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Toothache clinical trials

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NCT ID: NCT00720057 Completed - Toothache Clinical Trials

Assessing the Analgesic Efficacy of Naproxen Sodium in Postsurgical Dental Pain.

Start date: June 2008
Phase: Phase 3
Study type: Interventional

To evaluate the analgesic efficacy of a single, oral dose of a naproxen sodium extended-release tablet, compared to placebo in postsurgical dental pain.

NCT ID: NCT00694369 Completed - Clinical trials for Postoperative Dental Pain

A Study to Asses the Effect of MK0663 in the Treatment of Patients With Postoperative Dental Pain (0663-092)

Start date: June 2008
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the pain relieving effect of different doses of MK0663 with placebo and other pain relievers/analgesics in patients with postoperative dental pain. Pain intensity and relief will be measured by the total pain relief score (TOPAR) and patient evaluation.

NCT ID: NCT00663767 Completed - Dental Pain Clinical Trials

A Study of ARRY-371797 in Subjects Undergoing Third Molar Extraction

Start date: April 7, 2008
Phase: Phase 2
Study type: Interventional

This is a Phase 2 study designed to test the ability of investigational study drug ARRY-371797 to reduce pain in a postoperative pain model (third molar extraction), and to further evaluate the drug's safety. Approximately 250 subjects from the US will be enrolled in this study.

NCT ID: NCT00631111 Completed - Pain Clinical Trials

Study Evaluating the Efficacy of an Ibuprofen Effervescent Tablet in the Treatment of Post-Surgical Dental Pain

Start date: November 2007
Phase: Phase 3
Study type: Interventional

Evaluation of the efficacy and safety of a single dose of an ibuprofen effervescent tablet in the treatment of pain following third molar extraction in comparison to single doses of placebo, standard ibuprofen tablets, and effervescent aspirin plus vitamin C tablets.

NCT ID: NCT00574015 Completed - Toothache Clinical Trials

The Comparison of Supraperiosteal Nerve Block With Opiate Analgesia in Alleviating the Pain of Toothache

Start date: December 2007
Phase: Phase 4
Study type: Interventional

This study will compare the degree of pain control provided by two techniques for persons with toothache in an emergency department. The two techniques include; - standard oral narcotic pain medication - numbing the tooth with local anesthetic by needle injection

NCT ID: NCT00542035 Completed - Dental Pain Clinical Trials

A Study of ARRY-371797 in Subjects Undergoing Third Molar Extraction

Start date: November 11, 2007
Phase: Phase 2
Study type: Interventional

This is a Phase 2 study designed to test the ability of investigational study drug ARRY-371797 to reduce pain either perioperatively or postoperatively in a third molar extraction pain model, and to further evaluate the drug's safety. Approximately 150 subjects from the US will be enrolled in this study.

NCT ID: NCT00474175 Completed - Toothache Clinical Trials

Benzocaine Gel Toothache Dose-Response Study

Start date: May 2007
Phase: Phase 4
Study type: Interventional

To evaluate the efficacy and safety of benzocaine gel products for the relief of toothache and to assess the subject's compliance with proposed label directions.

NCT ID: NCT00387140 Completed - Pain, Postoperative Clinical Trials

A Study to Evaluate the Safety and Efficacy of an Investigational Drug in the Treatment of Postoperative Dental Pain (MK-2295-005)

Start date: October 2006
Phase: Phase 2
Study type: Interventional

This study is being conducted to evaluate the safety and tolerability of the drug and to evaluate its efficacy compared to placebo and to ibuprofen in the treatment of postoperative dental pain in male patients.

NCT ID: NCT00281684 Completed - Toothache Clinical Trials

SB-705498 Dental Pain Study After Tooth Extraction

Start date: December 7, 2005
Phase: Phase 2
Study type: Interventional

This clinical trial is a multi centre, randomised, single-blind, parallel group, placebo-controlled, single oral dose study with a positive control arm. Patients previously scheduled for 3rd molar tooth extraction, who are otherwise healthy, will be recruited. Upon completion of surgery, e.g. prior to established pain, patients will be randomised to treatment (SB-706598, placebo or co-codamol) and dosed with the study medication

NCT ID: NCT00240864 Completed - Pain Clinical Trials

An Effectiveness and Safety Study of Acetaminophen 1000 mg and Ibuprofen 400 mg in Postoperative Dental Pain

Start date: n/a
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine the onset of pain relief from a single dose of acetaminophen and ibuprofen in subjects experiencing postoperative dental pain following the surgical extraction of at least three molars.