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Transcranial Direct Current Stimulation as a Neuroprotection in Acute Stroke — TESSERACT  

Stroke, Acute Clinical Trial

Official title:
Transcranial Electrical Stimulation in Stroke EaRly After Onset Clinical Trial

Clinical Trial Summary

This proposal is a prospective, single-center, dose-escalation safety, tolerability, feasibility and potential efficacy study of transcranial direct current stimulation (tDCS) in acute stroke patients with substantial salvageable penumbra due to a large vessel occlusion who are ineligible for intravenous thrombolysis and endovascular therapy.

Clinical Trial Description

This is a single center, sham-controlled, dose escalation study where cathodal tDCS is delivered to threatened but not yet irreversibly damaged (penumbral) tissue in patients with large vessel occlusion who are not eligible for blood flow restoring recanalization procedures. Patients will be randomized in a 3:1 design, to cathodal versus sham (control) stimulation, at each six designed dose tiers. The dose tiers will be increasing in both intensity and duration of the stimulation. The occurrence of symptomatic intracranial hemorrhage will determine the pace of the escalation through the dose tiers. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03574038
Study type Interventional
Source University of California, Los Angeles
Contact
Status Completed
Phase N/A
Start date September 28, 2018
Completion date April 1, 2022
View Details
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