice messages, video clips and images. The research hypotheses are, first, that use of WhatsApp to disseminate information regarding stones preventive measures will have a substantial positive effect on follow-up compliance and on patient's adherence to the preventive measures. Second, the investigators expect reduction in cumulative stone recurrence rate.