The Effect of Regional Anesthesia Techniques on Brain Tissue Oxygenation in Thoracic Surgery

Thoracic Surgery Clinical Trial

Official title:

The Effect of Regional Anesthesia Techniques on Brain Tissue Oxygenation in Thoracic Surgery Operations Where Single Lung Ventilation is Applied

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04373174
• Other study ID #: BYIERH
• Status: Completed
• Phase: N/A
• Start date: May 1, 2020
• Est. completion date: May 15, 2021

Study information

• Verified date: January 2023
• Source: Bursa Yüksek Ihtisas Education and Research Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Today, it is preferred that the lung with pathology for thorax surgery is not under ventilation during operation in terms of reliability and ease of operation.

For this reason, the anesthesia approach is characteristic and it is ensured that the single lung is not ventilated during the operation by means of specially manufactured intubation tubes. This application can disrupt tissue oxygenation due to both Operation position and single lung ventilation.

Thoracic epidural analgesia, which is applied as the gold standard of Thoracic Surgery, is applied prior to the operation and is provided to assist in postoperative analgesia.

Description:

The aim of this study was to investigate the effect of thoracic epidural analgesia method on brain tissue oxygenation in patients with single lung ventilation.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 60
• Est. completion date: May 15, 2021
• Est. primary completion date: April 1, 2021
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• Patients who were in the American Society of Anesthesiologists (ASA) I-III class

• Underwent Thoracic Surgery

Exclusion Criteria:

• Local anesthetic allergy,

• Bleeding is a diathesis disorder

• Allergic to the drugs used,

• Patients who are not reluctant to participate in the study,

• Presence of infection in the block area,

• Patients whose body mass index is over 30

Related Conditions & MeSH terms

• Aneurysm, Dissecting
• Cerebral Oxygen Saturation
• Epidural Anesthesia
• Thoracic Surgery

Intervention

Device:
• Regional oximetry probe
Regional oximetry probe will be placed in the frontal area of the head

Procedure:
• Thoracic Epidural block
Thoracic epidural block will be applied to the patients before the operation begins

Locations

Country	Name	City	State
Turkey	Bursa Yuksek Ihtisas Training and Research Hospital	Bursa

Sponsors (1)

Lead Sponsor	Collaborator
Bursa Yüksek Ihtisas Education and Research Hospital

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	rso2	Regional oximetry probe will be placed in the frontal area of the head	peroperative 2 hours
Secondary	po2	Arterial blood gas oxygen pressure	peroperative 2 hours
Secondary	ETCO2	End-tidal carbon dioxide (ETCO2) level	peroperative 2 hours