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Surgery clinical trials

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NCT ID: NCT02679859 Not yet recruiting - Surgery Clinical Trials

B-type Natriuretic Peptide Guided Therapy to Improve Clinical Outcomes for Patients Undergoing Non-cardiac Surgery

BETTER pilot
Start date: July 2016
Phase: N/A
Study type: Interventional

The primary hypothesis of the BETTER pilot trial is that B-type natriuretic peptide (BNP) directed medical therapy prior to noncardiac surgery will be associated with improved cardiovascular outcomes, when compared to standard of care.

NCT ID: NCT02563158 Not yet recruiting - Surgery Clinical Trials

Study of Liver Resection With Versus Without Hepatic Inflow Occlusion for the HBV-related HCC

OHx-NOHx
Start date: January 2016
Phase: N/A
Study type: Interventional

The study aims to compare the two liver resection techniques (with versus without hepatic inflow occlusion) in regards to perioperative and long-term outcomes of hepatectomy for HBV-related HCC.

NCT ID: NCT02372500 Not yet recruiting - Colorectal Cancer Clinical Trials

Trial of Chewing Gum to Reduce Post Operative Ileus in Elective Colorectal Surgery

Start date: March 2015
Phase: N/A
Study type: Interventional

It is unknown whether post operative chewing gum will reduce post operative ileus. This study is a randomised controlled trial that will determine whether chewing gum three times a day following surgery will reduce post operative ileus. Time to passage of flatus will be used to determine that incidence of ileus.

NCT ID: NCT02336152 Not yet recruiting - Surgery Clinical Trials

Use of Onepiece Suit or Forced Warm Air for Perioperative Temperature Conservation.

Start date: January 2015
Phase: N/A
Study type: Interventional

To study if a one piece body suite (T-balance, Telespro, Finland) is equally effective in maintaining peri-operative body temperature as forced air warming, during open low-back surgery of medium duration.

NCT ID: NCT01833286 Not yet recruiting - Clinical trials for Hepatocellular Carcinoma

TACE+RFA Versus Re-resection for Recurrent Small Hepatocellular Carcinoma

TACE-RFA
Start date: July 2013
Phase: Phase 3
Study type: Interventional

Hepatocellular carcinoma (HCC) is the fifth most common cancer in the world. Partial hepatectomy is still considered as the conventional therapy for HCC. Intrahepatic recurrence of HCC after partial hepatectomy is common and was reported to be more than 77% within 5 years after surgery. Repeat hepatectomy is an effective treatment for intrahepatic HCC recurrence, with a 5-year survival rate of 19.4-56%. This is comparable to the survival after initial hepatectomy for HCC. Unfortunately, repeat hepatectomy could be carried out only in a small proportion of patients with HCC recurrence (10.4-31%), either because of the poor functional liver reserve or because of widespread intrahepatic recurrence. In the past two decades, percutaneous radiofrequency ablation (PRFA) has emerged as a new treatment modality and has attracted great interest because of its effectiveness and safety for small HCC (≤ 5.0 cm). Studies using PRFA to treat recurrent HCC after partial hepatectomy reported a 3-year survival rate of 62-68%, which is comparable to those achieved by surgery. PRFA is particularly suitable to treat recurrent HCC after partial hepatectomy because these tumors are usually detected when they are small and PRFA causes the least deterioration of liver function in the patients. Our previous retrospective study demonstrated that RFA was comparable to re-resection for recurrent HCC, and our recent RCT showed that RFA combined with TACE is superior to RFA for HCC ≤7.0cm. So our hypothesis is that RFA combined with TACE is superior to re-resection for recurrent small HCC. The aim of this retrospective study is to compare the outcome of reresection with TACE+RFA for small recurrent HCC after partial hepatectomy.

NCT ID: NCT01706640 Not yet recruiting - Surgery Clinical Trials

An Open Label,Observational, Real Time Data Capturing of Usage & Outcome of Coseal

Start date: December 2012
Phase: N/A
Study type: Observational

This study is Open- Label, Observational, Prospective, Real-time data capturing of Usage, Outcome & Physician satisfaction of Coseal in Cardio- Vascular-Thoracic Operative and Re- Operative procedures. Objective of this study is to assess current practice pattern and best practice sharing of usage of Coseal by collecting data on (1) Sealing suture lines along arterial and venous reconstruction(2) Patients undergoing cardiac surgery to prevent or reduce the incidence, severity and extent of post surgical adhesion enforcement of suture lines in lung resection procedures (3) From this data to document and generate a real life experience on the use of Coseal in cardio vascular and thoracic surgery. Number of expected patient enrollment is 750 from 20 participating sites.

NCT ID: NCT01441453 Not yet recruiting - Clinical trials for Hepatocellular Carcinoma

Transient Elastography in Hepatectomy for Hepatocellular Carcinoma

Start date: n/a
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether liver transient elastography performed before the surgical procedure is able to predict liver failure in patients undergoing hepatectomy for hepatocellular carcinoma.

NCT ID: NCT00947401 Not yet recruiting - Surgery Clinical Trials

Fluid Management After Surgery in the Post-Anesthetic Care Unit (PACU)

Start date: September 2009
Phase: N/A
Study type: Observational

The objective of the present study is to describe the current practice of postoperative fluid management in the Post Anesthesia Care Unit (PACU) of the Shaare Zedek Medical Center, Jerusalem, Israel.

NCT ID: NCT00355693 Not yet recruiting - Surgery Clinical Trials

Effect Site Controlled, Reaction Time Safeguarded, Patient Maintained Sedation With Propofol in Anxious Patients

Start date: October 2006
Phase: Phase 4
Study type: Interventional

Whether patient-maintained sedation (the patient controls his/her degree of sedation using a hand-held device) using the drug propofol is safer and more effective when using deteriorating reaction time as an added safeguard against the potential for over sedation in a groups of patients undergoing oral surgery, general dentistry and colonoscopy.