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Thrombolytic Therapy clinical trials

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NCT ID: NCT04870684 Not yet recruiting - Clinical trials for Cerebrovascular Stroke

Thromboelastometry and Ischemic Stroke (ThromboPredict)

Start date: May 1, 2021
Phase:
Study type: Observational

In ischemic stroke, the recanalization rate after intravenous thrombolysis has been estimated to be less than 50% in patients with proximal intracranial artery occlusion; this rate is greater than 80% after endovascular thrombectomy. Thromboelastometry is a method of analysis of coagulation and fibrinolysis in whole blood. The main objective of this study is to evaluate whether the parameters obtained by thromboelastometry are predictive of revascularization at arteriography during mechanical thrombectomy, after treatment with rt-PA thrombolysis.

NCT ID: NCT04309357 Completed - Stroke, Acute Clinical Trials

Thrombolysis Outcome in Ischemic Stroke

TOSSI
Start date: January 1, 2017
Phase:
Study type: Observational

Consecutive patients with diagnosis of acute ischemic stroke and candidate of thrombolytic therapy during Jan 2017-Mar 2019 in BuAli Sina Hospital ,Sari, Iran, enrolled to this cohort study. The demographic data, stroke characteristis, lab data and ... recorded. Then patients evaluate every 3 month until 12 month for fallow up.

NCT ID: NCT03621917 Completed - Stroke, Ischemic Clinical Trials

Evaluation of the Effectiveness of Thrombolytic Therapy in Acute Ischemic Stroke Patients Using NIRS

E-NESE
Start date: November 1, 2017
Phase:
Study type: Observational

Investigators aim to study effectiveness of systemic thrombolytic therapy on acute ischemic stroke patients with near infrared spectroscopy.

NCT ID: NCT03317639 Completed - Acute Stroke Clinical Trials

Improving In-hospital Stroke Service Utilisation in China

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

A cluster randomised controlled trial will be conducted, using hospital as randomisation unit. Hospitals in Zhejiang Province, China, will be randomised into two arms (1:1): an intervention arm and a control arm. Hospitals in the intervention arm will receive a multi-components intervention based on the Behaviour Change Wheel model, whereas hospitals in the control arm will receive no intervention and maintain existing care. The randomisation will be conducted after one-year baseline data collection. The following baseline data will be used for randomisation match: hospital classification, beds in stroke centre, thrombolysis patient number, and percentage of patients receiving thrombolysis within 60 minutes of stroke onset. Hospitals with no stroke centre or with <20 cases received thrombolysis per year will be excluded from the study. The primary outcome will be difference between intervention arm and control arm in the percentage of patients receiving thrombolysis within 60 minutes of stroke onset on the follow-up stage (post-intervention).

NCT ID: NCT02985060 Recruiting - Ischemic Stroke Clinical Trials

Mild Hypothermia After Endovascular Treatment in Acute Ischemic Stroke

HELMET
Start date: November 2016
Phase: Phase 2
Study type: Interventional

To study safety and feasibility of mild therapeutic hypothermia after successful recanalization by mechanical endovascular treatment in patients with acute ischemic stroke and proximal arterial occlusion.

NCT ID: NCT02926742 Recruiting - Pulmonary Embolism Clinical Trials

Submassive Pulmonary Embolism Experience With EKOS

SPEEK
Start date: February 2014
Phase: N/A
Study type: Observational

This single site study evaluates the efficacy of ultrasound accelerated thrombolysis using EKOS Endovascular Device with a standard infusion of thrombolytics for treatment of PE

NCT ID: NCT02131220 Completed - Clinical trials for Myocardial Infarction

Effects of Intracoronary Prourokinase on the Coronary Flow During Primary Percutaneous Coronary Intervention for Acute Myocardial Infarction

ERUPTION
Start date: November 2015
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether intracoronary selective thrombolysis are more effective than tirofiban on the coronary flow during primary percutaneous coronary intervention for the acute myocardial infarction.