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Toothache clinical trials

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NCT ID: NCT02476422 Completed - Clinical trials for Post Operative Dental Pain

A Study to Assess the Efficacy and Tolerability of Diclofenac Potassium Soft Gelatin Capsules Compared With Ibuprofen Tablets in Patients With Moderate to Severe Postoperative Dental Pain

Start date: April 2015
Phase: Phase 3
Study type: Interventional

The study is designed to assess the efficacy and tolerability of diclofenac potassium soft gelatin capsules compared with ibuprofen tablets in patients with moderate to severe postoperative dental pain.

NCT ID: NCT02463552 Completed - Tooth Bleaching Clinical Trials

Naproxen on Tooth Sensitivity Caused by In-office Bleaching

Start date: May 2015
Phase: N/A
Study type: Interventional

This study aims to evaluate the effects of prior use of non-steroidal anti-inflammatory Naproxen on risk and level of tooth sensitivity caused by in-office bleaching procedures.

NCT ID: NCT02443207 Completed - Dental Caries Clinical Trials

Impact of Dental Pain on the Quality of Life

Start date: January 2013
Phase: N/A
Study type: Observational [Patient Registry]

The aim of the present study was to evaluate the perceived impact of dental caries and dental pain on oral health-related quality of life (OHRQoL) among preschool children and their families. A cross-sectional study was conduct with 843 preschool children in Campina Grande, Brazil. Parents/caregivers answered a questionnaire on socio-demographic information, their child's general/oral health and history of dental pain. The Brazilian version of the Early Childhood Oral Health Impact Scale was administered to determine the perceived impact of caries and dental pain on OHRQoL. Children have undergone an oral examination. Logistic regression for complex sample was used to determine associations between the dependent and independent variables (OR: odds ratio; α = 5%).

NCT ID: NCT02320708 Completed - Dental Pain Clinical Trials

Study of Acetaminophen (ACE) in Post-operative Dental Pain

Start date: December 31, 2014
Phase: Phase 2
Study type: Interventional

This is a dental pain study evaluating the efficacy and safety of a single dose of test acetaminophen (ACE) (1000 mg) compared to commercial acetaminophen (1000 mg), ibuprofen (IBU) (400 mg), and placebo over a 6 hour period. Subjects will undergo dental extraction of three or four third molars.

NCT ID: NCT02209181 Completed - Pain Clinical Trials

A Dental Pain Study to Test the Effectiveness of a New Pain Reliever Medicine

Start date: August 2014
Phase: Phase 2
Study type: Interventional

To assess the safety and effectiveness one dose of a new pain reliever medicine (JNJ-10450232 at either the 250 or 1000 mg strength) compared with placebo (sugar pill) or acetaminophen 1000 mg after surgical removal of third molars. The primary endpoint will evaluate pain relief effectiveness up to 6 hours after administration of the study drug.

NCT ID: NCT02161354 Terminated - Dental Pain Clinical Trials

Safety and Efficacy Study of NTC-510 to Treat Pain Following Dental Surgery of Third Molars

Start date: June 2014
Phase: Phase 2
Study type: Interventional

To evaluate the efficacy of a single dose NTC-510 or NTC-510A for dental pain following third molar extraction.

NCT ID: NCT02084511 Completed - Pain, Postoperative Clinical Trials

Effectiveness and Safety of Different Doses of BI 1026706 in Patients With Postoperative Dental Pain

Start date: March 2014
Phase: Phase 1
Study type: Interventional

To investigate the effectiveness of BI 1026706 powder for reconstitution of an oral solution compared to placebo and the relative effectiveness compared to Celecoxib.

NCT ID: NCT01982799 Withdrawn - Odontalgia Clinical Trials

Local Anesthesia and Analgesics in Endodontic Pain

LAAEP
Start date: February 2014
Phase: N/A
Study type: Interventional

For patients with a toothache, is pain relief after root canal procedure improved using long acting local anesthetic and analgesics? The purpose of this clinical trial is the investigate the effect of long acting local anesthetic with 1 of 4 oral medication groups, on post-operative endodontic pain.

NCT ID: NCT01960114 Completed - Dental Pain Clinical Trials

Study of Long-Acting Acetaminophen in Postoperative Dental Pain

Start date: October 2013
Phase: Phase 2
Study type: Interventional

The purpose of the study is to evaluate the efficacy and safety of acetaminophen ER 1500 mg (two 750 mg tablets) over 10 to 12 hours in the dental pain model following third molar extraction(s) and to evaluate the pharmacokinetics of acetaminophen ER 1500 mg (two 750 mg tablets) in a sub-group of subjects.

NCT ID: NCT01920386 Completed - Clinical trials for Acute Toothache Patients Above Moderate Pain After Teeth Extraction Surgery

Phase 3 Study of Tramadol Hydrochloride/Acetaminophen SR Tab. & Tramadol Hydrochloride/Acetaminophen Tab. in Acute Toothache Patients After Teeth Extraction Surgery

Start date: June 2013
Phase: Phase 3
Study type: Interventional

A randomized, double-blind, active-controlled, parallel, multicenter Phase 3 study of Tramadol hydrochloride/Acetaminophen SR Tab. & Tramadol hydrochloride/Acetaminophen Tab. in Acute Toothache Patients above Moderate Pain after Teeth Extraction Surgery.