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Treatment Outcome clinical trials

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NCT ID: NCT03375411 Withdrawn - Clinical trials for Coronary Artery Disease

First-in-Man Study: Safety and Efficacy of INC-1 Bare Metal Stent in the Novo Coronary Lesions.

Start date: December 30, 2017
Phase: N/A
Study type: Interventional

This is a First In Man study with the aim to know the safety and effectiveness of a novel bare metal stent (INC-1) in the treatment of de novo coronary lesions in patients with stable coronary angina and unique coronary lessions.

NCT ID: NCT03223142 Recruiting - Neoplasm Metastasis Clinical Trials

Standardization of Multi-modal Tumor Ablation Therapy System

SMTATS
Start date: July 2017
Phase: N/A
Study type: Interventional

This study will document for the safety and efficacy of image guided multi-mode precision ablation system (the combination of cryoablation and radiofrequency ablation) for the treatment of liver malignant, as well as provide the indicator of antitumor immune response for liver malignant in China.

NCT ID: NCT02993029 Recruiting - Treatment Outcome Clinical Trials

99Tc-MDP Treatment for Knee Osteoarthritis

Start date: September 1, 2017
Phase: N/A
Study type: Interventional

Osteoarthritis (OA) of knee is the most common form of arthritis in the world1e, and it has received growing attention in the society because of the increase of old age population, disabled people, and medical expenses from this disease. 99Tc-MDP is effective for rheumatoid arthritis. Therefore, the investigators try to investigate the effects of 99Tc-MDP treatment in patients with osteoarthritis of knee as compared with celecoxib.

NCT ID: NCT02816073 Completed - Clinical trials for Diabetic Retinopathy

Pattern Scanning Laser Pan-retinal Photocoagulation in Proliferative Diabetic Retinopathy

Start date: December 2012
Phase: N/A
Study type: Interventional

A randomized study to assess the safety and efficacy of single-session pan-retinal photocoagulation (PRP) using Pattern Scan Laser (PASCAL) in proliferative diabetic retinopathy (PDR) - 1,700 shots vs 2,500 shots

NCT ID: NCT02524912 Active, not recruiting - Quality of Life Clinical Trials

Methadone Maintenance Outcome Study in Taiwan: 5-year Follow-up

Start date: April 2015
Phase: N/A
Study type: Observational [Patient Registry]

Methadone maintenance treatment (MMT) has been one of the most effective treatment choices for opioid addicts to reduce their heroin use, criminality and spread of HIV. In Taiwan, MMT has been introduced since 2006. To date, more than 30,000 opioid addicts have ever participated in MMT, but only around 10,000 retains in treatment. Outcomes of the ever-treated MMT patients remain unclear. It is crucial to trace the opioid addicts' treatment career, outcomes and unmet treatment needs for the service providers to modify treatment strategy to help these individual to maintain abstinence. Moreover, understanding of the determinants for these subjects' long-term outcomes is important for policy makers to implement realistic policies to motivate the service providers and patients. From the results of previous research, the research team found that early dropout, defined as stayed in-treatment less than one month, of MMT participants were 14.4%. The rate of maintaining in treatment at 3rd , 6th, and 12th month were 65.7%、51.3% and 33.8%, respectively. Average treatment days for 12-month is 186.9±141.2. This result showed that the effectiveness of the MMT was varied among different facilities. On the other hand, the quality of the MMT can be improved largely through different dimensions. Besides, if one participant can enhance its motivation in staying in-treatment, it could reduce 15% early dropout. Above all, the result also showed that though the quality of life was recorded as improved after MMT, it appeared to be significantly lower than their healthy counterparties. The assessments of health outcomes after participating MMT are rare, but in need. It is necessary to make some modification to improve the effectiveness. Moreover, the evaluation of the needs shall not limit to patients, but also extend to their family members. Therefore, in this study, the research team plans to probe the dimensions from physical, psychiatric, to social conditions by assessing patients and their family members after treated by MMT for five years. The research team would like to know more about the outcomes of those who attended MMT five years ago, their physical and mental health conditions, also health status of their family members.

NCT ID: NCT02417194 Recruiting - Clinical trials for Carcinoma, Renal Cell

Prognostic Significance of Preoperative Hemoglobin A1c (HbA1c) in Renal Cell Carcinoma

Start date: April 2015
Phase: N/A
Study type: Observational [Patient Registry]

The effect of preoperative glycemic control measured by HbA1c on renal cell carcinoma (RCC) outcome remains controversial. Thus, the investigators aim to examine the association of preoperative glycemic control with oncologic outcomes after radical or partial nephrectomy. The investigators will prospectively collect the relevant data including preoperative HbA1c in 238 patients of RCC patients undergoing nephrectomy. The associations between clinical variables and risk of adverse pathological features and disease recurrence will be tested using a multivariate logistic regression and multiple Cox-proportional hazards model, respectively.

NCT ID: NCT01364649 Completed - Treatment Outcome Clinical Trials

Vortioxetine (Lu AA21004) 10 and 20 mg for Treatment of Major Depressive Disorder With Sexual Dysfunction

Start date: June 2011
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the effects of Vortioxetine (Lu AA21004), once daily (QD), compared with escitalopram on sexual functioning.

NCT ID: NCT01235104 Active, not recruiting - Urolithiasis Clinical Trials

Impact of Total Nephrectomy on Patients With Kidney Stone

Start date: January 2001
Phase: N/A
Study type: Observational

The aim of this study is to investigate the outcomes of total nephrectomy on patients with kidney stone disease.

NCT ID: NCT01183936 Completed - Surgery Clinical Trials

Trial of Surgical Excision Margins in Thick Primary Melanoma

Start date: January 1992
Phase: N/A
Study type: Interventional

Objectives: The purpose of this study was to assess the effects of an excision margin of 2 cm versus 4 cm for patients with primary cutaneous malignant melanoma (CMM). Study hypothesis: The hypothesis is that there is no difference between the two treatment arms measured as overall survival and recurrence free survival.

NCT ID: NCT00845078 Withdrawn - Radiotherapy Clinical Trials

Prospective Outcomes After Reconstruction and Radiotherapy for Breast Cancer

Start date: December 2008
Phase: N/A
Study type: Observational

This study examines the aesthetic outcomes of breast reconstruction after mastectomy for breast cancer in patients who require post-mastectomy radiation treatment. Patients will undergo autologous tissue breast reconstruction either in immediate fashion, prior to radiation treatment, or in delayed fashion, after radiation treatment. Both approaches are acceptable and are practiced clinically. this will be an observational prospective cohort study. The investigators hypothesize that immediate autologous reconstruction patients who undergo subsequent radiation therapy have equivalent aesthetic outcome when compared to those in whom reconstruction is delayed until after radiation, with the additional benefit of avoiding the psychological side effects of breast amputation.