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Treatment Adherence clinical trials

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NCT ID: NCT05719675 Completed - Quality of Life Clinical Trials

Healthcare Intervention Program on Treatment Adherence in People With Newly Diagnosed Type 2 Diabetes Mellitus.

Start date: March 1, 2023
Phase: N/A
Study type: Interventional

Type 2 Diabetes Mellitus (T2DM) is a group of metabolic disorders characterized by hyperglycemia in the absence of treatment, positioned in the first places of prevalence and mortality in the Mexican population. Adherence to treatment is a central element to prevent complications of the disease, where the active participation of the patient in his or her treatment is fundamental. Despite institutional healthcare efforts to promote this element, there is no clarity in the Clinical Practice Guidelines aimed at the attention of people with T2DM on how to achieve it. The aim of this project will be to evaluate the effect of an intervention based on Contingency Behavior Analysis on treatment adherence, quality of life and glycemic level in people with newly diagnosed T2DM. Pre-experimental design with pretest and posttest measurements. The Dependent Variable will be an intervention based on Contingency Behavior Analysis. The Independent Variables will be adherence to treatment, quality of life and glycemic level. The power calculation suggests an n = 38, using sequential non-probability sampling. People older than 18 years with less than 5 years of T2DM diagnosis will be included. Pretest and posttest differences, effect size and correlations between measurement variables will be analyzed. It is expected that the intervention based on Contingency Behavior Analysis will encourage the active participation of people with T2DM, improving their adherence to treatment, glycemic level and quality of life. Considering that the Clinical Practice Guidelines emphasize the importance of therapeutic adherence through the active participation of the patient and his/her environment, it is expected that this project will provide the tools for behavioral change that so far are not included in public health in Mexico.

NCT ID: NCT05576701 Completed - Treatment Adherence Clinical Trials

Laughter Therapy Application in Hemodialysis Patients

Start date: August 1, 2022
Phase: N/A
Study type: Interventional

Background: A randomized controlled study was conducted on the effects of laughter therapy on increasing the acceptance of the disease, compliance with treatment and comfort levels in patients receiving hemodialysis treatment. Materials and methods: The study was conducted with 42 (experimental group=21, control group=21) patients treated in the hemodialysis unit. Eight sessions of laughter yoga were applied to the hemodialysis patients in the experimental group for four weeks, two days a week. Data were used on the Patient Information Form, the Acceptance Scale, the End Stage Renal Failure - Compliance Scale, and the Hemodialysis Comfort Scale.

NCT ID: NCT05260203 Completed - Multiple Myeloma Clinical Trials

MargheRITA (Remote Intelligence for Therapeutic Adherence)

MargheRITA
Start date: June 4, 2022
Phase: N/A
Study type: Interventional

It is essential to improve clinical efficiency and management of hematological and oncological patients treated on an outpatient basis. The most promising operative way to achieve this result is the development of tele-oncology platforms, that allow not only a telemedicine visit, but also the patient support in the daily management of the disease and related disorders, as well as treatments and their complications. In this perspective, the RITA communication platform should be able to support the patient, the caregiver, the physician and the general practitioner in the management of the disease and its treatments.

NCT ID: NCT05155774 Completed - Treatment Adherence Clinical Trials

Treatment Adherence With Twin-Blocks for Correction of Class II Malocclusion

Start date: December 1, 2018
Phase: N/A
Study type: Interventional

To compare the effect of two control intervals (once every 4th week or once every 6th week) on the wear time of a Twin Block removable appliance.

NCT ID: NCT05022706 Completed - Treatment Adherence Clinical Trials

Pilot Study of a Transition Intervention for ALWH

PASEO
Start date: October 7, 2019
Phase: N/A
Study type: Interventional

The investigators will conduct a pilot study of a community-based intervention designed to improve outcomes among adolescents living with HIV (ALWH) transitioning to adult HIV care in Lima, Peru. The investigators will enroll adolescents transitioning to adult HIV care, either due to a recent diagnosis or having aged out of their pediatric clinic. ALWH previously lost from care during the transition process will also be invited to participate. The nine-month intervention will consist of (1) logistical, adherence and social support delivered by entry-level health workers who will accompany adolescents during their transition to adult HIV care and (2) group sessions to improve health-related knowledge, skills, and social support. The investigators will assess intervention feasibility and effectiveness in improving medication adherence, psycho-social outcomes, and transition readiness after 6, 9, and 12 months.

NCT ID: NCT04846166 Completed - Periodontitis Clinical Trials

I-Smads in Periodontitis

Start date: August 1, 2019
Phase:
Study type: Observational [Patient Registry]

Recently, it has been stated that Smads play an active role in all conditions where transforming growth factor-beta (TGF-β) is involved, including periodontal inflammation. This study aimed to examine the levels of TGF-β and inhibitor Smads in saliva and gingival crevicular fluid (GCF) in patients with Stage 3 Grade B periodontitis before and after non-surgical periodontal treatment. Twenty (20) stage 3 grade B periodontitis and 20 periodontally healthy individuals were included in the study. Clinical periodontal measurements were recorded; periodontitis patients received non-surgical periodontal treatment, and GCF and saliva samples were obtained at baseline and one month after treatment. TGF-β, Smad6, and Smad7 were determined by ELISA.

NCT ID: NCT04573465 Completed - Treatment Adherence Clinical Trials

Pilot Evaluation of Peer-support Coaching to Increase Adherence to Online Self-help for College Mental Health

Start date: September 28, 2020
Phase: N/A
Study type: Interventional

This study aims to test if coaching can improve program adherence to an online mental health program in college students if delivered by undergraduate peers. Participants will be randomly assigned to either receive phone coaching, text message coaching, or no coaching. It is hypothesized that participants who receive phone coaching will exhibit greater adherence to the provided online mental health program than participants who receive text message coaching or no coaching.

NCT ID: NCT04464421 Completed - Opioid-use Disorder Clinical Trials

SMART Trial Efficacy Study

Start date: August 17, 2020
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the efficacy of two different interventions for medication-assisted treatment (MAT) adherence: Contingency Management (CM) and Brief Motivational Intervention plus Substance Free Activities Session plus Mindfulness-Based Adherence Promotion (BMI+SFAS+MBAP). If the interventions are efficacious, they will be used in a larger trial with a SMART (Sequential Multiple Assignment Randomized Trial) design.

NCT ID: NCT04377321 Completed - Treatment Adherence Clinical Trials

Colchicine Has Anti-diabetic Effect

Start date: October 10, 2019
Phase:
Study type: Observational [Patient Registry]

Colchicine has antidiabetic effect and may be an option for type 2 diabetes management

NCT ID: NCT04323215 Completed - Childhood Obesity Clinical Trials

Evaluation of a Digital Childhood Obesity Treatment

Start date: September 1, 2018
Phase:
Study type: Observational

This study aims to evaluate if a web-based digital support system aiming to replacing or complement standardized pediatric behavioural obesity treatment. The hypothesis is that a digital system of communication between the family and the clinic can generate improved treatment results (change in BMI SDS) and reduce the number of missed visits.