Type 2 Diabetes Clinical Trial
Official title:
EFFECT OF PARICALCITOL (ZEMPLAR) ON ENDOTHELIAL FUNCTION AND INFLAMMATION IN TYPE 2 DIABETES AND CHRONIC KIDNEY DISEASE
The purpose of this research study is to study the effects of paricalcitol on endothelial
function and inflammation, cardiovascular risk factors which are associated with patient
populations that have Type 2 diabetes and Stage 3 and 4 Chronic Kidney Disease (CKD).
Hypothesis 1: The state of CKD is associated with oxidative stress and inflammation and
impaired post ischemic endothelium dependent flow mediated vasodilation which may contribute
to atherogenesis.
Hypothesis 2: The administration of paracalcitol to patients with CKD will suppress
oxidative stress and inflammation and improve endothelial function and thus contribute to an
anti-atherogenic action.
n/a
Allocation: Randomized, Intervention Model: Single Group Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Diagnostic
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