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Smoking clinical trials

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NCT ID: NCT05952401 Enrolling by invitation - Smoking Cessation Clinical Trials

Implementation Science to Reduce the Disparity in Tobacco Treatment Among Individuals With Serious Mental Illness

ISRAISE
Start date: May 31, 2024
Phase: N/A
Study type: Interventional

This is a pilot trial to examine the feasibility and preliminary effect of a multilevel intervention 'Nudges to Quit' on smoking cessation in patients with serious mental illness who smoke in a community mental health center (CMHC). "Nudges to Quit" is a multilevel intervention to increate engagement of patient, case worker, and pharmacist with tobacco treatment. The pilot trial is to generate the needed evidence for designing a future large trial to evaluate the effect of 'Nudges to Quit' as a multilevel intervention to increase tobacco treatment and reduce tobacco use among patients with serious mental illness.

NCT ID: NCT05852860 Enrolling by invitation - HIV Clinical Trials

A Patient-Oriented Research Mentoring Program in Tobacco Dependence and Implementation Science Research

Start date: December 1, 2023
Phase: N/A
Study type: Interventional

The objective of this trial is to evaluate the effectiveness of "nudges" to clinicians, patients, or both in increasing referral to, and engagement with, tobacco use treatment services (TUTS) for HIV patients versus usual care. This will be a four-arm pragmatic cluster randomized clinical trial. The investigators hypothesize that each of the implementation strategy arms will significantly increase TUTS referral and engagement compared to usual care and that the combination of nudges to clinicians and to patients will be the most effective.

NCT ID: NCT05641974 Enrolling by invitation - Smoking Clinical Trials

Effect of Helpers Program On-line Training on Smoking Relapse and Social Networks

Start date: December 12, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the effect of the Helpers Stay Quit training on abstinence over time of newly abstinent smokers, and on the interactions they have with their personal network related to smoking and smoking cessation.

NCT ID: NCT05627674 Enrolling by invitation - Smoking Cessation Clinical Trials

Precision Prevention Strategy to Increase Uptake and Engagement in Lung Cancer Screening and Smoking Cessation Treatment

PRECISE
Start date: January 1, 2023
Phase: N/A
Study type: Interventional

This trial tests the effects of two versions of RiskProfile, a clinically-informed and a genetically-informed version of a patient-specific risk feedback tool, in comparison to usual care, on lung cancer screening and tobacco treatment. The trial assesses the multilevel effects of these precision risk feedback tools on the likelihood of clinicians to order lung cancer screening and tobacco treatment and of their patients to utilize these cancer prevention interventions.

NCT ID: NCT04938089 Enrolling by invitation - Smoking Clinical Trials

Effect of Periodontal Maintenance Therapy on Tooth Loss in Regular and Irregular Compliant Smokers and Non-Smokers: A Cohort Retrospective Analysis With a Follow-up Up to 40 Years

Start date: May 2022
Phase:
Study type: Observational

Periodontal diseases are infections cause by dental plaque (Socransky, 1970). Risk factors are present which modify the course of disease progression. One of these risk factors is tobacco smoking, which was first evaluated by Pindborg in 1947 and later by Grossi et al. in 1995. They found that tobacco smoking was strongly associated with attachment loss, bone loss, and lastly, tooth loss. Tooth loss in one of the most visible results of periodontal disease, which negatively affects physiological and psychological patient's life. The effects of cigarette smoking on periodontal status are independent of the plaque index and oral hygiene of the patient, due to the direct influence of tobacco on periodontal tissues. Several studies have demonstrated the effectiveness of periodontal therapy in reducing the rate of tooth loss as well as the importance of patient compliance with periodontal maintenance therapy and adequate oral hygiene practice in achieving this reduction. Compliance is the main problem faced in periodontal maintenance therapy. Low rates of compliance and patient adherence to a maintenance program was reported in the literature. Periodontal maintenance therapy can be considered a critical factor for success in controlling periodontitis and in the long-term maintenance of teeth. In addition, neglecting a regular periodontal maintenance therapy program has been associated with increased risk of reinfection and progression of periodontitis, as well as increased tooth loss. The establishment of a criteria for time interval between different supportive periodontal maintenance visits, is still controversial. Smokers are associated with low level of compliance to prevent being constantly reminded of quitting smoking as well as the health complications associated with the habit. There is a void in the literature addressing the direct influence of compliance and adherence in periodontal maintenance therapy and its contribution to arrest periodontitis progression, minimizing tooth loss, specifically in tobacco smoking patients, whether they are regular or irregular compliant with a long term follow-up up to 40 years. On the other hand, there is moderate scientific evidence that the independent effect of smoking is associated with the occurrence of tooth loss in individuals undergoing periodontal maintenance therapy. Lastly, only very few studies reported the specific outcome of periodontal maintenance therapy on tooth loss in regular and irregular compliant smokers compared to regular and irregular compliant non-smokers. The focused question in this study is "Does periodontal maintenance therapy affect annual tooth loss rates differently in regular and irregular compliant smokers and non-smokers?".

NCT ID: NCT04592302 Enrolling by invitation - Smoking Clinical Trials

The Impact of Smoking on Outcomes and Complications in Total Joint Arthroplasty: A Prospective Crossover Study

Start date: December 1, 2016
Phase:
Study type: Observational

The purpose of this study is to examine the impact of smoking cessation on total joint arthroplasty patients with respect to perioperative complications and outcomes. The investigators will examine patients who are asked to stop smoking in any manner they choose and also refrain from nicotine replacement therapy, and those who are allowed to continue smoking during the perioperative period for their total knee or total hip replacement.

NCT ID: NCT04462289 Enrolling by invitation - Clinical trials for Pulmonary Disease, Chronic Obstructive

Electronic Proactive Outreach for Smokers With COPD

Start date: September 1, 2020
Phase: N/A
Study type: Interventional

Chronic obstructive pulmonary disease (COPD) is one of the most common respiratory diseases, with 90% of cases directly attributable to smoking. Unfortunately, many patients continue to smoke and have an urgent need to quit. Proactive tobacco treatment programs identify patients outside of a routine clinical appointment and engage them in making a supported quit attempt. Most previous research of proactive tobacco treatment has used telephone outreach, which can be resource intensive. Electronic methods (texting, secure messaging) may be effective while requiring fewer resources. In this study, a previously tested telephone outreach intervention will be adapted for electronic delivery, with content tailored to smokers with COPD. First, information will be gathered from smokers with COPD and the medical staff who care for them to adapt the program for electronic delivery. Then, the program will be pilot-tested. Smokers with COPD will be randomly assigned to either usual medical care or the outreach intervention, with goals to increase participation in smoking cessation programs, quit attempts, and successful cessation.

NCT ID: NCT02932917 Enrolling by invitation - Smoking Clinical Trials

MapMySmoke: Smoking Cessation App With Geospatial Capture

Start date: June 2016
Phase: Phase 1
Study type: Interventional

Place-based cues can be an important trigger of smoking behavior, therefore the investigators wish to learn more about the influence of the built environment on individual smoking behavior. This is to facilitate dynamic support during the post-quit phase. MapMySmoke is a mobile phone application that enables the capture of spatial data during smoking and craving events. These data will be used to create individualized support plans via the app.

NCT ID: NCT00906386 Enrolling by invitation - Smoking Clinical Trials

Methadone Maintenance Treatment and Smoking Cessation

MMTASC
Start date: May 2009
Phase: Phase 2
Study type: Interventional

The main hypotheses guiding the study are: 1. Stable methadone maintenance patients receiving varenicline will be more likely to maintain abstinence than patients receiving placebo 2. There will be no differences in the type and number of symptoms reported between stable methadone maintenance patients receiving varenicline and placebo 3. There will be no changes in methadone dosage between abstinent and non-abstinent smokers 4. There will be no differences in efficacy, withdrawal symptoms, and safety of varenicline between male and female participants