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Side Effects clinical trials

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NCT ID: NCT02143141 Terminated - Clinical trials for Postoperative Pain Management

Low Pain Prediction in Cesarean Section Patients

Start date: November 2011
Phase: Phase 4
Study type: Interventional

The investigators are attempting to see if eliminating the amount of long acting spinal narcotic during cesarean section delivery will demonstrate pain scores with movement when evaluated 24 hours postoperatively as those that receive the standard dosage of spinal narcotic when combined with oral acetaminophen or placebo. The investigators also are evaluating if there are decreased side effects related to decreased narcotic usage.

NCT ID: NCT02003560 Active, not recruiting - Breast Cancer Clinical Trials

Accelerated Partial Breast Irradiation With 3D-CRT and IMRT

APERT
Start date: December 2006
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine in a phase II clinical trial whether accelerated partial breast irradiation after breast conserving surgery using 3 dimensional external beam radiotherapy (3D-CRT) and intensity modulated radiotherapy (IMRT) for low-risk invasive breast cancer patients is safe without causing serious late radiation side-effects.

NCT ID: NCT01908491 Completed - Pain Clinical Trials

Comparison of IV PCA and Wound Infusion After Repair of Pectus Excavatum

Start date: October 2012
Phase: Phase 4
Study type: Interventional

Postoperative pain management is a major problem after repair of pectus excavatum.Various methods of pain management have been introduced. However, the effects of continuous wound infusion of local anesthetics through ON-Q catheters were not well evaluated in pectus surgery. Therefore, we conducted prospective randomized controlled study to compare the effects of IV PCA and continuous wound infusion after repair of pectus excavatum.

NCT ID: NCT00456820 Completed - Depression Clinical Trials

Wellbutrin XL Effects on SSRIs Induced Changes

Start date: July 2004
Phase: Phase 4
Study type: Interventional

The purpose of this study is to find out differences in activation of mood regulating areas of the brain in response to negative and positive pictures, before and after 6 weeks of additional Wellbutrin XL treatment. Participants should have been treated for depression with an SSRI medication (e.g., Prozac, Zoloft, Paxil, Celexa or Lexapro) and have decreased depression symptoms but also be experiencing side effects of medications such as sexual side effects and feelings of apathy (indifference, lack of interest) and lack of full emotional response. We will first take a brain scan to measure activity in different parts of the brain, while subjects are seeing pictures, using Magnetic Resonance Imaging (MRI) scan. Then we will add Wellbutrin XL - another well-known antidepressant that acts by increasing the chemical dopamine in the brain, to subjects' treatment. Wellbutrin addition is useful in decreasing the sexual side effects of SSRIs. After treatment with Wellbutrin XL for 6 weeks subjects will have a second MRI scan with picture rating.