Treatment for Word Retrieval Impairments in Aphasia

Stroke Clinical Trial

Official title:

Communication Outcomes for Naming Treatments in Aphasia

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00764400
• Other study ID #: R15DC009690
• Secondary ID: 3R15DC009690
• Status: Completed
• Phase: N/A
• First received: September 30, 2008
• Last updated: April 4, 2018
• Start date: August 2008
• Est. completion date: July 2013

Study information

• Verified date: April 2018
• Source: Old Dominion University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

In this study the investigators are examining the effectiveness of two different speech therapy protocols for word retrieval impairments experienced by individuals with stroke-induced aphasia. One treatment involves errorless naming treatment and the other employs verbal plus gestural facilitation of word retrieval. Participants will receive one of the two treatments over several months. Before and after treatment the investigators will administer several tests and conversational samples to examine changes associated with the treatments. The investigators hypothesize that, whereas both treatments will lead to improvements in words rehearsed in therapy, communication outcomes in conversation will be broader for the verbal plus gestural protocol.

Description:

In this study the investigators are examining the effectiveness of two different speech therapy protocols for word retrieval impairments experienced by individuals with stroke-induced aphasia. One treatment involves errorless naming treatment and the other employs verbal plus gestural facilitation of word retrieval. Participants will receive one of the two treatments over several months. Before and after treatment the investigators will administer several tests and conversational samples to examine changes associated with the treatments. The investigators hypothesize that, whereas both treatments will lead to improvements in words rehearsed in therapy, communication outcomes in conversation will be broader for the verbal plus gestural protocol.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 24
• Est. completion date: July 2013
• Est. primary completion date: June 2013
• Accepts healthy volunteers: No
• Gender: All
• Age group: 21 Years to 90 Years

Eligibility

Inclusion Criteria:

• left hemisphere stroke >4 months earlier

• aphasia with word retrieval impairments

• >21 years of age right handed

• speaker of English as the preferred language

• >6 grade education

Exclusion Criteria:

• history of developmental learning difficulties

• history of prior neurological illnesses

• chronic medical illnesses that restrict participation in speech therapy

• alcohol or drug dependence

• severe uncorrected impairments of vision or hearing

Related Conditions & MeSH terms

• Aphasia
• Stroke

Intervention

Behavioral:
• Word Retrieval Treatments for Aphasia
Speech therapy sessions take place 4 times per week for up to 90 minutes per session. Following a phase of baseline pre-testing, two phases of speech therapy will take place lasting up to 20 sessions per phase. Post-testing will take place immediately upon completion of the treatment phases and again at 1 month post study completion.

Locations

Country	Name	City	State
United States	Old Dominion University Speech and Hearing Clinic	Norfolk	Virginia

Sponsors (2)

Lead Sponsor	Collaborator
Old Dominion University	National Institute on Deafness and Other Communication Disorders (NIDCD)

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Daily Probe Picture Naming		daily probes from three times per week for up to 3 months and one month posttreatment
Secondary	Western Aphasia Battery		pre-treatment and at treatment completion
Secondary	Boston Naming Test		pretreatment and at treatment completion
Secondary	Discourse Sample		pre-treatment and at treatment completion