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Trauma clinical trials

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NCT ID: NCT03830008 Completed - Depression Clinical Trials

Scaling-up Psychological Interventions With Syrian Refugees in Switzerland

STRENGTHS_CH
Start date: December 21, 2018
Phase: N/A
Study type: Interventional

The current refugee crisis across the Middle East and Europe has large effects on individual refugees' psychological well-being, as well as on the healthcare systems of countries hosting refugees. For example, in Switzerland patients sometimes have to wait up to 12 months for the specific psychological treatment due to a lack of specialists. To address this problem the WHO has developed Problem Management Plus (PM+), a brief (five sessions), low-intensity psychological intervention, delivered by paraprofessionals, that addresses common mental disorders in people in communities affected by adversity. The feasibility of PM+ has never been examined in Switzerland before, this is the aim of the current pilot study.

NCT ID: NCT03809520 Recruiting - Trauma Clinical Trials

An Imaging Framework for Clinically Testing New Treatments to Prevent Post-traumatic OA

Start date: January 1, 2017
Phase: N/A
Study type: Interventional

The immediate goal of the proposed research is to test the value of a new low-cost, low-dose standing CT system for efficient early detection of both joint degeneration and elevated contact stress. The standing CT scanner holds promise for detecting arthritic changes earlier than other imaging modalities because of the combination of its 3D nature and ability to image joints in a weight-bearing pose. A secondary goal of the proposed research is to enable predictive models for osteoarthritis risk based on measures of post treatment contact stress, both to inform treatment and so that new interventions can be tested in a manner incorporating risk stratification.

NCT ID: NCT03789396 Completed - Critical Illness Clinical Trials

Pilot Study of Targeted Normoxia in Critically Ill Trauma Patients

Start date: January 1, 2018
Phase:
Study type: Observational [Patient Registry]

The objective of this study is to conduct an observational pre/post study to evaluate the clinical impact oxygen guideline implementation on oxygen utilization and oxygenation in critically ill trauma patients.

NCT ID: NCT03781817 Terminated - Trauma Clinical Trials

Intranasal Versus Intravenous Ketamine for Procedural Sedation in Children With Non-operative Fractures

Start date: September 9, 2019
Phase: Phase 4
Study type: Interventional

This a randomized clinical trial involving children with non-operative fractures presenting the emergency department randomized either to intranasal or intravenous ketamine.

NCT ID: NCT03779243 Completed - Trauma Clinical Trials

Treatment for Sleep Disturbance in Orthopaedic Trauma Patients

Start date: January 7, 2019
Phase: N/A
Study type: Interventional

The purpose of the study is to test the efficacy of sleep treatment in human patients following traumatic injury. Specifically, the study will determine if treatment consisting of melatonin and education related to sleep habits are effective in treating sleep disturbance and improving sleep quality in Orthopaedic trauma patients. We hope to learn if melatonin and sleep education effectively improve sleep following traumatic injury, and improve outcomes.

NCT ID: NCT03778307 Recruiting - PTSD Clinical Trials

Key Dimensions of PTSD and ED

Start date: November 20, 2019
Phase:
Study type: Observational

This study will test whether endothelial dysfunction could be the early subclinical mechanism by which posttraumatic stress disorder (PTSD) increases cardiovascular disease (CVD) risk, and whether posttraumatic fear-a key component of PTSD-or another PTSD dimension could be the target to offset that risk. The results of this study may help trauma-exposed individuals who are at risk of having CVD events.

NCT ID: NCT03765866 Completed - Trauma Clinical Trials

Rotational Thromboelastometry Activated Transfusion In Trauma Trial

ROTATE-IT
Start date: May 2016
Phase: N/A
Study type: Interventional

This is a randomized controlled trial to compare viscoelastic (VE) guided resuscitation to fixed-ratio resuscitation in trauma patients with hemorrhagic shock on the utilization of blood products, effects on coagulation and inflammatory mediators, and how these strategies affect post resuscitation adverse events.

NCT ID: NCT03756545 Completed - PTSD Clinical Trials

Neurobehavioral Moderators of Post-traumatic Disease Trajectories

Start date: January 20, 2015
Phase:
Study type: Observational [Patient Registry]

The research goal is to uncover the neurocognitive moderators of PTSD trajectories, by documenting clinical symptoms, cognitive functioning, and brain structure and function, one-, six- and fourteen months following a traumatic event, in a large population of survivors at initial high risk for PTSD.

NCT ID: NCT03751189 Completed - Trauma Clinical Trials

Role of Overjet and Trauma in Libyan Children

Start date: May 10, 2016
Phase:
Study type: Observational

Traumatic dental injuries are one of the commonly encountered dental emergencies. Missing anterior tooth in children due to any injury can be a source of considerable physical and psychological discomfort for the child. These consequences also have significant impact on parents, who are generally concerned with esthetic and economic aspects of this problem. It varies from small crack in the enamel to complete loss of the tooth. Injury to children teeth can be both painful and traumatic to the children

NCT ID: NCT03696563 Not yet recruiting - Trauma Clinical Trials

FreeO2 PreHospital - Automated Oxygen Titration vs Manual Titration According to the BLS-PCS

Start date: September 2021
Phase: N/A
Study type: Interventional

Evaluation of automated oxygen titration in comparison with manual adjustment oxygen in the out-of-hospital setting by paramedics.