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Smoking Cessation clinical trials

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NCT ID: NCT06111053 Recruiting - Obesity Clinical Trials

Trial for Harm Reduction With Incentives & Vaping E-cigarettes

THRIVE
Start date: October 2, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to provide preliminary information on the effect of electronic nicotine delivery systems (ENDS) provisions and contingent incentives (CI) on smoking in individuals with overweight/obesity who smoke cigarettes (SWO). All participants will be provided information on the comparative risk of ENDS relative to cigarette smoking, and a randomized group of participants will be provided ENDS provisions for 6 weeks. All participants will complete breath samples for 28 days to measure their exhaled carbon monoxide and will either receive fixed incentives for sample completion or receive varying incentives contingent on their carbon monoxide levels. Researchers will compare groups to understand the effect of each condition on smoking-related behavior.

NCT ID: NCT06098144 Recruiting - Smoking Cessation Clinical Trials

Smoking Cessation Program in the Construction Sector

Start date: April 10, 2024
Phase: Phase 4
Study type: Interventional

The main objective of this study is to identify the optimal adaptive smoking cessation program for the construction sector in terms of effectiveness, cost-effectiveness, and potential implementation.

NCT ID: NCT06087328 Recruiting - Smoking Cessation Clinical Trials

CAN-DOSE Study: Cessation With Augmented Nicotine for Dual Use Of Smoking and E-cigarettes

CAN-DOSE
Start date: December 5, 2023
Phase: Phase 2
Study type: Interventional

Many people smoke cigarettes and use e-cigarettes, and have a hard time stopping. Nicotine replacement therapy medications, such as nicotine patches and lozenges, have been shown to help people quit e-cigarette use. The purpose of the present study is to see how well nicotine patches and lozenges help people quit both smoking and vaping, and to determine if higher doses of the medication work best.

NCT ID: NCT06077058 Recruiting - Smoking Cessation Clinical Trials

Quit Smoking: Optimizing Health Promotion Strategy

Start date: June 1, 2023
Phase: N/A
Study type: Interventional

The goal of this factorial trail is to to optimize an intervention package to enhance quit attempt preparations, quit attempts, and tobacco abstinence among smokers without a plan to quit. The main questions it aims to answer are: - What are the main effects of the four intervention components for increasing quit attempt preparation? - Are there synergistic or antagonistic interactions between components? - Does chat-based instant message or chatbot enhance the effects of nicotine replacement therapy sampling and/or simple exercise education in increasing motivation to quit? - When participants experienced successful quitting by using the nicotine replacement therapy patch, will other tools, such as simple exercise education, chat-based instant messages, or chatbot, could help in the process and strengthen the effects of the nicotine replacement therapy patch and solve the possible problems they may encounter in using nicotine replacement therapy patch in a timely manner?

NCT ID: NCT06051474 Recruiting - Smoking Cessation Clinical Trials

Treating Caregivers Who Smoke at AFCH

Start date: March 5, 2024
Phase: Phase 4
Study type: Interventional

The purpose of this research study is to 1) see if a smoking cessation program is something that caregivers will use while their child is hospitalized, 2) see if caregivers think this program is something we should institute across the hospital, and 3) see if this program can help caregivers reduce their smoking. Participants will: - Complete a survey regarding smoking behavior and thoughts about quitting; - Undergo a 20-minute counseling session; and, - Use nicotine patches and mini-lozenges for 2 weeks

NCT ID: NCT06027840 Recruiting - Smoking Cessation Clinical Trials

Concurrent vs. Sequential Cessation of Dual Cigarette and E-cigarette Use

Start date: April 1, 2024
Phase: Phase 1
Study type: Interventional

The purpose of this research study is to understand whether concurrent treatment for cigarettes and e-cigarettes in which an individual quits both products at the same time (QUIT-C) or sequential treatment in which an individual quits cigarettes first followed by e-cigarettes is more effective for quitting both products. The study will also compare the effect of treatment on health-related biomarkers. All participants will receive varenicline, a medication used to treat tobacco use dependence, counseling, and cessation resources (i.e., links to text-based support, self-change booklet). Varenicline helps to reduce cravings for tobacco use and decreases the pleasurable effects of cigarettes and other tobacco products.

NCT ID: NCT05997901 Recruiting - Smoking Cessation Clinical Trials

Helping People Adhere to Their Varenicline Treatment by Co-creating a Conversational Agent: A Feasibility Study

Start date: October 12, 2022
Phase: N/A
Study type: Interventional

The goal of this feasibility study is to co-create and evaluate a theory informed, evidence-based, patient-centered healthbot aimed at helping people adhere to their varenicline regimen. The main research questions it aims to answer are: 1. What are the challenges to varenicline adherence and strategies to overcome such challenges from the perspective of service users and service providers? 2. What features of a healthbot would help improve adherence to varenicline? 3. Does a healthbot developed to improve varenicline adherence meet the implementation outcomes and increase medication adherence as well as smoking cessation? The study will be conducted using the Discover Design Build and Test framework. - In the Discover phase, a literature review, 20 service user interviews, and 20 healthcare provider interviews will help inform the challenges to varenicline adherence, strategies to overcome them using the Capability, Opportunity, Motivation, and Behavior framework, and the ways in which a healthbot might help improve adherence. - In the Design, Build and Test phase, 40 participants will interact with a preliminary healthbot using the Wizard of Oz method, then provide feedback about their experiences in a follow up interview; and team members, including clinicians and researchers, will beta test and validate a more refined healthbot. In the last phase, a non-randomized single arm feasibility study, 40 participants will interact with the healthbot for 12 weeks and provide feedback about the acceptability, appropriateness, fidelity, adoption, and usability of the healthbot; and researchers will assess participants' medication adherence and smoking status.

NCT ID: NCT05994703 Recruiting - Smoking Cessation Clinical Trials

Assisting Smokers to Switch to an e-Cigarette by Accelerating Learning of Adaptive Habits Using D-cycloserine

Start date: October 20, 2023
Phase: Phase 2
Study type: Interventional

This study will evaluate the effects of a reward devaluation strategy, which has been researched in the past, combined/augmented with the medication d-cycloserine in assisting smokers to switch from combustible cigarette (CC) to Juul.

NCT ID: NCT05961813 Recruiting - Smoking Cessation Clinical Trials

Intervention for Smoking Cessation in Pre-Surgical Patients.

Start date: May 20, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to assess efficacy of an intensive pre-surgical intervention to quit smoking in smoking patients who will be operated on implant orthopedic surgery or general and urological surgery. The main question[s] it aims to answer are: - Evaluate the efficacy of intensive pre surgical intervention to quit smoking compared to a brief intervention - Evaluate the implementation of this protocol. Participants will be randomized to 2 intervention groups (patients programmed for protesic implant orthopedic surgery in the first group, and general and urological surgery) and 2 control groups (stratified in the same manner as the intervention groups), and will be monitored through telematic check ups via phone calls.

NCT ID: NCT05897346 Recruiting - Smoking Cessation Clinical Trials

Training Secondary School Students as Anti-smoke Ambassadors Using the Service-learning Model

Start date: April 1, 2023
Phase: N/A
Study type: Interventional

Building the community's capacity by training youngsters to refer smokers to professional smoking cessation services offers a good strategy to support smoking cessation. Peer pressure is considered the most common reason for smoking in young people. Smoking cessation interventions that target peers are likely to have substantial effects. This health promotion project based on the service-learning model will provide opportunity for young people to learn and practice the AWARD model with hands-on experience under the supervision of nursing students who are considered experienced peer counselors.