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DPP-4 Inhibition, Incretins and Islet Function — CODI24  

Type 2 Diabetes Clinical Trial

Official title:
Comparison of Three DPP-4 Inhibitors on 24 Hour Blood Glucose, Incretin Hormones and Islet Function in Patients With Type 2 Diabetes

Clinical Trial Summary

Hypothesis is that DPP-4 inhibition affects glucose levels through changes in incretin and islet hormones. The study examines this in relation to breakfast, lunch and dinner over an entire 24h study period by the use of three different DPP-4 inhibitors and placebo.

Clinical Trial Description

The study is a single-center study with a cross-over design to examine glycemia, incretin hormones and islet hormones over a 24h study period with standardized breakfast, lunch and dinner after administration of placebo, saxagliptin, vildagliptin or sitagliptin. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02089438
Study type Interventional
Source Lund University
Contact
Status Completed
Phase Phase 4
Start date May 2014
Completion date August 2017
View Details
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