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Tinnitus clinical trials

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NCT ID: NCT01261949 Completed - Tinnitus Clinical Trials

Combined Low Frequency Frontal and Temporal rTMS Treatment in Chronic Tinnitus

Start date: April 2009
Phase: N/A
Study type: Interventional

Transcranial Magnetic Stimulation is used to modulate the auditory neural pathways caused by hearing loss and leading to the phantom auditory perception of sound in the absence of an external or internal acoustic stimulus.

NCT ID: NCT01253616 Completed - Severe Tinnitus Clinical Trials

Proof-of-Concept Study Assessing VNS Paired With Tones for Tinnitus

Start date: December 2010
Phase: N/A
Study type: Interventional

This is a proof-of-concept study designed to provide feasibility information on the clinical use of vagus nerve stimulation (VNS) paired with tones for the treatment of severe tinnitus. The study is expected to give preliminary efficacy and safety information.

NCT ID: NCT01229709 Completed - Depression Clinical Trials

Mindfulness Based Tinnitus Reduction (MBTR): A Symptom Perception Shift Program

MBTR
Start date: January 2011
Phase: Phase 2
Study type: Interventional

This study is a randomized, controlled trial of Mindfulness Based Tinnitus Reduction (MBTR) vs. Treatment As Usual (TAU). This study aims to determine patient's benefit from participating in an 8-week MBTR program as measured by a reduction in clinical symptoms, if present, and a tinnitus symptom perception shift. Sixty-four tinnitus patients who have previously received Tinnitus Counseling (TAU) at the UCSF Audiology Clinic under the direction of Robert Sweetow, PhD will be invited to participate in the MBTR study. Subjects will be randomly assigned to the experimental and control groups of 32 each. All subjects will have received Tinnitus Counseling at least 6-months prior to entry into the study. Tinnitus symptom activity and discomfort as well as psychological outcomes will be assessed by self-report questionnaires. The primary outcome measure is the Tinnitus Handicap Inventory (THI) measuring tinnitus symptom severity. The secondary outcome measures include the Tinnitus Visual Analogue Scale (TVAS), the Symptom Checklist-90-Revised (SCL-90-R), Hamilton Anxiety and Depression Scale (HADS), and the Five Factor Mindfulness Questionnaire (FFMQ). In addition to tinnitus symptom severity, secondary outcome measures are used to measure change in mindfulness and other clinical symptoms such as anxiety and depression, if they exist. The experimental group will complete measures at pre-, post-, at 3-months and 12-months follow-up. A 12-month follow-up assessment will be conducted with the experimental group to identify any enduring effects of the treatment. The control group will fill out measures at pre-, post-, and 3-month time periods. The 12-month follow-up will be conducted with the experimental group only and will be the uncontrolled portion of the study. The purpose of this study is to 1) Design and execute an MBTR program for patients with tinnitus within the UCSF Department of Audiology. 2) Determine patient's benefit from participating in an 8-week MBTR program as measured by a decrease in tinnitus distress, and a reduction in clinical symptoms (i.e., depression, anxiety), if present. 3) Compare the responses on study measures to those of the control group. 4) Collect follow-up data at 6- and 12-months post intervention to assess enduring effects, if any, in the experimental group. 5) Use the data and patient feedback to modify UCSF's Audiology program and guide future programming in regards to the treatment and care of patients with tinnitus.

NCT ID: NCT01226108 Completed - Tinnitus Clinical Trials

The Akloma Tinnitus Patch in Patients With Manifested Tinnitus

Aktin
Start date: October 2010
Phase: N/A
Study type: Interventional

OBJECTIVES: Primary Objective The primary objective will be a decrease of inconvenience with at least 10% for at least 50% of the subjects. Secondary Objectives The secondary objective will be to: To evaluate if the patch can improve the tinnitus patient's quality of life and sleep quality. METHODOLOGY Study Design: An open safety and performance clinical investigation of the antinitus patch in patients with manifested tinnitus. Treatment Duration: 1 patch per day for 3 weeks Primary Endpoint: Tinnitus severity questionnaire (TSQ) Performance Parameters: Tinnitus severity questionnaire (TSQ) and numerical rating scale (NRS) measuring tinnitus annoyance. Quality of life and sleep quality Safety Parameters: Adverse Reactions

NCT ID: NCT01222507 Completed - Tinnitus Clinical Trials

Processing Speed as an Objective Measure of Tinnitus

BST
Start date: July 2010
Phase: N/A
Study type: Observational

The overall purpose of this research is to assess whether both the "60 second Brain Game" and the "Brain Speed Test" computer-based programs can be used as assessment tools for objectively defining the severity of the functional impact of tinnitus.

NCT ID: NCT01205919 Completed - Tinnitus Clinical Trials

Internet-based Guided Self-help for Chronic Tinnitus

TITUS
Start date: May 2010
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the efficacy of a cognitive behavioral guided self-help training provided via the internet on tinnitus distress in a German sample.

NCT ID: NCT01205906 Completed - Tinnitus Clinical Trials

Comparison of an Internet-based Guided Self-help and a Group Therapy for Chronic Tinnitus

MINT
Start date: May 2010
Phase: N/A
Study type: Interventional

The aim of this study is to compare the efficacy of an internet-based guided self-help training for chronic tinnitus with a well-established outpatient group therapy and a discussion forum group.

NCT ID: NCT01187251 Completed - Tinnitus Clinical Trials

Incidence of Tinnitus Amongst Teenagers and Young Adults mp3 Users

Start date: August 2009
Phase: N/A
Study type: Observational

The aim of this study is to compare the incidence of tinnitus between mp3 users and non-users, aged between 15 and 30 years old. 100 patients will be recruited in Valença secondary schools. High frequency audiometry and otoacoustic emissions will be performed.Tinnitus patients will complete the Tinnitus Handicap Inventory questionnaire.

NCT ID: NCT01177137 Completed - Subjective Tinnitus Clinical Trials

Tinnitus Retraining Therapy Trial

TRTT
Start date: July 2011
Phase: Phase 3
Study type: Interventional

The primary purpose of the Tinnitus Retraining Therapy Trial (TRTT) is to assess the efficacy of tinnitus retraining therapy (TRT) as a treatment for severe debilitating tinnitus. TRT is a non-medical intervention that uses directive counseling (DC) and sound therapy (ST)to habituate the patient's associated negative emotional reactions to tinnitus, its perception, and ultimately, its impact on the patient's life.

NCT ID: NCT01176734 Completed - Tinnitus Clinical Trials

The Treatment of Tinnitus With Transcutaneous Non-invasive Vagus Nerve Stimulation

Start date: January 2010
Phase: N/A
Study type: Interventional

The t-VNS STv3 device is a non-invasive, transcutaneous neurostimulator for influencing the afferent branches of the nervus vagus around the human ear. The clinical trial is designed as a a pilot study addressing the treatment of tinnitus with transcutaneous vagus nerve stimulation.