Postoperative Atrial Fibrillation and Long-term Survival

Stroke Clinical Trial

— POAF  

Official title:

Postoperative Atrial Fibrillation After Cardiac Surgery is Not an Independent Risk Factor for Long-term Cardiovascular Morbidity and Mortality in Anticoagulated Patients

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02349269
• Other study ID #: samuelm1
• Status: Completed
• Phase: N/A
• First received: December 1, 2014
• Last updated: January 23, 2015
• Start date: January 2012
• Est. completion date: September 2014

Study information

• Verified date: November 2014
• Source: Kuopio University Hospital
• Contact: n/a
• Is FDA regulated: No
• Health authority: Finland: Ministry of Social Affairs and Health
• Study type: Observational [Patient Registry]

Clinical Trial Summary

The aim of the investigators trial was to evaluate association between new onset postoperative atrial fibrillation (POAF) and late cardiovascular morbidity and mortality.

Description:

The material of this retrospective study consist patients without preoperative history of atrial fibrillation, participated in three different randomized controlled trials previously . A total of 519 consecutive patients underwent coronary artery bypass surgery, aortic valve replacement or combined aortic valve with coronary bypass surgery in Kuopio University Hospital from 2004 to 2008. Patients with previous episodes of atrial fibrillation (AF) or flutter and also patients with mitral valve surgery were excluded. All patients had continuous postoperative ECG monitoring for at least 48 hours. AF episodes lasting longer than 5 minutes were registered. Thereafter 12 lead ECG was recorded daily and in case of symptoms of rhythm disturbances.

Medical records were reviewed during 2012 using standardized data collection protocol. Statistics Finland database was used for mortality data.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 519
• Est. completion date: September 2014
• Est. primary completion date: December 2012
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• previously cardiac operation, CABG or AVR

Exclusion Criteria:

• Previous Atrial fibrillation

Study Design

N/A

Related Conditions & MeSH terms

• Atrial Fibrillation
• Death
• Myocardial Infarction
• Stroke

Locations

Country	Name	City	State
n/a

Sponsors (2)

Lead Sponsor	Collaborator
Kuopio University Hospital	University of Eastern Finland

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	cardiovascular and all-cause death		1-105 month	No
Primary	stroke		1-105 month	No
Primary	late atrial fibrillation		1-105 month	No
Primary	myocardial infarction		1-105 month	No