Type 2 Diabetes Clinical Trial
Official title:
Can we Screen Type 2 Diabetes on the 2nd Day After Delivery in Women Who Had Gestational Diabetes Mellitus?
Gestational diabetes mellitus (GDM) complicates 5 to 30 % of pregnancies. GDM is defined as
hyperglycemia with onset or first recognition during pregnancy. Because it is a forerunner of
type 2 diabetes mellitus (T2DM), professional associations recommend T2DM postpartum
screening (T2DM-pPS) at 6 weeks/6 months post delivery, using a 75g oral glucose tolerance
test (OGTT).
However, less than a quarter of these women are screened. This recommendation has failed for
multiple reasons; the most important being that busy new mothers must deal with the major
inconveniences of returning to a sampling center for a 2h testing session, bringing baby
along or paying for a sitter, transportation, parking… A mother-friendly solution is direly
needed.
The investigators hypothesize that, in these women, results of an OGTT performed after
delivery on the last day of their hospital stay (OGTT-1) will predict results of the
recommended OGTT (OGTT-2) at 6 weeks/6 months postpartum.
The main aim of our project is to determine the optimal cut-off value for the 2h glucose
result during OGTT-1 in order to predict abnormal glucose tolerance status at OGTT-2 (the
gold standard), in the same woman.
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