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Aphasia clinical trials

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NCT ID: NCT06368323 Recruiting - Aphasia Clinical Trials

Effect of Community Choir Singing in People With Chronic Post-stroke Aphasia

Start date: April 22, 2024
Phase: N/A
Study type: Interventional

The goal of this randomized controled trial is to test the effects of assigning people with chronic post-stroke aphasia to 12 weekly choir sessions, compared to usual care. The main question it aims to answer is: Does the assignment to a choir singing program causes a beneficial effect on functional communication and language recovery as well as psychosocial outcomes compared to usual care in the rehabilitation of people with chronic post-stroke aphasia? Participants will have: 12 in-person choir-singing sessions (1 session/week, 1,5 h/session, total 18h) conducted by a choir master, and home singing training (3 x 30-minutes-sessions/week, total 18h)

NCT ID: NCT06365658 Recruiting - Aphasia Clinical Trials

Cognitive Functioning in Adults With Somatic Diseases and General Population From a Biopsychosocial Perspective

Start date: July 3, 2023
Phase:
Study type: Observational

The goal of this observational study is to investigate cognitive functioning profiles in adults with neurologically recognized aphasic syndromes and general population. The study group consist of minimal 600 adults (over 18 y.o.) who will be examined by qualified diagnosticians. Participants will be evaluated with tasks related to the studied variables: memory, learning and language. Furthermore informations regarding past and present health condition will be collected from participants. The main questions it aims to answer are: 1. What is the profile of memory and learning among polish adults? 2. Do gender and age moderates patterns of memory and learning functioning among polish adults? 3. What is a specific pattern of language functioning in adults with neurologically recognized aphasic syndromes? 4. Do gender moderates specific patterns of language functioning in adults with neurologically recognized aphasic syndromes? Researchers will compare the following groups of adults: 1. general population/control group 2. with neurologically recognized aphasic syndromes 3. seniors (over 60 y.o.)

NCT ID: NCT06364709 Not yet recruiting - Aphasia Clinical Trials

Criterion-learning Based Naming Treatment in Aphasia

Start date: May 15, 2024
Phase: N/A
Study type: Interventional

Aphasia is a disorder of spoken and written language, most commonly following a stroke. It is estimated that between 2.5 and 4 million Americans are living with aphasia today. A common problem in aphasia involves difficulty retrieving known words in the course of language production and comprehension. The overarching goal of this project is to develop and test early efficacy, efficiency, and the tolerability of a lexical treatment for aphasia in multiple-session regimens that are comprised of retrieval practice, distributed practice, and training dedicated to the elicitation of correct retrievals. The aim of this work is to add to and refine the evidence base for the implementation and optimization of these elements in the treatment of production and comprehension deficits in aphasia, and make important steps towards an ultimate goal of self-administered lexical treatment grounded in retrieval practice principles (RPP) to supplement traditional speech-language therapy that is appropriate for People with Aphasia (PWA) from a broad level of severity of lexical processing deficit in naming and/or comprehension. This project cumulatively builds on prior work to develop a theory of learning for lexical processing impairment in aphasia that aims to ultimately explain why and for whom familiar lexical treatments work, and how to maximize the benefits they confer.

NCT ID: NCT06361901 Recruiting - Stroke Clinical Trials

Comparison of Therapeutic Effect Between Speech Rehabilitation Program and Speech Therapy in Stroke Patients With Aphasia

Start date: November 17, 2023
Phase: N/A
Study type: Interventional

Our study will provide precise and intensive speech rehabilitation treatment program to patients with speech disorders after stroke, and compare clinical evaluations with the conventional speech therapy patient group. Clinical evaluation tools will be performed before and after the treatment for all patients - K-Western Aphasia Battery for aphasia assessment tools - Cerebral blood flow changes with near-infrared spectroscopy

NCT ID: NCT06323629 Not yet recruiting - Stroke Clinical Trials

Effects of Recursive Self-feedback on Speech Production in Aphasia

Start date: April 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to test the effects of recursive self-feedback procedures on spontaneous speech production in stroke survivors with impaired speech production (aphasia). The main question it aims to answer is: • To what extent can stroke survivors with aphasia use their self-feedback alone to improve their spontaneous speech production? Participants will be engaged in the following activities: - They will perform language and cognitive tasks. - Afterwards, they will receive treatments using tablets and headphones at no cost to them. - The experimental treatments (recursive self-feedback procedures) entails responding to prompts, listening to playbacks of their speech response and attempt to minimize/correct the errors in the next attempt. This process will be repeated multiple times per prompt. - The experimental treatments are two: an adaptive version that adapts the complexity of the treatment prompt and a non-adaptive version that does not adapt task complexity. - Researchers will compare the experimental treatments to see if both have similar effects on improving spontaneous speech production.

NCT ID: NCT06323330 Not yet recruiting - Clinical trials for Stroke Rehabilitation

Music Therapy for Rehabilitation in Post-stroke Non-fluent Aphasia: the Indian Adaptation

Start date: April 1, 2024
Phase: N/A
Study type: Interventional

The goal of this Interventional Study is to develop and test the Indian Adaptation of Melodic Intonation Therapy (MIT) for Indian patients in with post-stroke Non-Fluent Aphasia (PSNFA). The main question[s] it aims to answer are: • To develop the MIT Indian Adaptation tool and check its feasibility • To compare the MIT with standard speech rehabilitation in patient with PSNFA. Participants will undergo Speech Rehabilitation according to the developed module and the standard treatment will be given in the comparator arm. The speech recovery at 12 weeks will be compared in both treatment arms.

NCT ID: NCT06213376 Enrolling by invitation - Stroke Clinical Trials

MIT Intensive Treatment Study

MITTXS
Start date: December 28, 2023
Phase: N/A
Study type: Interventional

This study is examining the use of intensive melodic intonation therapy and video feedback as a means of aiding individuals with nonfluent aphasia and co-occurring motor speech impairments. Individuals with nonfluent aphasia have difficulty with language, particularly with word retrieval.

NCT ID: NCT06213272 Not yet recruiting - Stroke Clinical Trials

Combined Exercise and Targeted Therapy for Post-Stroke Reading Deficits

Start date: October 1, 2024
Phase: N/A
Study type: Interventional

The goal of the proposed project is to test the effectiveness of a novel hybrid approach to treatment of reading disorders after stroke, in which exercise training will be used in combination with a targeted reading treatment. This approach is expected to increase cerebral circulation and help to rebuild and strengthen the damaged phonological neural networks. Through this combinatory approach, the study aims to enhance the reading and language improvements seen with existing treatments.

NCT ID: NCT06211374 Not yet recruiting - Clinical trials for Primary Progressive Aphasia

Communication Bridge Pilot Study

CB3_1
Start date: April 1, 2024
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the effectiveness and feasibility of evidence-based interventions in individuals living with mild to moderate primary progressive aphasia (PPA) that address communication-focused outcomes.

NCT ID: NCT06200025 Completed - Stroke, Ischemic Clinical Trials

Virtual Reality in Aphasia Rehabilitation

Start date: October 15, 2021
Phase: N/A
Study type: Interventional

Virtual reality-based aphasia rehabilitation has been shown to improve the language skills of individuals with aphasia in the chronic period after stroke. However, non-immersive or semi-immersive rehabilitation methods have often been adopted in the studies. Considering the importance of the visual given to the patient for naming, it can be thought that full immersive therapy may be more effective. Therefore, the aim of this study was to investigate the effect of cue-based aphasia naming therapy in a fully immersive virtual reality environment on aphasia severity and aphasia-related quality of life and to compare it with standard cue treatments.