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Smoking clinical trials

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NCT ID: NCT04025333 Completed - Smoking Clinical Trials

Helping Ethnic Minority in Hong Kong to Quit Smoking by Understanding Their Knowledge, Attitude and Behavior Related to Smoking

Start date: September 18, 2018
Phase:
Study type: Observational

This study aims at understanding the needs and concerns of the ethnic minority in Hong Kong, including their behavior, attitudes, and experiences related to smoking and smoking cessation. Specifically, how the level of smoking-related knowledge among them differ from the rest of the Hong Kong people, will be explored. In addition, whether Hong Kong smoking policy influenced the smoking pattern of them will be investigated.

NCT ID: NCT04009538 Completed - Copd Clinical Trials

Re-Rehabilitation in Chronic Obstrctive Pulmonary Disease

Start date: January 2013
Phase: N/A
Study type: Interventional

Patients with COPD who participated in the second rehabilitation program in the Pulmonary Rehabilitation unit will be included in the study. Pulmonary function tests, arterial blood gases, mMRC dyspnea perception, 6-minute walking distance, disease-specific (SGRQ) quality of life and hospital anxiety depression scale values will be compared.

NCT ID: NCT03999411 Completed - HIV Clinical Trials

Smartphone Intervention for Smoking Cessation and Improving Adherence to Treatment Among HIV Patients

Start date: September 9, 2019
Phase: Phase 4
Study type: Interventional

The purpose of this study is to learn if a mindfulness-based smoking cessation smartphone app can help people quit smoking and stay on antiretroviral therapies.

NCT ID: NCT03996902 Completed - Chronic Pain Clinical Trials

Increasing Cessation Motivation and Treatment Engagement Among Smokers in Pain

Start date: May 10, 2016
Phase: N/A
Study type: Interventional

The goal of this study is to develop and pilot test a brief intervention to increase motivation to quit and smoking cessation treatment engagement among smokers with chronic pain.

NCT ID: NCT03978455 Completed - Smoking Cessation Clinical Trials

A Pilot Study of the Learn, Connect, and Quit Mobile Application

Start date: June 18, 2019
Phase:
Study type: Observational

This research study aims to develop and test the effectiveness of a mobile application for patients who smoke to use while waiting in the clinic exam room to see their provider. The application will present patients with a variety of videos designed to increase their engagement in evidence-based smoking cessation treatment and offer them action steps to engage in smoking-related treatment or discussions with their provider.

NCT ID: NCT03978442 Recruiting - Smoking Clinical Trials

CPT-SMART for Treatment of PTSD and Cigarette Smoking

CPT-SMART
Start date: November 7, 2019
Phase: Phase 4
Study type: Interventional

Smoking is the leading cause of preventable illness, disability, and death in the United States. The rate of smoking is disproportionately higher among Veterans with posttraumatic stress disorder (PTSD). Unfortunately, smoking cessation efforts that are effective in the general population have shown limited effectiveness in smokers with PTSD. The high smoking rate and difficulty with achieving abstinence indicate a critical need to develop effective interventions for Veterans who smoke and have PTSD. The investigators' data indicate that negative emotions and trauma reminders are associated with relapse for smokers with PTSD. In this context, an ideal strategy may be to combine evidence-based PTSD treatment with intensive smoking cessation treatment to maximize quit rates. Cognitive processing therapy (CPT) is a well-established evidence-based treatment for PTSD. The investigators have successfully developed a treatment manual that combines CPT with cognitive-behavioral counseling for smoking cessation. Contingency management (CM) is another intensive behavioral treatment that has been shown to help with reducing smoking. CM provides positive reinforcers such as money to individuals misusing substances contingent upon abstinence from use. The primary goal of this study is to evaluate the efficacy of a treatment that combines CM with cognitive-behavioral smoking cessation counseling, smoking cessation medication, and CPT. Proposed is a randomized, two-arm clinical trial in which 120 Veteran smokers with PTSD will be randomized to either: 1) COGNITIVE PROCESSING THERAPY with SMOKING ABSTINENCE REINFORCEMENT THERAPY (CPT-SMART) or 2) COMBINED CONTACT CONTROL, an intervention identical to CPT-SMART in PTSD and smoking treatment, except for using payment that is not contingent on abstinence. Specific aims include: AIM 1) To evaluate the efficacy of CPT-SMART on rates of short- and long-term abstinence from cigarettes; AIM 2) To evaluate the impact of CPT-SMART on treatment engagement and utilization; and an EXPLORATORY AIM) To explore mechanisms of CPT-SMART on long-term smoking abstinence. The positive public health impact of reducing smoking among Veterans with PTSD could be enormous as it would prevent significant smoking-related morbidity and mortality.

NCT ID: NCT03968900 Recruiting - Smoking Clinical Trials

Racial Differences in Circadian and Sleep Mechanisms for Nicotine Dependence, Craving, and Withdrawal

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

The number one preventable cause of death in the world is tobacco use. Cigarette smoking in particular, costs an estimated $300 billion due to expenses related to medical care and lost productivity. Despite similar smoking prevalence rates, blacks suffer disproportionately from smoking-related harms compared to whites.Sleep disparities such as shortened sleep duration, shorter circadian periodicity, earlier chronotype, and increased variability of sleep timing have been reported more frequently in blacks compared to whites. Given that poor sleep quality predicts relapse from smoking cessation programs, particularly among socioeconomically disadvantaged adults, sleep deficiencies and irregular timing of sleep may impact smoking craving and withdrawal symptoms over the course of the 24-hour day. Surprisingly, few studies have examined these temporal patterns of smoking and craving, and none with regard to sleep disruption, chronotype or racial disparities. A better understanding of these factors may explain heterogeneity within the smoking population, especially in minorities. Thus, the purpose of this proposal is to test the central hypothesis that the impact of chronotype and impaired sleep on cigarette usage as well as smoking dependence, urge/craving, and withdrawal depends on race.

NCT ID: NCT03938584 Completed - Surgery Clinical Trials

The Effect of Vitamin C on Wound Healing In Mandibular Fracture Patients

Start date: October 12, 2017
Phase: N/A
Study type: Interventional

The goal of this study is to perform a randomized clinical trial to assess the effects of vitamin C versus placebo on wound healing in mandibular fracture patients.

NCT ID: NCT03931772 Completed - Pain Clinical Trials

Online Automated Self-Hypnosis Program

Start date: September 5, 2017
Phase: N/A
Study type: Interventional

After developing professional quality materials (audio) for an affordable automated self-hypnosis intervention program for facilitating smoking cessation, stress and pain reduction, researchers aim to gain qualitative reviews of this program, and test its initial feasibility and effects on smoking cessation and reduction in pain and stress. In addition, this study seeks to determine whether higher hypnotizability, as measured by the Hypnotic Induction Profile (assessed at baseline), is a moderator of improved outcome in these conditions.

NCT ID: NCT03920319 Completed - Smoking Clinical Trials

Bupropion and Cigarette-Related Cues in Smokers

Start date: January 1, 2004
Phase: Phase 1
Study type: Interventional

Randomized, double-blind, before-after controlled trial to assess changes in regional brain activation in response to cigarette-related cues from before to after treatment with bupropion (vs placebo).