Type 2 Diabetes Clinical Trial
— PenDaNtOfficial title:
Effectiveness & Safety of Perfenidone in Type 2 Diabetic Patients With Diabetic Neuropathy: A Randomized Controlled Trial
The purpose of this study is to determine the effectiveness & safety of pirfenidone in type 2 diabetic patients with diabetic nephropathy
| Status | Recruiting |
| Enrollment | 60 |
| Est. completion date | March 9, 2025 |
| Est. primary completion date | March 9, 2025 |
| Accepts healthy volunteers | No |
| Gender | All |
| Age group | 30 Years to 65 Years |
| Eligibility | Inclusion Criteria: - Diabetic Nephropathy Stage 3 (eGFR 30-59 mL/min/1.73m2) Type 2 Diabetes HbA1c <7.5% Patient taking ACEi/ARB for at least 3 months BP <140/90 Exclusion Criteria: - History of photosensitivity rash History of decompensated liver or cardiac disease History of urinary tract infection Pregnancy or lactation History of nephrotoxic drugs or hakeem medication Polycystic kidney disease History of autoimmune disease History of hypersensitivity to study drugs |
| Country | Name | City | State |
|---|---|---|---|
| Pakistan | King Edward Medical University | Lahore | Punjab |
| Lead Sponsor | Collaborator |
|---|---|
| Sidrah Lodhi |
Pakistan,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | 15% improvement in eGFR | 15% improvement in eGFR | 6 months | |
| Secondary | Safety - Adverse Effects of Drugs | Adverse Effects of the drugs | 6 months |
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