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Surgery clinical trials

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NCT ID: NCT05444036 Completed - Surgery Clinical Trials

Caudal Ketamine-bupivacaine More Effective Than Bupivacaine-saline

Start date: September 1, 2018
Phase: Phase 1
Study type: Interventional

Because pain is difficult to measure in children, post-operative pain is frequently undertreated in this age range. Pain treatment is required in children due to the high emotional component of pain. Pain is a multidimensional, subjective, perceptual event having a variety of qualities such as intensity, quality, time course, and effects that are perceived differently by each person. Because the operational definition of pain necessitates self-report, pain experienced by children and babies is frequently overlooked, if not ignored. When general anesthesia is paired with regional procedures, children of all ages are exposed to less intravenous and inhalational anesthetics and analgesics, leaving them nearly free of nausea, vomiting, itching, or unneeded drowsiness. Being completely awake and able to drink soon after surgery, as well as having no issues breathing even after lengthy surgery, are significant benefits that children and parents value.

NCT ID: NCT05440305 Completed - Surgery Clinical Trials

Unicentric Form of Castleman Disease - Surgery Therapy Benefit

Start date: January 1, 2011
Phase:
Study type: Observational

Observation study on patients with unicentric form of Castleman disease, evaluation of surgical treatment benefit. Observation of surgical treatment strategy.

NCT ID: NCT05436392 Completed - Surgery Clinical Trials

De-adopting Routine Preoperative Benzodiazepines for Older Surgical Patients

DROP-Benzo
Start date: August 8, 2022
Phase: N/A
Study type: Interventional

Over 21 million surgical procedures take place among adults aged 65 and older in the US each year, and most older surgical patients in the US now receive benzodiazepines (e.g., midazolam, lorazepam) during anesthesia care. This occurs despite recommendations to avoid these medications in older patients due to associated medical risks and lack of demonstrated benefit. In other words, routine benzodiazepine administration to older surgical patients is likely to represent low-value care that is a suitable target for de-adoption. In this study, we will evaluate a United States Anesthesia Partners (USAP, Dallas, TX) quality improvement initiative using peer comparison feedback to clinicians and/or mailed informational letters to patients as strategies to encourage physician de-adoption of routine preoperative benzodiazepine administration to older surgical patients. In partnership with USAP, this study will be conducted using randomization to evaluate its effect.

NCT ID: NCT05428098 Completed - Prostate Cancer Clinical Trials

The Effect of the Educatıon and Counselıng of Prostatectomy Patıents

Start date: July 10, 2022
Phase: N/A
Study type: Interventional

The research was planned as a randomized controlled experimental study. This study is planned to be conducted in the Urology clinic of a university hospital located in the south of Turkey. The population of the research will be the patients admitted to the urology clinic for prostatectomy. The sample of the study will consist of patients who meet the criteria for participation in the study and volunteer to participate in the study. Evaluation of the research data will be done with the SPSS package program.

NCT ID: NCT05421559 Completed - Surgery Clinical Trials

Transection of Sternothyroid Muscle Increases the Rate of Exposure of the External Laryngeal Nerve During Thyroidectomy

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

The sternothyroid (ST) muscle is closely adherent to the thyroid gland with oblique insertion into the thyroid cartilage. EBSLN passes through the sternothyroid laryngeal triangle with a parallel course deep to the ST muscle. This study evaluates the transection of the sternothyroid muscle as a key step during thyroidectomy to increase the rate of exposure and visual identification of EBSLN compared to ST muscle retraction as a traditional technique.

NCT ID: NCT05396703 Completed - Surgery Clinical Trials

TOETVA Feasibility and Complications - Single Center First Experience

Start date: October 22, 2019
Phase:
Study type: Observational

All participants who underwent (or will undergo) a transoral endoscopic thyroidectomy via vestibular approach (TOETVA) at the investigators' center are observed for complications and feasibility of this surgery. Anonymised data relevant to the participants' condition will be used.

NCT ID: NCT05389852 Completed - Surgery Clinical Trials

Analgesic Efficacy of Intravenous Dexmedetomidine for Supraclavicular Plexus Block

TwoDex
Start date: January 1, 2023
Phase: Phase 4
Study type: Interventional

The goal of the study is to compare the duration of analgesia in patients undergoing forearm or hand surgery with a supraclavicular brachial plexus block, who receive either iv dexmedetomidine or placebo.

NCT ID: NCT05386940 Completed - Surgery Clinical Trials

Protein Kinase N1 Level in Patients Undergoing Cardiac Surgery

Start date: July 22, 2019
Phase:
Study type: Observational [Patient Registry]

Acute kidney injury (AKI) is one of the most frequent major complications in patients undergoing cardiac surgery. CSA-AKI is independently related to increased perioperative mortality, increased hospital and ICU length of stay as well as heath care expenditure. Identification of relevant biomarkers may lead to early diagnosis and improve patient outcomes and health care costs. The pathophysiology of CSA-AKI is complex and ischemia-reperfusion injury is one of the important factors. Recently, it has been shown that Protein kinase N1 (PKN1) is associated with ischemia-reperfusion injury. In this study, relationship between PKN1 with the risk of CSA-AKI was analyzed and the predictive value of elevated level of PKN1 for early prediction of CSA-AKI was further evaluated.

NCT ID: NCT05374096 Completed - Anxiety Clinical Trials

Study Exploring the Effect of Music on Pain After Ventral Hernia Surgery

Start date: June 13, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to assess whether listening to music during surgery has an effect on pain or anxiety after surgery.

NCT ID: NCT05360355 Completed - Surgery Clinical Trials

Flap Fenestration and Facial Organ Fabrication Guided by ICGA

Start date: June 1, 2018
Phase:
Study type: Observational

In this retrospective study, patients with severe head and neck deformity were treated with monoblock pre-expanded prefabricated flaps for total face restoration. The opening of nostrils, oral and palpebral orifices, together with organ fabrication, were conducted under the guidance of intraoperative ICGA for hemodynamic evaluation. The hemodynamic analysis of flap perfusion before and after fenestration. Postoperative follow-up including vascular crisis, infection, flap necrosis and patients' aesthetic and functional recovery.