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Biological Bank for Atrial Fibrillation and Stroke — BAFA  

Stroke Clinical Trial

Official title:
Biological Bank for Studies Related to Atrial Fibrillation and Stroke

Clinical Trial Summary

Atrial fibrillation (AF) is the most common cardiac arrhythmia encountered in clinical practice. This arrhythmia is responsible for 15% of strokes and more than 30% of strokes on people over 65 years. According to studies, 30 to 40% of isolated atrial fibrillations could be familial. Atrial fibrillation has significant genetic heterogeneity. About 40 genes have been identified as potentially involved. Studies have identified genes common to the risk of atrial fibrillation and stroke. Despite the pathophysiology of atrial fibrillation has been intensively and extensively studied for almost a century, there are still many questions. The pathophysiology is not sufficiently understood to allow finding more effective therapies. It is necessary to identify genetic determinants and thus potentially new pharmacological targets more adapted. The establishment of a biological database will test hypotheses concerning the genetic origin and thromboembolic process of atrial fibrillation and associated stroke.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03611816
Study type Observational
Source Hospices Civils de Lyon
Contact Philippe CHEVALIER, PU-PH
Phone 04 72 35 70 27
Email philippe.chevalier@chu-lyon.fr
Status Recruiting
Phase
Start date April 23, 2018
Completion date April 23, 2029
View Details
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