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White Matter Integrity According to BDNF Genotype After Stroke

Stroke Clinical Trial

Official title:
Changes of White Matter Integrity According to BDNF Genotype During Motor Recovery After Stroke

Clinical Trial Summary

The aim of this study was to investigate differential plastic changes of fractional anisotropy (FA) in the corticospinal tract (CST), the intrahemispheric corticocortical tract from the primary motor cortex to ventral premotor cortex (M1PMv) and the corpus callosum (CC) from 2 weeks to 3 months after stroke according to BDNF genotype.

Clinical Trial Description

The aims of this study were to investigate plastic changes in the fractional anisotropy (FA) of three motor-related white matter fibers according to the BDNF genotype from 2 weeks to 3 months after stroke onset; one is a the majority of fibers from M1 to medullary oblongata (CST), another is the intrahemispheric connection from M1 to ventral premotor cortex (M1PMv), and the other is the interhemispheric connection between bilateral M1s (CC). There were also to investigate the relationships between motor impairment and tract-related FA of white matter tracts in each BDNF genotype ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03647787
Study type Observational
Source Samsung Medical Center
Contact
Status Completed
Phase
Start date May 25, 2018
Completion date April 5, 2019
View Details
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