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Thoracic Surgery clinical trials

View clinical trials related to Thoracic Surgery.

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NCT ID: NCT06310785 Not yet recruiting - General Anesthesia Clinical Trials

Esketamine Anesthesia in Thoracic Surgery

Start date: April 1, 2024
Phase: N/A
Study type: Interventional

Esketamine group was induced with esketamine 0.5 mg/kg, propofol 2 mg/kg, and rocuronium bromide 0.9 mg/kg. Anesthesia is maintained with propofol 5 mg/kg/h and esketamine 0.5 mg/kg/h. Anesthesia induction in the opioid group Sufentanil 0.5 ug/kg, propofol 2 mg/kg, rocuronium bromide 0.9 mg/kg. Anesthesia is maintained with propofol 5 mg/kg/h and remifentanil 1 ug/kg/h.

NCT ID: NCT06261411 Enrolling by invitation - Thoracic Surgery Clinical Trials

Lung Ultrasound as Alternative to Radiation in Thoracic Surgery

LUS-ART
Start date: February 12, 2024
Phase: N/A
Study type: Interventional

This projects aim is to study the effects of substitute conventional chest x-ray with lung ultrasound for patients undergoing thoracic surgery. Participants in the study will be randomized to either ultrasound or routine chest x-ray as the primary method of diagnosis after having received surgery to their lungs.

NCT ID: NCT06246617 Recruiting - Thoracic Surgery Clinical Trials

Valuate the Clinical Performance and Safety of da Vinci SP Surgical System

Start date: October 25, 2023
Phase: N/A
Study type: Interventional

This clinical trial is a real-world study to evaluate the clinical performance and safety of da Vinci SP Surgical System ("SP single-port robot" for short) for single-port robot-assisted thoracic surgeries in the real world, providing a real world evidence for clinical application of the product in the Chinese population.

NCT ID: NCT06159517 Recruiting - Cardiac Surgery Clinical Trials

Heart Lung Machine Registry

HeaLMe
Start date: December 21, 2023
Phase:
Study type: Observational

The HeaLMe post-market clinical follow-up registry is undertaken to evaluate the safety and performance of the index devices Heart Lung Machine HL 40 and Temperature Probes TPO-D-HLM L1.8 Adult / Pediatric in patients undergoing cardiac / thoracic / vascular surgery.

NCT ID: NCT05968456 Recruiting - Anesthesia Clinical Trials

Complexity and Frailty in Cardiothoracic and Vascular Anesthesia (CAfCA). Prospective Multicentric Observational Study

CAfCA
Start date: October 10, 2023
Phase:
Study type: Observational

Frailty is a multidimensional syndrome characterized by a decline in physiological homeostatic reserve, which translates into an increased susceptibility to adverse events and unfavorable outcomes following even small exposures to physical, physiological or psychosocial stress. In the European population up to 69 years, the prevalence is generally 6,5%, beyond 85 years of age it exceeds 50% and reaches 65% in the over-ninety population. The prevalence of frailty in the surgical population varies, depending on the studies, from 10 to 40%. Frailty and its severity grade represent themselves noticeably as strong predictors of adverse postoperative outcomes. The strongest evidence of association is recorded between frailty and mortality at 30 days. The purpose of this study is to describe the characteristics of patients undergoing anesthesia for cardiothoracic and vascular surgery, with a specific focus on frailty elements and associated comorbidities that necessitate surgery. This data analysis will provide valuable insights into the interaction between frailty, multimorbidity, and the perioperative pathway of patients undergoing cardiothoracic and vascular anesthesia.

NCT ID: NCT05946707 Completed - Clinical trials for Mechanical Ventilation

Effects of Oxygen Supply After Lung Isolation in Thoracic Surgery

Start date: July 19, 2023
Phase: N/A
Study type: Interventional

The goal of this randomized clinical trial is to compare a liberal versus restrictive oxygen supply (fraction of inspired oxygen, FiO2) strategy in patients scheduled for thoracic surgery requiring one-lung ventilation during lung isolation. The primary and secondary outcome parameters are: - oxygenation of the blood after 30 minutes of one-lung ventilation, assessed by PaO2/FiO2 ratio - time to lung collapse after start of one-lung ventilation Participants in the control goup will receive an oxygen content of 100% before lung isolation, which will be subsequently decreased to achieve normoxia or mild hyperoxia (PaO2 of 75-120 mmHg). The intervention group will receive the previous, during two-lung ventilation set, oxygen content and after lung isolation oxygen supply will be increased to secure adequate oxygenation of the blood (PaO2 75-120 mmHg) during one-lung ventilation. The investigators hypothesize, that a higher fraction of inspired oxygen may impede hypoxic pulmonary vasoconstriction of the collapsed lung and thus decrease overall oxygenation performance during one-lung ventilation. Secondary endpoint will be the time to lung collapse, as a lower fraction of inspired oxygen and thus a higher nitrogen content may impede lung collapse.

NCT ID: NCT05910788 Recruiting - Thoracic Surgery Clinical Trials

High-Flow Nasal Catheter (HFNC) Compared With Conventional Oxygenation

Start date: July 28, 2023
Phase: N/A
Study type: Interventional

The purpose of this study, is to clarify whether there is benefit from the perioperative use of HFNC in thoracic surgeries, from intubation to the postoperative period, evaluating hipoxemia during orotracheal intubation, immediate complications after intubation, mortality and in-hospital complications.

NCT ID: NCT05901389 Not yet recruiting - Pain, Postoperative Clinical Trials

Continuous Lidocaine Infusion Via Closed Chest Drainage Tube for Pain Control After Thoracoscopic Partial Lung Resection

Start date: June 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to learn about the effects on postoperative analgesia of continuous lidocaine infusion via closed chest drainage tube for patients undergoing thoracoscopic partial lung resection. The main questions it aims to answer are: - To explore whether continuous lidocaine pumping via closed chest drainage tube has good analgesic and anti-inflammatory effects for patients undergoing partial thoracoscopic pneumonectomy. - Whether the multimodal analgesia combined with continuous lidocaine pump can reduce the postoperative application of opioids, reduce the occurrence of postoperative complications, and promote the recovery of postoperative lung function and accelerate recovery. For participants who undergoing the thoracoscopic partial lung resection with postoperative indwelling drainage tube, the epidural tube fixed in the drainage tube is connected to the completed infusion pump (marking the chest drain for analgesia). The comparison group only accept the intravenous analgesia after surgery.

NCT ID: NCT05896150 Recruiting - Thoracic Surgery Clinical Trials

Intercostal Cryoanalgesia for Acute Pain After VATS Lung Resection

CRYO-VATS
Start date: November 9, 2023
Phase: N/A
Study type: Interventional

Intercostal cryoanalgesia is a technique that allows extensive and prolonged analgesia of the hemithorax. The aim of this study is to demonstrate the efficacy of intercostal cryoanalgesia as an adjunct to a single-injection paravertebral block for the management of acute thoracic pain after VATS lung resection surgery.

NCT ID: NCT05827328 Completed - Thoracic Surgery Clinical Trials

Explore the Optimal Surgical Timing for Lung Surgery and Mediastinal Surgery After COVID-19 Infection

Start date: January 29, 2023
Phase:
Study type: Observational

Exploring the optimal interval time in patients with the clinical diagnosis of lung cancer or mediastinal tumors indicated for thoracic surgeries after SARS-CoV-2 infection by comparing 30-day mortality and 30-day morbidity.