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Sigmoid Neoplasms clinical trials

View clinical trials related to Sigmoid Neoplasms.

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NCT ID: NCT05943041 Recruiting - Cancer Clinical Trials

Live Biotherapeutic Product GB104 Phase 1 Study in Colorectal Cancer

Start date: April 28, 2023
Phase: Phase 1
Study type: Interventional

Prospective, open label, multi-dose, sequential dose escalation, single-center, Phase 1 trial

NCT ID: NCT05730595 Not yet recruiting - Clinical trials for Colorectal Neoplasms

Fluorescence Laparoscopic Navigation for Rectal Cancer and Sigmoid Colon Cancer

FLORA-01
Start date: September 1, 2023
Phase: N/A
Study type: Interventional

To explore the short-term and long-term outcomes of fluorescence laparoscopic navigation D2 lymph node dissection for colorectal cancer surgery by comparing it with D3 lymph node dissection.

NCT ID: NCT05068180 Recruiting - Prostatic Neoplasms Clinical Trials

Low-dose Neuroleptanalgesia for Postoperative Delirium in Elderly Patients

Start date: October 5, 2021
Phase: Phase 4
Study type: Interventional

Postoperative delirium(POD)is a common complication that can directly affect important clinical outcomes, and exert an enormous burden on patients, their families, hospitals, and public resources. In order to evaluate whether an intraoperative administration of low-dose neuroleptanalgesia reduces postoperative delirium, droperidol 1.25 mg and fentanyl 0.025 mg or normal saline is used by intravenous injection 30 minutes before the end of the operation, in elderly patients with non-cardiac major surgery under general anesthesia. The efficiency and safety of neuroleptanalgesia on the incidence of POD would be evaluated in elderly patients.

NCT ID: NCT04744792 Completed - Quality of Life Clinical Trials

QoL of Colorectal Cancer Patients and Spouses

Start date: March 1, 2006
Phase:
Study type: Observational

The aim of the present prospective, comparative study was to compare the quality of life (QoL) of patients after colorectal surgery to the QoL of their spouses. The study included patients who underwent curative surgery for colorectal carcinoma (n = 100; abdominoperineal excision [n = 33], low anterior resection [n = 33], left hemicolectomy [n = 34]) and their spouses (n = 100). The patients and spouses completed the Medical Outcome Study 36-item Short Form Survey (SF-36) and the World Health Organization Disability Assessment Schedule II (WHODAS-II) preoperatively and at postoperative months 15 to 18. The QoL of patients and that of their spouses changed following surgery for colorectal cancer. These changes were more significant among male patients' spouses.

NCT ID: NCT04729283 Recruiting - Sigmoid Cancer Clinical Trials

Comparison of Quality of Life and Functionnal Resultats After Sigmodectomy Between Diverticulitis and Cancer

SIG-QOL
Start date: April 12, 2021
Phase:
Study type: Observational

The aim of this present study is to compare functional results and quality of life after sigmoidectomy for diverticulitis and sigmoid cancer.

NCT ID: NCT03774134 Active, not recruiting - Sigmoid Neoplasms Clinical Trials

Five Year Oncological Outcome After CME for Sigmoid Colon Cancer

Start date: June 1, 2008
Phase:
Study type: Observational

Study based in existing databases investigating the causal oncological treatment effects of complete mesocolic excision on UICC stage I-III sigmoid colon cancer

NCT ID: NCT03628248 Completed - Cancer, Rectum Clinical Trials

Effect of Endovascular Inferior Mesenteric Artery Embolization on Colonic Perfusion Prior to Rectal Surgery for Rectal Tumor or Sigmoid Colon Surgery

AMIREMBOL
Start date: March 10, 2020
Phase: N/A
Study type: Interventional

The investigators hypothesize that a primary embolization, 3-4 weeks before surgery, would allow development of vascular collaterality, in particular for the marginal artery which will ensure a better colonic perfusion.

NCT ID: NCT03531606 Completed - Clinical trials for Sigmoid Colon Cancer

The Effects of Mechnikov Probiotics on Symptom and Surgical Outcome

Start date: December 12, 2016
Phase: N/A
Study type: Interventional

The purpose of this clinical trial study was to evaluate the prevalence of colon cancer among the symptom (s) of anterior resection syndrome that may occur after surgery in patients for efficacy and safety in Metchnik probiotic ingestion.

NCT ID: NCT03390517 Completed - Rectal Cancer Clinical Trials

A Study of Perfusion of Colorectal Anastomosis Using FLuorescence AnGiography (FLAG-trial)

FLAG
Start date: November 9, 2017
Phase: N/A
Study type: Interventional

This is a randomized, controlled, parallel study to determine the difference in post-operative anastomotic leak rate of colorectal anastomosis where colon and rectal tissue perfusion is evaluated using fluorescence angiography with indocyanine green and without this method.

NCT ID: NCT03259828 Completed - Sigmoid Cancer Clinical Trials

Sigmoid Colon Organ Motion in Radiotherapy

Start date: December 6, 2017
Phase: N/A
Study type: Interventional

Radiotherapy is used in cancer treatment to eradicate microscopic cancer cells to lower the risk of recurrence. The radiotherapy plan must account for organ movement inside the body to ascertain adequate dose is delivered to the target. Knowledge of the magnitude is crucial to radiotherapy treatment planning. This study aims to quantify the movement of the sigmoid colon between different fractions of radiotherapy treatment (interfraction motion) and within the same fraction (intrafraction motion). This knowledge will help us determine the optimal margin to use in radiotherapy treatment planning.