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Surgical Site Infection clinical trials

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NCT ID: NCT06368102 Not yet recruiting - Clinical trials for Surgical Site Infection

Prophylactic Effects for Preventing Surgical Site Infection in Third Molar Surgery

Start date: May 1, 2024
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine the incidence of surgical site infection (SSIs) after third molar surgery for different duration of intravenous ampicillin administration.

NCT ID: NCT06363877 Not yet recruiting - Clinical trials for Surgical Site Infection

Diluted Aqueous Povidone-Iodine Compared to Saline to Decrease Surgical Site Infections

Start date: May 2024
Phase: Phase 3
Study type: Interventional

This is a multicenter randomized controlled trial of 1100 patients to evaluate the superiority of combined intraoperative wound irrigation with intraoperative peritoneal lavage with dilute aqueous povidone-iodine compared to normal saline in male and female patients between the ages of 18 and 80 years old undergoing emergency laparotomies with Centers for Disease Control (CDC) class 2 and 3 wounds.

NCT ID: NCT06338163 Not yet recruiting - Clinical trials for Surgical Site Infection

Polihexanide SSIs Measures Bundle (PSMB) During Enhanced Recovery After Major Digestive Surgery

POSSIBLE
Start date: July 1, 2024
Phase: Phase 4
Study type: Interventional

This is a randomized controlled, prospective, multicenter superiority trial with two parallel treatment groups and single blinding (local investigators performing postoperative follow up will be blinded for group allocation), with prospective enrollment planned from July 2024 to June 2025 in 20 Italian surgical centers. All patients undergoing elective major gastro-intestinal (GI) tract surgery (upper GI, HPB, & lower GI) will be included in a prospective database after written informed consent. A total of 2,000 patients is expected based on a mean of 100 cases per center.

NCT ID: NCT06201377 Not yet recruiting - Clinical trials for Surgical Site Infection

Analysis of Early Healing of Sutures in Periodontal Surgery

Sutures
Start date: January 8, 2024
Phase: N/A
Study type: Interventional

The main objective is to analyze post-surgical periodontal healing after conventional periodontal surgery where an absorbable suture coated with clorhexidine (Novosyn Clorhexidine) versus conventional sutures without chlorhexidine (Novosyn) will be used a pilot randomized clinical study has been designed. Up to authors´ knowledge until now there are no studies to evaluate periodontal healing after periodontal surgery in combination with this kind of sutures.

NCT ID: NCT06164444 Not yet recruiting - Clinical trials for Surgical Site Infection

Cluster Randomised Trial Testing Disposable Versus Reusable drApes and Gowns for Green OperatiNg Theatres

DRAGON
Start date: March 1, 2024
Phase: N/A
Study type: Interventional

Multicentre non-inferiority cluster randomised trial testing Disposable versus Reusable drApes and Gowns for green OperatiNg theatres. A pragmatic 1:1 international multi-centre non-inferiority cluster randomised controlled trial, with an internal pilot. Clusters are individual hospitals.

NCT ID: NCT06157645 Not yet recruiting - Postoperative Pain Clinical Trials

Prophylactic Mesh Reinforcement for Stoma Closure

Start date: August 1, 2024
Phase: N/A
Study type: Interventional

n the current work we are aiming to compare between the mesh-reinforced stoma closure and the anatomical closure in terms of the risk of developing surgical site incisional hernia (SSIH),incidence of surgical site infection , post-operative Pain and Hospital stay

NCT ID: NCT06108791 Not yet recruiting - Clinical trials for Surgical Site Infection

Intraoperative Oxygen Concentration on Incidence of Surgical Site Infection

Start date: January 2024
Phase: N/A
Study type: Interventional

Surgical site infections (SSI) are the most common healthcare-associated infections and sources of morbidity and over-mortality. Factors that have been proven to reduce SSI include antimicrobial prophylaxis, maintenance of perioperative normothermia, avoidance of hyperglycemia, proper surgical techniques, and adequate pain relief postoperatively

NCT ID: NCT06063629 Not yet recruiting - Clinical trials for Surgical Site Infection

Roles of Prophylactic Subcutaneous Drain in Preventing Surgical Site Infection in Surgical Wound After Abdominal Surgery

Start date: June 1, 2024
Phase: N/A
Study type: Interventional

Surgical site infections (SSI) pose a common challenge in the field of surgery. Current evidence and literature do not provide clear consensus whether the use of subcutaneous drainage will help reduce the incidence of SSI in patients who underwent abdominal surgery, especially in wounds that are categorized as contaminated (class 3) or dirty/infected (class 4). The objective of this clinical study is to compare the rate of surgical site infection in contaminated and dirty/infected surgical wounds among patients whose wounds are inserted with subcutaneous drainage and patients who are not inserted with subcutaneous drainage.

NCT ID: NCT05641792 Not yet recruiting - Hyperglycemia Clinical Trials

Continuous Glucose Monitoring for Emergency Laparotomy

CLUE
Start date: March 15, 2023
Phase: N/A
Study type: Interventional

CLUE trial aims to determine the feasibility and predictive value for surgical site infection (SSI) of continuous glucose monitoring (CGM) in emergency laparotomy patients with diffuse peritonitis.

NCT ID: NCT05392400 Not yet recruiting - Clinical trials for Surgical Site Infection

The Use of Steri3X for Prevention of Post-operative Wound Infections in Cesarean Sections

Start date: February 7, 2023
Phase: Phase 2
Study type: Interventional

Postpartum infection if a major cause of maternal morbidity and mortality and surgical site infections are some of the common complications following cesarean section. This study aims to determine the effect of Steri3X on the incidence of cesarean section SSI at Regional One Hospital.