Carotid Duplex Ultrasound for Selecting Patients for Endovascular Thrombectomy in Acute Stroke Patients

Stroke, Acute Clinical Trial

— ECHO-SELECT  

Official title:

Emergent Carotid Ultrasound in Hyperacute Cerebral Vessel Occlusion for Selecting Patients to be Treated With Endovascular Clot Retrieval Treatment

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02989376
• Other study ID #: KohnanSN01
• Status: Completed
• Phase: N/A
• Start date: October 2016
• Est. completion date: October 30, 2019

Study information

• Verified date: February 2020
• Source: Kohnan Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The aim of this study is to address the usefulness of carotid duplex ultrasound as vascular imaging for selecting acute stroke patients for endovascular thrombectomy.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 40
• Est. completion date: October 30, 2019
• Est. primary completion date: June 30, 2019
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Endovascular treatment can be initiated within 6 hours of symptom onset.

• ASPECTS of >=6 is diagnosed by two or more stroke physicians.

• The end diastolic velocity in the common carotid arteries or internal carotid artery is evaluated by carotid duplex ultrasound

• NIHSS score of >=6.

• Age>=18 years.

• Written informed consent is obtained.

Exclusion Criteria:

• Pre-stroke modified Rankin Scale (mRS) score >=2.

• Difficulties to evaluate ASPECTS on initial CT.

• Difficulties to groin puncture.

• History of severe allergic reaction to contrast medium.

• End stage renal disease.

Related Conditions & MeSH terms

• Stroke
• Stroke, Acute

Intervention

Procedure:
• After detection of occluded vessels by vascular imaging using carotid duplex ultrasound, digital subtraction angiography is immediately performed before acute endovascular treatment.
When the ratio of the end diastolic velocity in the common carotid arteries is greater than 1.4 or the diastolic flow in the internal carotid artery is not detected by vascular imaging using carotid duplex ultrasound, digital subtraction angiography is immediately performed before acute endovascular treatment. If vessel occlusion is not detected by carotid duplex ultrasound, additional vascular imaging including MR angiography or CT angiography is considered.

Locations

Country	Name	City	State
Japan	Kohnan hospital	Sendai	Miyagi

Sponsors (1)

Lead Sponsor	Collaborator
Ryo Itabashi

Country where clinical trial is conducted

Japan, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	modified Rankin Scale		at 90 days after onset