Preoperative Inspiratory Muscle Training Effects on the Perioperative Inflammatory Reaction in Cardiac Surgery.

Thoracic Surgery Clinical Trial

— EMI HiPo  

Official title:

High Intensity Preoperative Inspiratory Muscle Training (IMTHi) Effects on the Perioperative Inflammatory Reaction in Cardiac Surgery With an Associated Biocollection.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03158402
• Other study ID #: 2017-A00216-47
• Status: Completed
• Phase: N/A
• Start date: February 14, 2018
• Est. completion date: January 8, 2021

Study information

• Verified date: January 2023
• Source: University Hospital, Angers
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This study evaluates the impact of preoperative high-intensity inspiratory muscle training (IMThi) before cardiac surgery on perioperative inflammatory response. Half participants will receive high intensity inspiratory muscle training and the others a sham inspiratory muscle therapy.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 30
• Est. completion date: January 8, 2021
• Est. primary completion date: June 12, 2019
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Waiting for thoracic surgery with valve replacement
• Preoperative surgeon consultation between 3 and 6 weeks before surgery

Exclusion Criteria:

• Patient with antecedent of lung surgery
• Patient with neuromuscular or neurovascular disease
• Non anticipated surgery with a time between surgeon consultation and surgery inferior to 3 weeks.
• Inhability to do the preoperative exercises

Related Conditions & MeSH terms

• Inflammation
• Prehabilitation
• Respiratory Aspiration
• Respiratory Therapy
• Thoracic Surgery

Intervention

Other:
• Prehabilitation with inspiratory muscle training
3 to 6 weeks of two times a day inspiratory muscle training at 80% of the Maximum Inspiratory Pressure.

Locations

Country	Name	City	State
France	University Hospital Angers	Angers

Sponsors (1)

Lead Sponsor	Collaborator
University Hospital, Angers

Country where clinical trial is conducted

France, 

References & Publications (1)

Furon Y, Dang Van S, Blanchard S, Saulnier P, Baufreton C. Effects of high-intensity inspiratory muscle training on systemic inflammatory response in cardiac surgery - A randomized clinical trial. Physiother Theory Pract. 2023 Jan 13:1-11. doi: 10.1080/09 — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Preoperative STNFr1 level	Post training and preoperative Serum concentration of the SRNFr1 cytokine.	Outcome is evaluated at the training initiation and re evaluated 24hours before the surgery