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Clinical Trial Summary

The purpose of this study is to investigate the safety and efficacy of endovascular treatment with or without preceding intravenous Tenecteplase in patients with late-window (4.5-24 hours of symptom onset) acute ischemic stroke due to middle cerebral artery (MCA) M1 or M2 occlusion.


Clinical Trial Description

After being informed about the study and potential risks, patients who meet the inclusion criteria will be randomized to endovascular treatment with preceding intravenous rhTNK-tPA (0.25mg/kg, maximum 25mg) or without preceding intravenous rhTNK-tPA in a 1:1 ratio. Written informed consent will be needed. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06221371
Study type Interventional
Source Beijing Tiantan Hospital
Contact Yunyun Xiong, MD
Phone 15710088948
Email xiongyunyun@bjtth.org
Status Recruiting
Phase Phase 3
Start date December 16, 2023
Completion date May 2025