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Shortness of Breath clinical trials

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NCT ID: NCT05403619 Completed - Clinical trials for Acute Respiratory Failure

Enhanced FoCUS in Patients With Shortness of Breath

eFOCUS
Start date: January 1, 2018
Phase:
Study type: Observational

Retrospective observational study performed in a internal medicine ward of a French university hospital. Included patients were hospitalized for acute shortness of breath who have benefited from a eFOCUS which was defined as a focused cardiac Ultrasound with utilization of Doppler measurements. The objectives were the therapeutic and diagnosis changes induced by eFoCUS. The primary endpoint was defined by the pooled introduction or discontinuation of diuretics, antibiotics or anticoagulants associated with eFoCUS results.

NCT ID: NCT05326802 Completed - Clinical trials for Cardiovascular Diseases

The U.S. Embryologist Fatigue Study

FUSE
Start date: April 7, 2022
Phase:
Study type: Observational

The purpose of the study is to determine physical and mental health issues of U.S. embryologists related to their occupational characteristics, and how workplace fatigue and burnout may affect their quality of life, cynicism, interactions with patients, attention to detail, and lead to human error, the cause of the most severe IVF incidents that often make headlines and result in costly litigation. It will also correlate how the current manual workflows contribute to these health issues, and what measures can be taken to improve both working conditions and embryologists' health, and, therefore, improve patient care.

NCT ID: NCT05304494 Withdrawn - Asthma Clinical Trials

Sentinel - Triaging Acute Breathlessness Using Multi-Modal Biomarkers

Start date: March 2022
Phase:
Study type: Observational

The Sentinel-001 study aims to identify a combination of biomarkers suitable for triage of breathlessness.

NCT ID: NCT05139979 Completed - COVID-19 Clinical Trials

Yogic Breathing and Guided Meditation for Long Covid Symptoms

Start date: September 15, 2021
Phase: N/A
Study type: Interventional

This study aims to assess the impact of brief digitally delivered breathing practice and guided meditation on post-Covid physical and mental symptoms in Long Covid Patients.

NCT ID: NCT04958863 Completed - Shortness of Breath Clinical Trials

Impact of Facemasks on Running During COVID-19 Pandemic

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

Randomized crossover clinical trial in which a group of runners are ask to complete a 15 minutes standardized physical test on a treadmill. The same group of participants are randomized to the order in which they use a facemask (surgical mask, polyester reusable cloth mask) or no mask, while running. Each test, according to the type of mask or no mask, are held on different dates. Heart rate, oxygen saturation and shortness of breath are measured every 3 minutes during the test.

NCT ID: NCT04827563 Recruiting - Multiple Myeloma Clinical Trials

Dyspnea and Cardiotoxicity in Multiple Myeloma Patients Who Receive Carfilzomib

Start date: March 22, 2021
Phase:
Study type: Observational

This study will explore why some multiple myeloma patients who receive carfilzomib (an anti-cancer medication) experience shortness of breath while others do not. The purpose of this research is to gather information on the effectiveness of the EndoPAT device, which is FDA-approved to assess the health of a patient's blood vessels. These assessments will help doctors leading the study determine the reasons why patients may develop shortness of breath (dyspnea) when being treated with carfilzomib and ways to better prevent this shortness of breath.

NCT ID: NCT04715932 Completed - Pain Clinical Trials

Study of Hesperidin Therapy on COVID-19 Symptoms (HESPERIDIN)

Hesperidin
Start date: February 18, 2021
Phase: Phase 2
Study type: Interventional

The main aim of this study is to determine the effects of short-term treatment with hesperidin on COVID-19 symptoms in comparison with a placebo. Treatment effects will be observed through a symptoms diary that will be completed by participants throughout the study and by taking the oral temperature daily.

NCT ID: NCT04373499 Completed - Asthma Clinical Trials

Virtual Teach-to-Goal Education vs. Brief Education for Children

V-TTG vs BI
Start date: January 16, 2019
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the effectiveness of two different ways to teach hospitalized children how to use a metered dose inhaler and to follow-up after discharge home from the hospital to determine durability of the education.

NCT ID: NCT04332198 Not yet recruiting - Clinical trials for Amyotrophic Lateral Sclerosis

Neurobiological and Immunological Mechanisms of Dyspnea in ALS (BIOPNEA)

Start date: July 2023
Phase: N/A
Study type: Interventional

Dyspnea; subjective experience of respiratory discomfort; which produces negative emotional experience, is the most common symptom of patients afflicted with chronic respiratory failure and its treatments are limited. Amyotrophic Lateral Sclerosis (ALS) related - dyspnea, due to diaphragmatic dysfunction, is similar to dyspnea during mechanical inspiratory load (activation of the supplementary motor area, SMA). The perception of pain and dyspnea is processed in similar brain areas (insula, dorsal anterior cingulate cortex, amygdala and medial thalamus) and in ALS; relieving dyspnea by noninvasive ventilation (NIV) is associated with decreased pain thresholds. Otherwise, it is reported systemic elevations of pro-inflammatory cytokines in chronic pain patients, correlating with intensity of pain, and during respiratory load in healthy volunteers. The objectives are to evaluate the cytokines and endorphins rates variations after initiation of NIV in ALS patients, and to correlate cytokines and endorphins rates with the intensity of the affective component and the intensity of the sensory component of dyspnea. The investigators will perform a prospective, experimental study, including 30 ALS patients. Dyspnea, ventilatory and cardiac settings, electromyographic recording of the scalene muscle and biological assays (ACTH, endorphin, Neuropeptide P, BDNF, IL1, IL6, IL8, IL10, TNF), will be measured during spontaneous breathing and during NIV at different times after initiation. The investigators expect a reduction of immunological and neurobiological markers after relieving dyspnea by NIV. This work could lead to the development of new treatments for dyspnea.

NCT ID: NCT03951779 Completed - Shortness of Breath Clinical Trials

Diagnostic Utility of Exercise Cardiac Magnetic Resonance in the Assessment of Cardiac Dyspnea.

Start date: December 14, 2018
Phase: N/A
Study type: Interventional

Researchers are examining the diagnostic utility of an exercise cardiac MRI (eCMR) in the assessment of cardiac dyspnea (shortness of breath).