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Stress, Psychological clinical trials

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NCT ID: NCT02394899 Completed - Sickle Cell Disease Clinical Trials

Improving Parental Psychosocial Functioning and Early Developmental Outcomes in Children With Sickle Cell Disease

Start date: October 2014
Phase: N/A
Study type: Interventional

There are all significant risk factors for poor early cognitive development and, as such, neurocognitive deficits have been demonstrated in pre-school children with sickle cell disease (SCD). This project assesses the efficacy of using an evidence-based early stimulation program, combined with components to help parents cope with stress, delivered during six routine monthly clinic visits to parents of children with sickle cell disease. It is hoped that this innovation will improve parental psychological outcomes, as well as child developmental outcomes.

NCT ID: NCT02386878 Completed - Clinical trials for Stress, Psychological

HIV/AIDS Orphaned and Vulnerable Children Public Health Evaluation

PHE
Start date: January 2012
Phase: N/A
Study type: Interventional

The PHE study is a two-year longitudinal study evaluating two interventions for reducing depression and HIV risk behaviors among highly vulnerable adolescents in the Eastern Cape of South Africa. Research suggests that children affected by AIDS are at heightened risk of HIV infection relative to their peers; however, evidence on how best to address HIV prevention and psychological health among this population is lacking. This study examines the efficacy of both a psychological and behavioral intervention, alone and in combination, on related outcomes among vulnerable youth age 14-17. A mixed methods approach is applied, including a community-randomized controlled trial with a factorial design, a cost-effectiveness analysis, and a qualitative component. At baseline data collection in January 2012, more than 1000 adolescents and their caregivers were interviewed; these participants were invited to take part in two more survey rounds designed to examine both the immediate and long term effects of the interventions. Support for this research was provided by USAID under Grant No. GHH-I-00-007-00069-00.

NCT ID: NCT02378610 Completed - Clinical trials for Psychological Stress

Relationship Between the Gut Microbiota and Stress

Start date: February 2015
Phase: N/A
Study type: Observational

The relationship between the gut microbiota and stress is poorly studied in humans. In this study we aim to look for if stressed persons have different levels of key bacterial groups compared to the levels in non-stressed persons.

NCT ID: NCT02378597 Completed - Clinical trials for Psychological Stress

Resiliency Program for Medical Interpreters

CARE
Start date: January 2014
Phase: Phase 1/Phase 2
Study type: Interventional

To develop and test a 4-session program to teach resiliency skills to Medical Interpreters.

NCT ID: NCT02347748 Completed - Pain Clinical Trials

Comfort Talk for Pediatric Cardiac Catheterization

Start date: January 2015
Phase: N/A
Study type: Interventional

Background: Pre anaesthesia anxiety in children is a strong predictor of postoperative behavior challenges and outcomes. In addition, intra-operative stress can precipitate post-traumatic stress symptomatology. Comfort Talk, consisting of rapport, relaxation, and reframing of potentially stressful experiences, applied pre-operatively in script form, has been highly successful in alleviating anxiety and positively affecting procedural outcomes in adult patients undergoing interventional procedures. No published literature exists evaluating its' impact in paediatric cardiac catheterization. Purpose: To investigate the impact of comfort talk on the level of pre-induction anxiety, procedural and recovery experience, as well as short-term post-procedural behaviour and satisfaction after discharge in pediatric patients undergoing cardiac catheterization procedures. Design: Prospective randomized, double blind controlled trial. Participants: 160 children, ages 7-18 years, having a cardiac catheterization procedure under general anaesthesia. Intervention: Group A will be read a pre-procedure comfort talk script in the pre-procedure work-up area; Group B will be read a pre-extubation (before the breathing tube is removed) script ; Group C will be read a pre-procedure plus a pre-extubation script; Group D will not be read any script. All groups will be treated according to the standard of care approaches usually provided for anaesthesia, catheterization, and recovery. Outcomes: We will compare the effect of the script strategy on preoperative anxiety. Procedural and recovery measurements will include room time in the catheterization suite, time to discharge from the recovery room; drug use, vomiting, rebleeds, and cardiorespiratory stability. Postoperative behaviour will be assessed by questionnaire. Postoperative anxiety and pain will be secondary outcome measures using queries on 0-10 verbal self-report scales Hypotheses are: 1. Patients being read a preoperative Comfort Talk script will experience less anxiety prior to anaesthesia induction. 2. The reduction of anxiety prior to induction is associated with better immediate and short-term recovery outcomes. 3. Patients being read a pre-extubation script will recover better than controls. 4. The combination of a pre-procedure script and a pre-extubation script will have the greatest positive effect on physical and emotional well-being in the immediate recovery period and at short term follow-up.

NCT ID: NCT02339363 Completed - Anxiety Clinical Trials

Effects of Sitting Meditation and Hatha Yoga in Adolescents

Start date: March 2013
Phase: Phase 1/Phase 2
Study type: Interventional

The present study was a randomized controlled trial that explored the feasibility, acceptability, and effectiveness of short-term mindfulness training among adolescents. The primary purpose was to investigate the effectiveness of two main Mindfulness-Based Stress Reduction components—sitting meditation and hatha yoga—on working memory, stress, anxiety and mindfulness. The influence of daily home practice compliance on intervention outcomes was also examined.

NCT ID: NCT02307019 Completed - Emotional Stress Clinical Trials

Intervention on Caregivers Caring for Patients Poststroke With Upper Limb Apraxia

CPA
Start date: July 2014
Phase: N/A
Study type: Interventional

The purpose of this study is to analyze the effects of a intervention on a specific health prevention/intervention program aimed at caregivers of mild and moderate patients post stroke with upper limb apraxia in comparison to a control group with a no specific formation in that kind of patients.

NCT ID: NCT02298530 Completed - Healthy Clinical Trials

Tea Components, Mental Stress and Blood Pressure

Start date: March 2015
Phase: N/A
Study type: Interventional

Assess the effects of adding theanine to a caffeinated beverage on changes in blood pressure during acute mental stress.

NCT ID: NCT02286115 Completed - Clinical trials for Chronic Urogenital Pain

Life-Stress Interview for Women With Chronic Urogenital Pain Conditions

Start date: September 2014
Phase: N/A
Study type: Interventional

The goal of this study is to test the efficacy, feasibility, and acceptability of providing an experiential assessment interview that targets health, and emotional and stressful experiences in a tertiary care setting specializing in women's urology.

NCT ID: NCT02257853 Completed - Clinical trials for Stress, Psychological

Effectiveness of a Stress Reduction Intervention in Caregivers of Allogeneic Hematopoietic Stem Cell Transplant (HSCT) Recipients

Start date: January 5, 2015
Phase: Phase 2
Study type: Interventional

Background: - People who have an allogeneic hematopoietic stem cell transplant (HSCT) need help as they recover. Being a caregiver can be stressful to the body and mind. Researchers want to find ways to reduce this stress. Objective: - To see how a stress reduction intervention affects the stress levels and health of an HSCT caregiver. Eligibility: - Adults age 18 and older who plan to be an active caregiver for a person having their first allogeneic HSCT at the NIH Clinical Center. An active caregiver is someone who will be caring for the person from just before admission for the HSCT until at least 6 weeks after. Design: - Participants will be put in either the intervention group or the control group. - All participants will get the usual caregiver education given to all patients and caregivers having a stem cell transplant at the NIH Clinical Center. - All participants will have 2 study visits. They will give blood samples. They will have health assessments and brief physical exams. They will fill out study questionnaires and have an exit interview. - The intervention group will get an MP3 player. It will have an audio file with a stress reduction intervention on it. Participants will do this intervention daily. It takes 20 minutes. They will do gentle stretches and breathing exercises. They will get a diary to track their practice. - The intervention group also will have follow-up phone calls 2 and 4 weeks after their first clinic visit. - The person getting the HSCT will not be actively involved in the study. - The study will last about 2 months....