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Thyroid clinical trials

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NCT ID: NCT05699304 Completed - Thyroid Clinical Trials

Complications After Thyroid Surgeries: 10 Years' Experience

Start date: January 30, 2023
Phase:
Study type: Observational

Thyroidectomy is one of the commonest elective surgeries in surgical practice nowadays. It is associated with wide range of complications, from unnoticed events up to lifelong problems and even life-threatening complications. The most troublesome are bleeding, nerve injury and hypocalcemia. The current study was conducted to report the incidence and predictive factors for perioperative complications, aiming to point out preventive measures.

NCT ID: NCT05434715 Completed - Thyroid Clinical Trials

Evaluation of Minimal Invasive Thyroidectomy

Start date: March 1, 2021
Phase: N/A
Study type: Interventional

The goals of minimally invasive approaches are better cosmetic results with small neck scar, decreasing postoperative pain, and shortening of hospital stay periods without postoperative complications. The concept of surgical invasiveness cannot be limited to the length and site of the skin incision; it must be extended to all structures dissected during the procedure. Conventional thyroidectomy without raising subplatysmal flaps has proven to be effective in reducing postoperative pain and seroma

NCT ID: NCT05421559 Completed - Surgery Clinical Trials

Transection of Sternothyroid Muscle Increases the Rate of Exposure of the External Laryngeal Nerve During Thyroidectomy

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

The sternothyroid (ST) muscle is closely adherent to the thyroid gland with oblique insertion into the thyroid cartilage. EBSLN passes through the sternothyroid laryngeal triangle with a parallel course deep to the ST muscle. This study evaluates the transection of the sternothyroid muscle as a key step during thyroidectomy to increase the rate of exposure and visual identification of EBSLN compared to ST muscle retraction as a traditional technique.

NCT ID: NCT05323539 Completed - Thyroid Clinical Trials

Comparison of Thyroid Volumes in Patients With and Without Endometrioma

Start date: September 20, 2021
Phase: N/A
Study type: Interventional

The aim of our study is to evaluate whether there is a statistical difference between thyroid gland volume in patients with pathological diagnosis of endometriosis or endometrioma and in patients who underwent surgery for other gynecological reasons, and to reveal the presence of concomitant thyroid disease in these cases.

NCT ID: NCT05276271 Completed - Epilepsy Clinical Trials

The Effect of Levetiracetam on Lipid Profile in Children

Start date: October 1, 2020
Phase:
Study type: Observational

Levetiracetam is a widely prescribed antiseizure medication in epileptic children due to an estimated better safety profile and easy accessibility. There is limited and contradicting data about the effect of levetiracetam on serum lipid metabolisms, especially in epileptic children. The aim of our study was to evaluate the effect of levetiracetam therapy on lipid metabolism in euthyroid non-obese epileptic children. In this case-control study, the investigators recruited 37 epileptic children receiving levetiracetam monotherapy for at least 12 months and 54 healthy controls. All the participants were euthyroid and within normal nutritional status limits for their age. Fasting blood samples were obtained for serum thyroid-stimulating hormone (TSH), free triiodothyronine, free thyroxine, total cholesterol (TC), high-density lipoprotein (HDL), low-density lipoprotein (LDL), triglycerides, Triglyceride/HDL Index, uric acid, CRP, and transaminases at the administration. The investigators would like to show if epileptic children with levetiracetam monotherapy are susceptible to lipid metabolism alterations.

NCT ID: NCT04860622 Completed - Pregnancy Related Clinical Trials

Normal Range of TSH and FT4 in Pregnancy

NRTSHTURKEY
Start date: April 1, 2021
Phase:
Study type: Observational [Patient Registry]

Physiological changes necessitate the use of pregnancy-specific reference ranges for thyrotrophin (TSH) and free T4 (FT4) to diagnose thyroid dysfunction during pregnancy. Although many centers use fixed upper limits for TSH of 2.5 or 3.0 mU/L, this may lead to overdiagnosis or even overtreatment. The new guidelines of the American Thyroid Association have considerably changed recommendations regarding thyroid function reference ranges in pregnancy accordingly. Any hospital or physician that is still using the 2.5 or 3.0 mU/l cut-off for TSH during pregnancy should evaluate their own lab-specific cut-offs. The investigator's objective is to establish a rational reference range of serum TSH for the diagnosis of subclinical hypothyroidism in the first, second, and third trimester of pregnant women in the Sancaktepe region in Turkey.

NCT ID: NCT04830293 Completed - Thyroid Clinical Trials

Effect of Head Position During Thyroidectomy on Postoperative Cognitive Functions

Start date: March 1, 2019
Phase:
Study type: Observational [Patient Registry]

The aim of our study is to observe the effect of head-neck position of patients scheduled for thyroidectomy, on carotid artery blood flow, regional cerebral oxygen saturation measured using near-infrared spectroscopy technology, and postoperative cognitive dysfunction.

NCT ID: NCT04763122 Completed - Cancer Clinical Trials

Thyroid Cancer in United Arab Emirates

Start date: September 2008
Phase:
Study type: Observational

The main objective of the study is to assess the trend of clinicopathological features and treatment modalities in patients with thyroid cancer in the largest oncology center in the United Arab Emirates (UAE).

NCT ID: NCT04647006 Completed - Surgery Clinical Trials

Comparison of TOETVA and Conventional Thyroidectomy

TOETVA
Start date: September 23, 2019
Phase: N/A
Study type: Interventional

Introduction-Objective: The application of transoral endoscopic thyroidectomy vestibular approach (TOETVA) is gradually increasing recently. However, it is not clear whether TOETVA is a true minimally invasive thyroidectomy compared to open conventional thyroidectomy. In this study, we aimed to evaluate the TOETVA and open conventional thyroidectomy techniques in terms of postoperative inflammatory response, pain and patient satisfaction. Material and Method: In this prospective study, 40 female patients between the ages of 18-65 were divided into 2 groups of 20 patients: TOETVA: 20 patients, open thyroidectomy: 20 patients. Operation time, inflammatory response with IL-6, white blood cell (WBC) and C-reactive protein (CRP), postoperative pain, postoperative complications and patient satisfaction were evaluated in both groups.

NCT ID: NCT04273711 Completed - Obesity Clinical Trials

Can Thyroidectomy be Considered Safe in Obese Patients?

Start date: December 1, 2019
Phase:
Study type: Observational

Obesity is a growing public health concern in most western countries. More and more patients with high body mass index (BMI) are undergoing surgical procedures of all kinds and, in this context, obese patients are undergoing thyroid surgery more than ever before. This study showed that obesity, in the field of thyroid surgery, is not associated with any increase of postoperative complications. Thus, it is possible to conclude that thyroidectomy can be performed safely in obese patients.