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Surgical Site Infection clinical trials

View clinical trials related to Surgical Site Infection.

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NCT ID: NCT04258098 Completed - Colorectal Cancer Clinical Trials

Prophylatic Effect Preoperative Antibiotics With Mechanical Bowel Preparation in SSIs: A Propensity Analysis

Start date: January 1, 2011
Phase:
Study type: Observational

Surgical site infections (SSIs) are a major postoperative complication after colorectal surgery. Current study aims to evaluate prophylactic function of oral antibiotic intake (OA) in combination with mechanical bowel preparation (MBP) relative to MBP alone with respect to postoperative SSIs incidence. A retrospective analysis of eligible patients was to conducted using the databases of the Gastrointestinal Surgery Centre, Third Affiliated Hospital of Sun Yat-sen University from 2011 to 2017. Data pertaining to postoperative hospital stay length, expenses, SSIs incidence, anastomotic fistula incidence, and rates of other complications wloud be extracted and compared. A propensity analysis was conducted to minimize bias associated with demographic characteristics.

NCT ID: NCT04255927 Completed - Clinical trials for Surgical Site Infection

Triclosan-antibacterial Sutures Impact on the Incidence of Surgical Site Infection in Laparoscopic Surgeries.

Start date: February 5, 2020
Phase: Phase 4
Study type: Interventional

Comparing the incidence of PSI in cases using coated Polyglactin 910 suture with Triclosan and cases using Polyglactin 910 suture without Triclosan in laparoscopic sleeve gastrectomy, laparoscopic appendectomy or laparoscopic cholecystectomy.

NCT ID: NCT04233424 Completed - Clinical trials for Surgical Site Infection

D-PLEX 311: Safety and Efficacy of D-PLEX in the Prevention of Post Abdominal Surgery Incisional Infection

Start date: June 24, 2020
Phase: Phase 3
Study type: Interventional

Phase III, Prospective, Multinational, Multicenter, Randomized, Controlled, Two-arm, Double Blind Study to assess Efficacy and Safety of D-PLEX Administered Concomitantly with the Standard of Care (SoC), compared to a SoC treated control arm, in prevention of post abdominal surgery incisional infection.

NCT ID: NCT04218110 Completed - Clinical trials for Surgical Site Infection

Preoperative Skin Preparation Study to Evaluate the Antimicrobial Capabilities of Four Test Substances

Start date: February 11, 2020
Phase: Phase 3
Study type: Interventional

Comparative study of antimicrobial effectiveness evaluation of of 26ml Project X, 10.5ml Project X, 5.1ml Project X and Prevantics Maxi swabstick following ASTM E1173 - Standard test method for evaluation of preoperative, precatheterization or preinjection skin preparations.

NCT ID: NCT04146116 Completed - Clinical trials for Surgical Site Infection

Nasal Decolonization for Orthopedic Trauma Patients

Start date: February 19, 2020
Phase: Phase 4
Study type: Interventional

Many surgical site infections are caused by bacteria that is transferred from a patient's nose to their open surgical wound. Some small studies have shown that putting povidone-iodine in a patient's nose reduces this risk. This study aims to evaluate the real-world effectiveness of nasal povidone-iodine (PROFEND®) in a group of 50 patients at the University of Iowa.

NCT ID: NCT04067843 Completed - Clinical trials for Surgical Site Infection

Effect of Photodynamic Treatment on Skin Microbiome. Single Center Study

PHOMIC
Start date: September 26, 2019
Phase: N/A
Study type: Interventional

The overarching aim of this research project is to prevent orthopedic implant-associated infections. This study aims to investigate if photodynamic therapy has an effect on bacterial skin colonization and decrease number of colonizing bacteria associated with sebaceous and sweat glands in order to improve skin antisepsis strategies for the prevention of surgical site infections.

NCT ID: NCT04057092 Completed - Clinical trials for Surgical Site Infection

Perioperative Immunonutrition in Patients Undergoing Gynecologic or General Elective Surgery (PURPOSE)

PURPOSE
Start date: August 1, 2018
Phase: N/A
Study type: Interventional

The objective of the implementation pilot is to assess the practicality of introducing a perioperative immunonutrition protocol into a hospital environment as well as a true measure of impact on the rate of surgical site infection (SSI).

NCT ID: NCT04055233 Completed - Clinical trials for Surgical Site Infection

Reduction of Postoperative Wound Infections by Antiseptica?

RECIPE
Start date: February 1, 2015
Phase: Phase 3
Study type: Interventional

Wound infections are a frequent complication in abdominal surgery. The investigators hypothesize that the antiseptic solution 0.04 % polyhexanide (serasept) may reduce occurrence of postoperative wound infections compared to NaCL (saline) solution in a prospective randomized setting.

NCT ID: NCT04048356 Completed - Clinical trials for Urinary Incontinence

Chlorhexidine vs. Iodine for Vaginal Preparation in Urogynecologic Procedures

CLNUP
Start date: July 15, 2019
Phase: Phase 3
Study type: Interventional

This is a randomized controlled trial to determine if there is a difference between chlorhexidine gluconate and povidone iodine vaginal preparations for urogynecological surgery post operative infections.

NCT ID: NCT03962907 Completed - Clinical trials for Surgical Site Infection

Preoperative Decolonization and Surgical Site Infections in Orthopaedic Surgery - 2 Year Outcome in Prosthetic Surgery

DECO-SSI
Start date: January 1, 2019
Phase: Phase 4
Study type: Interventional

Surgical site infections in orthopaedic surgery are a major problem. Decolonization has been suggested to reduce infection rates. The study was designed as a prospective, controlled, randomized, single-blinded trial to assess the influence of a decolonization procedure in S. aureus and non - S. aureus carriers. In this trial the 2 - year outcome in the subpopulation of prosthetic elective orthopaedic surgery will be evaluated.