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Surgical Site Infection clinical trials

View clinical trials related to Surgical Site Infection.

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NCT ID: NCT04631185 Completed - Clinical trials for Surgical Site Infection

Surgical Site Infection and Antibiotic Use Study

ASSERT
Start date: May 7, 2021
Phase: N/A
Study type: Interventional

This study is a prospective, multi-institutional, noninferiority, randomized control trial that will compare the efficacy of two antibiotic treatments in preventing SSI in patients receiving immediate breast reconstruction with tissue expanders (TE-BR). The patients will be randomly assigned to one of the two treatment groups. One group will receive a single dose of antibiotics just before surgery and if necessary, more doses during the surgery. The other group will receive the same treatment as the first group, along with an additional week of antibiotics after surgery. The study will assess the rates of SSI from the two groups. It will also assess the type, duration and method (oral vs. intravenous) of subsequent antibiotic use for patients who develop SSIs in each group.

NCT ID: NCT04618276 Completed - Clinical trials for Surgical Site Infection

Effect of Photodynamic Therapy on Skin Microbiome. Single Center Study (PHOMIC-II)

Start date: January 15, 2021
Phase: N/A
Study type: Interventional

The overarching aim of this research project is to prevent orthopedic implant-associated infections. This study aims to investigate if PDT has an effect on bacterial skin colonization in order to improve skin antisepsis strategies for the prevention of surgical site infections.

NCT ID: NCT04592328 Completed - Clinical trials for Surgical Site Infection

Sternal Wound and Aortic Graft (SWAG), an Observational Cohort Study.

SWAG
Start date: October 12, 2020
Phase:
Study type: Observational

The aim of this study is to systematically explore the perioperative presence of P acnes in all layers of sternal wound incision as well as contamination of graft material and prosthetic valves during primary operation. Secondly, to compare if different regimes of antibiotics affects the bacterial growth. Cultures will be taken from the skin, subcutaneous, and from the implanted valve prostheses with a rayon swab.Graft and Felt material will, after being pressed subcutaneous for 15 sec, placed into prepared sterile bottles containing broth for aerobe and anaerobe cultures. Surgical gloves will be cultured.

NCT ID: NCT04579705 Completed - Clinical trials for Surgical Site Infection

Surgical Hand Scrubbing Methods and the Duration of Scrubbing Time

Start date: November 5, 2019
Phase: N/A
Study type: Interventional

Surgical hand scrubbing is the removal of transient flora and reduction of permanent flora as much as possible before any sterile gloves are worn before any surgical intervention. It is a cheap and easy method to prevent infections. Effective use of surgical hand scrubbing has an important role in preventing and reducing the transfer of health-related infections. Although many studies have been performed on surgical hand scrubbing, no standard practice has been found in the method of scrubbing and optimal duration of scrubbing time. The aim of this study is to compare evidence-based surgical hand scrubbing methods in order to prevent surgical site infections. Methods H0: There is no difference between the effectiveness of different surgical hand scrubbing methods on the bacterial flora in the hand H1: There is a difference between the effectiveness of different surgical hand scrubbing methods on the bacterial flora in the hand. Time H0: There is no difference between the effectiveness of different the duration of scrubbing time on the bacterial flora in the hand. H1: There is a difference between the effectiveness of different the duration of scrubbing time on the bacterial flora in the hand.

NCT ID: NCT04446923 Completed - Clinical trials for Surgical Site Infection

Surgical Hand Antisepsis With Propan-ol-1 60% Per Rubbing and Scrubbing

Start date: June 28, 2020
Phase: Phase 4
Study type: Interventional

The present study evaluates the effects of to compare bactericidal efficacy using the reference antiseptic product propan-ol-1 60% using the hand rub method versus hand scrub method in order to test if pass the standard european norm 12791.

NCT ID: NCT04350203 Completed - Clinical trials for Surgical Site Infection

Surgical-Site Infection After Laparoscopic Right Colectomy

Start date: January 1, 2011
Phase:
Study type: Observational

Laparoscopic right colectomy with intracorporeal anastomosis seems to be associated with several short-term benefits. It could reduce the postoperative infection rate and shorten the hospital stay. This study aimed to evaluate the postoperative surgical site infection (SSI) rate after laparoscopic right hemicolectomy with intracorporeal anastomosis, compared to extracorporeal anastomoses.

NCT ID: NCT04345809 Completed - Clinical trials for Surgical Site Infection

Effect of Prophylactic Prosthesis Placement With Versus Without Omega-3 at the Umbilical Trocar Level on Surgical Site Infection and Herniation After Laparoscopic Cholecystectomy in Patients With Risk Factors.

Start date: January 2016
Phase:
Study type: Observational

TITLE: Effect of prophylactic prosthesis placement with versus without omega-3 at the umbilical trocar level on surgical site infection and herniation after laparoscopic cholecystectomy in patients with risk factors. OBJECTIVE: To evaluate whether the placement of a synthetic prosthesis with omega-3 in its composition at the level of the umbilical trocar after laparoscopic cholecystectomy versus the placement of a synthetic umbilical prosthesis without omega-3 in its composition decreases the rate of surgical site infection (SSI) and trocar site hernia (TSH) in patients with risk factors for infection and herniation.

NCT ID: NCT04341805 Completed - Clinical trials for Surgical Site Infection

Application of Hyperoxygenated Fatty Acids in a Surgical Wound After Laparoscopic Cholecystectomy.

Start date: January 6, 2018
Phase: N/A
Study type: Interventional

TITLE: Application of hyperoxygenated fatty acids (PrevOmega) in a surgical wound of the umbilical trocar after laparoscopic cholecystectomy with placement of prostheses in patients with risk factors. OBJECTIVE: This study aimed to evaluate the effect of topical application of hyperoxygenated fatty acids (AGHO), PrevOmega, at the umbilical trocar level after laparoscopic cholecystectomy with prosthesis placement, regarding its non-application, on the infection rate. of the surgical site (ISQ) and eventration of the trocar orifice (EOT), in patients with risk factors for ISQ AND EOT. METHODS: A prospective, double-blind, randomized study was performed in patients operated on for scheduled cholelithiasis, who also had any of the following risk factors that increase the appearance of SSI or OOT: BMI> 30kg / m2, Diabetes Mellitus, age> 65 years and Chronic Obstructive Pulmonary Disease. Group A was administered physiological saline (SSF) at the umbilical trocar level at the end of the intervention versus the administration of PrevOmega to group B. The study was carried out between January 2018 and January 2020 and is registered in the European Database of Clinical Trials with the EudraCT Code: 2018-002260-67.

NCT ID: NCT04310878 Completed - Clinical trials for Surgical Site Infection

Gaps Between Evidence and Practice in Prevention of Surgical Site Infection in Spain

SurveyOIC
Start date: April 1, 2019
Phase:
Study type: Observational

Web-based survey to members of 10 Spanish Associations of surgical nurses and surgeons of different specialities to know the application of preventative measures for surgical site infection.

NCT ID: NCT04303390 Completed - Clinical trials for Surgical Site Infection

24 Vs 48 Hours of Cefazolin or Cefuroxime as Prophylaxis

Start date: February 6, 2018
Phase: Phase 4
Study type: Interventional

A randomized control trial studying the effect of prophylactic antibiotics to reduce surgical site infections following cardiac surgery in adults using 1st generation cephalosporin (Cefazolin) or 2nd generation cephalosporin (Cefuroxime).