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NCT ID: NCT05883566 Completed - Dental Anxiety Clinical Trials

Comparison of Dental Pain Response in Children

Start date: May 1, 2023
Phase: N/A
Study type: Interventional

Study involves the observation of the child's behavior during a dental treatment procedure. This allows for the evaluation of the child's experience of pain and discomfort through their facial expressions, body movements, and vocalizations during the procedure.

NCT ID: NCT05808452 Completed - Self Medication Clinical Trials

AMO CROC Study: Self-medication and Dental Pain of Pulpal and Peri-apical Origin. Qualitative Study

AMO-CROC
Start date: January 30, 2023
Phase:
Study type: Observational

Adult patients with dental anxiety or phobia constitute a population for which access to dental care is difficult and this situation is often associated with am low socio-economic status. According to the literature, these patients avoid conventional care, make greater use of emergency services, and self-medicate when experiencing dental pain. Moreover, little is known in the literature about the use of self medication in France, although it is known that in the general population does self medicate a lot. The objective of this study is to better understand the self-medication behaviors of patients in order to improve their care. This work aim at characterizing a population of adults in need of treatment for dental pain of pulpal or periapical origin and anxious or phobic adults in need of for dental treatment under general anesthesia. Self-medication behaviors will be studied in qualitative research during recorded interviews.

NCT ID: NCT05761574 Completed - Pain Clinical Trials

A Study of an Acetaminophen/Naproxen Sodium Fixed Combination, Acetaminophen and Naproxen Sodium in Postoperative Dental Pain

Start date: May 22, 2023
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate how well a fixed combination of acetaminophen/naproxen sodium relieves postoperative dental pain compared with acetaminophen, naproxen sodium and placebo.

NCT ID: NCT05757648 Completed - Dental Pain Clinical Trials

Buffered Local Anesthetic

Start date: December 8, 2020
Phase: Phase 4
Study type: Interventional

The purpose of this research study is to compare responses in children during dental injections of local anesthetic (used for numbing), while children are under deep sedation (breathing on their own, often with a loss of consciousness). Two types of local anesthetic will be used--one will be buffered (by adding a salt solution to make it less acidic), while the other will be plain, without anything added. Previous studies have shown that the addition of the buffer solution can improve comfort during a dental injection.

NCT ID: NCT05485805 Completed - Clinical trials for Postoperative Dental Pain

A Study to Learn How Well a Single Dose of the Study Treatment Naproxen Sodium and Caffeine Combined in One Tablet (Fixed-dose Combination) Works to Relieve Pain After Dental Surgeries Compared to the Single Ingredients and to Placebo

Start date: September 21, 2022
Phase: Phase 3
Study type: Interventional

Researchers are looking for a better way to relieve pain in people, such as after dental surgery. Participants in this study, have had 3 or 4 third molars (cheek teeth) removed and subsequently have moderate to severe tooth pain. The study treatment naproxen sodium suppresses inflammatory pain by reducing inflammation. In the US, naproxen has been marketed since 1976, and naproxen sodium has been approved for over-the-counter (OTC) use since 1994 for the temporary relief of minor aches and pains. Caffeine, which is generally consumed as coffee, tea, or cocoa, has been shown to enhance the effect of various painkillers, and therefore is accepted as an additive. The main purpose of this study is to learn how well a fixed-dose combination of naproxen sodium and caffeine relieves pain compared to each single ingredient as well as to placebo in participants after molar removal. A placebo is a treatment that looks like a medicine but does not have any medicine in it. To answer this, the researchers will compare the amount of pain decrease over 8 hours in participants who received a single dose of either: - 1 fixed-dose tablet of naproxen sodium/caffeine - 2 fixed-dose tablets of naproxen sodium/caffeine - naproxen sodium only - caffeine only - or placebo The study participants will be randomly (by chance) assigned to one of the five treatment groups. They will take a single dose of two tablets by mouth within 4.5 hours after the surgery. If there is no pain relief within 2 hours after intake, other painkillers may be given.

NCT ID: NCT05369936 Completed - Dental Anxiety Clinical Trials

Pain Perception: on Relationships Between Dental Anxiety and Olfaction

Start date: March 12, 2018
Phase: N/A
Study type: Interventional

the objective of this study is to evaluate the ability of olfaction in obtaining positive emotional and behavioral responses toward dental anxiety and pain in patients undergoing different dental procedures.

NCT ID: NCT04949126 Completed - Dental Anxiety Clinical Trials

Self Medication in Odontology (AUDE)

AUDE
Start date: June 15, 2021
Phase:
Study type: Observational

To describe and understand the self-medication behaviours of a population of adults coming to the Clermont-Ferrand dentistry department for acute pain of pulpal origin and of a population of adults coming to the specific care unit of the Clermont-Ferrand dentistry department or the Riom hospital for treatment under general anaesthesia.

NCT ID: NCT04642404 Completed - Toothache Clinical Trials

CBD for Dental Pain

Start date: March 1, 2021
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to evaulate CBD as a therapeutic approach for dental pain. Eligible subjects presented with emergency dental pain will be give a single dose of Epidiolex (FDA-approved CBD) or placebo and will be monitored for 3 hours for pain symptoms and psychologic effects.

NCT ID: NCT04573608 Completed - Clinical trials for Patient Satisfaction

The Impact of Minimally Invasive Restorative Techniques on Dental Pain in Pregnant Women

Start date: January 10, 2019
Phase: Phase 2
Study type: Interventional

The aim of the present study was to compare the effectiveness of chemo-mechanical caries removal using Papacarie-Duo and Atraumatic Restorative Treatment (ART) in reducing dental pain in pregnant women.

NCT ID: NCT04571515 Completed - Pain Clinical Trials

Dose-Response Study of MR-107A-01 in The Treatment of Post-Surgical Dental Pain

Start date: September 29, 2020
Phase: Phase 2
Study type: Interventional

MR-107A-01 is being studied to investigate its efficacy, safety, and dose-response after dental surgery.