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NCT00786721 Clinical Trial

Mitochondria and Metabolic Syndrome in a Southern California Chinese Cohort

Type 2 Diabetes Mellitus Clinical Trial

Official title:
Diffuse Optical Spectroscopy Measurement Technique is Helping Develop More Effective Diagnostic Tools and Therapeutic Regimes for Diabetes, Metabolic Syndrome and Other Mitochondrial Diseases Some Time in the Future

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT00786721
Other study ID # 20022608.
Secondary ID
Status Completed
Phase
First received
Last updated
Start date November 2006
Est. completion date August 2010

Study information
Verified date October 2022
Source University of California, Irvine
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

There has been increasing support for our hypothesis that mitochondrial dysfunction plays an important role in the etiology of Type 2 Diabetes Mellitus and the overlapping Metabolic Syndrome.

Description:

Once the mitochondrial defect(s) of these subjects has been defined, the data will be used to develop two non-invasive screening tools to detect mitochondrial defects in Diabetes Mellitus and Metabolic Syndrome patients. The device call Diffuse Optical Spectroscopy develope at Beckman Laser Instituteis is non-invasive measurement technique, to measure the properties of the muscle tisuue and vascular activity (calf, bicep, or the brain)to evaluate the patient's metabolic status and and to assess muscle mitochondrial OXPHOS function.

Recruitment information / eligibility
Status Completed
Enrollment 9
Est. completion date August 2010
Est. primary completion date August 2010
Accepts healthy volunteers No
Gender All
Age group N/A and older
Eligibility Inclusion Criteria: - Chinese descent and have been clinically diagnosed with diabetes mellitus (DM) or have met the study criteria for metabolic syndrome (MS). Exclusion Criteria: - non chiness descent

Study Design

Related Conditions & MeSH terms

Intervention

Device:
• Diffuse Optical Spectroscopy
muscle properties scanning

Locations
Country Name City State
United States Beckman Laser Institute Medical clinic Irvine California

Sponsors (2)
Lead Sponsor Collaborator
University of California, Irvine Beckman Laser Institute University of California Irvine

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary Near Infrared Spectroscopy to assess muscle mitochondrial OXPHOS function. 4 weeks
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