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Clinical Trial Summary

The study aims to obtain a local control rate in patients with lateral pelvic relapses of gynecologycal cancers previously irradiated. High LET (Linear Energy Transfer) particles as carbon ions can guarantee a biologic advantage compared to photons in radioresistant neoplasms, given to their higher biological efficacy (RBE).


Clinical Trial Description

Primary aim: estimate the effect, in terms of clinical response, of carbon ion treatment (CIRT) in patients with lateral pelvic recurrences of gynecological malignancies. Secondary aims: 1. To describe the safety profile of carbon ion therapy. 2. To estimate the effect, in terms of survival, of carbon ion treatment ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05457595
Study type Interventional
Source CNAO National Center of Oncological Hadrontherapy
Contact Amelia Barcellini, MD
Phone 390382075501
Email amelia.barcellini@cnao.it
Status Recruiting
Phase N/A
Start date February 24, 2021
Completion date February 25, 2025

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