Type 2 Diabetes Clinical Trial
Official title:
Dynamic Responsiveness of Insulin Secretory Parameters to Sitagliptin and Glimeperide Administration in Subjects With Type 2 Diabetes Mellitus: An Open Label Study
A multi-year clinical study to improve tools for measuring the function of insulin-producing beta cells in people with type 2 diabetes mellitus.
A three-year observational study to standardize the meal tolerance and maximal stimulation
tests for measuring beta cell function in the clinical setting. It also aims to improve
methods for the early prediction of the long-term response to an intervention and for
identification of patients at risk for rapid beta cell function deterioration, thereby
enabling future clinical studies that examine diabetes progression.
The objective of this protocol is to establish the dynamic responsivity of the methods to
treatment with glimerpiride or sitagliptin.
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Allocation: Non-Randomized, Intervention Model: Parallel Assignment, Masking: Open Label
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