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Safety Study of RP-1127 (Glyburide for Injection) in Healthy Volunteers

Stroke Clinical Trial

Official title:
A Phase I Randomized, Double-Blind, Placebo-Controlled Study to Assess the Safety, Tolerability, and Pharmacokinetics of Escalating Doses of RP-1127 (Glyburide for Injection) in Healthy Male and Female Volunteers

Clinical Trial Summary

The primary objective of this study is to evaluate the safety and tolerability of different dose levels of glyburide for injection, administered as a bolus dose followed by a 3-day continuous infusion. The secondary objectives are to assess the pharmacokinetics (PK) of glyburide and blood glucose and serum insulin pharmacodynamic (PD) responses to glyburide.

Clinical Trial Description

This study was previously posted by Remedy Pharmaceuticals, Inc. and has since been acquired by Biogen. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01132703
Study type Interventional
Source Biogen
Contact
Status Completed
Phase Phase 1
Start date January 7, 2010
Completion date May 7, 2010
View Details
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