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Tennis Elbow clinical trials

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NCT ID: NCT05021354 Active, not recruiting - Clinical trials for Humeral Epicondylitis, Lateral

Effectiveness Of A Physiotherapy Treatment Plan In Lateral Epicondylalgia

Start date: August 1, 2023
Phase: N/A
Study type: Interventional

Purpose: Test the effectiveness of a physiotherapy treatment in 90 patients with Lateral epicondylalgia (LE).

NCT ID: NCT04686799 Active, not recruiting - Clinical trials for Lateral Epicondylitis

Doxycycline for Elbow Tendinopathy

Start date: December 3, 2020
Phase: Phase 1
Study type: Interventional

To evaluate the feasibility of subantimicrobial -dose (SD) doxycycline to improve outcomes of nonsurgical management of elbow tendinopathy via matrix metalloproteinase (MMP) inhibition as well as evaluate if participants will be compliant to with prescribed medication and exercise treatment. Our working hypothesis is that patients with elbow tendinopathy will be receptive to treatment with SD-doxycycline and compliant with the prescribed treatment.

NCT ID: NCT04556825 Active, not recruiting - Clinical trials for Lateral Epicondylitis

Arthroscopic Treatment Combined With PRP Injection for Refractory Elbow Epicondylitis

Start date: October 1, 2020
Phase: N/A
Study type: Interventional

This study is a prospective randomized controlled study of different arthroscopic treatments for refractory external humeral epicondylitis combined with platelet rich plasma (PRP) injection. The patients with intractable external humeral epicondylitis were randomly divided into groups before the operation. After the arthroscopic operation was completed, they were divided into a local PRP injection group and a control group (normal saline) to perform additional operations on the damaged tendons, each for up to half a year after the operation. In different time periods, the quantitative and qualitative indicators including pain, functional score, muscle strength, MRI performance, etc. were compared between groups at the same time period to evaluate the difference in the effect of arthroscopic treatment combined with PRP on the treatment of damaged tendons. Determine the effectiveness of PRP. At the same time, in the process of arthroscopic treatment, look for risk factors that affect the curative effect of intractable external humeral epicondylitis, as well as the causes and prevention of common complications.

NCT ID: NCT03978897 Active, not recruiting - Clinical trials for Lateral Epicondylitis

Trial of Blood Flow Restriction Plus Physical Therapy vs. Physical Therapy Alone for Lateral Epicondylitis

Start date: July 1, 2019
Phase: N/A
Study type: Interventional

Open label randomized controlled trial comparing evidenced based physical/occupational therapy vs. physical/occupational therapy including blood flow restriction tourniquet in the treatment of lateral epicondylitis (tennis elbow).

NCT ID: NCT03656185 Active, not recruiting - Clinical trials for Osteochondritis Dissecans

Elbow Arthroscopy Data Analysis

EA
Start date: March 15, 2018
Phase:
Study type: Observational

The purpose of this study is to evaluate preoperative objective measurements and operative objective measurements to determine if there is any effect to postoperative outcomes. Patients who were 13 years old or greater at the time of arthroscopic osteocapsular release were followed clinically and radiographically to determine best practice and optimal treatment and technique, risk and rate of complication, and postoperative outcomes.

NCT ID: NCT03504111 Active, not recruiting - Clinical trials for Lateral Epicondylitis

PRINT Trial (Platelet Rich Injection vs Needle Tenotomy)

PRINT
Start date: July 2016
Phase: N/A
Study type: Interventional

Chronic tendinopathy is often very difficult to treat and causes many patients who suffer from it to have significant pain and loss of function leading to disability. Ultrasound has been shown to be very effective in aiding in the diagnosis of soft tissue disorders including tendinopathy and can help to rule in or out other potential causes that may be confounders. Numerous methods have been tried to treat tendinopathy including rest, NSAIDs, bracing, physical therapy, extracorporal shock wave therapy, anesthetic injections, steroid injections, prolotherapy, nitro patches, surgery and more recently platelet rich plasma, all of which have had conflicting results in the literature. Platelet rich plasma (PRP) is an autologous blood product that contains a high concentration of platelet-derived growth factors that have the potential to enhance healing. In a study by Mishra et al, common extensor tenindosis showed improved pain symptoms (71% vs 55% at 24 weeks) with tenontomy combined with PRP compared to percutaneous needle tenontomy alone. Current studies show conflicting results as to whether PRP improves chronic tendinopathy when compared to steroid injections, and many do not have any control group or comparison group. Percutaneous needle tenotomy is the use of a large gauge needle (18 gauge), which may be performed under ultrasound guidance, to fenestrate repeatedly the area of tendinopathy within a tendon in order to disrupt tendinopathic tissue and to induce bleeding and clot formation with release of growth factors. To date there are no published studies comparing percutaneous needle tenotomy (PNT) alone vs. PRP without concomitant tenotomy. Current literature suggests that needle tenotomy may be superior but no head to head studies are currently found in the literature. Most of the published literature of non-operative treatment of tendinosis does not yield clearly designed trials with clear selection criteria. Current literature also lacks studies with significant number of patients that meet both clinical and ultrasound criteria thus previous studies lack sufficient power. The PRINT TRIAL: may enhance the understanding of a superior treatment if it exists. Hypothesis: In active adults with chronic tendinopathy who have failed to respond to standard of care treatment, the use of ultrasound guided percutaneous needle tenotomy (PNT) alone is superior to PRP without concomitant tenotomy.

NCT ID: NCT03449082 Active, not recruiting - Clinical trials for Lateral Epicondylitis

Treatment of Intractable Common Extensor Tendon Injury Using Mesenchymal Stem Cells (Allo-ASC)

Start date: May 4, 2018
Phase: Phase 2
Study type: Interventional

The aim of this study is to evaluate the efficacy and safety of intra-tendon injection of allogeneic adipose-derived mesenchymal stem cells (Allo-ASC) in intractable common extensor tendinosis patients in comparison with a control treatment.

NCT ID: NCT02425982 Active, not recruiting - Tennis Elbow Clinical Trials

Finnish Tennis Elbow Trial Pilot Study

FINITE
Start date: August 2015
Phase:
Study type: Observational

The study aims to investigate the natural course and the results of operative treatment of chronic tennis elbow (TE). Chronic is defined as symptoms having lasted for more than a year. The investigators will also study the effect of pain catastrophising on the subjective outcome, the patient acceptable symptomatic state and the response shift phenomenon in TE. The study will also ascertain the feasibility of a multi-center randomised, controlled trial (RCT), and test and refine the co-operation and interaction of the planned RCT centers.

NCT ID: NCT02308514 Active, not recruiting - Clinical trials for Lateral Epicondylitis

Does Adding Cryostimulation to Conservative Care Help in Managing Chronic Lateral Epicondylitis? a Pilote Study

Start date: September 2014
Phase: N/A
Study type: Interventional

In this study the investigators want to measure the impact or effects of adding cryostimulation to the conservative care of chronic lateral epicondylitis. The rapid fall in skin temperature above the injured tissues is presume to have a positive effect in the healing process. The combination of conservative care and cryostimulation could then be appreciated. The investigators chose to measure these effects with 3 elements: visual analog pain scale, validated elbow questionnaire and pain free grip strength. This pilot study consist in a two arm design, each arm including 15 patients.

NCT ID: NCT01789632 Active, not recruiting - Tennis Elbow Clinical Trials

Impact of Platelet Rich Plasma Over Alternative Therapies in Patients With Lateral Epicondylitis

IMPROVE
Start date: January 2013
Phase: Phase 2
Study type: Interventional

This Pilot study is a Multicenter, Randomized Trial comparing autologous platelet rich plasma (PRP) versus autologous whole blood versus dry needle tendon fenestration on pain and quality of life in patients with lateral epicondylitis (tennis elbow). We want to find out if pain and mobility are improved in people who receive an injection of PRP compared to a group of people who receive an injection of whole blood, a group treated with dry needle tendon fenestration and a group of people who receive no injection.